Protein: CPSM
Carbamoyl-phosphate synthase [ammonia], mitochondrial (EC 6.3.4.16) (Carbamoyl-phosphate synthetase I) (CPSase I)

Gene: CPSM, CPS1
Organism: Homo sapiens
Interactions: 121
UniProt ID: P31327

Gene Ontology (top 5):
GO:0000050 - urea cycle
GO:0004087 - carbamoyl-phosphate synthase (ammonia) activity
GO:0004088 - carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GO:0004175 - endopeptidase activity
GO:0005509 - calcium ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

679462

KIRR2
Kin of IRRE-like protein 2

3

0

High-throughput

0.638

High

258664

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

2

2

High-throughput

0.628

High

326301

BPNT1
3'(2'),5'-bisphosphate nucleotidase 1

2

1

High-throughput

0.628

High

638233

RBTN2
Rhombotin-2

2

3

High-throughput

0.628

High

679438

YBEY
Endoribonuclease YbeY

2

3

High-throughput

0.628

High

679456

ACSM5
Acyl-coenzyme A synthetase ACSM5, mitochondrial

2

3

High-throughput

0.628

High

679477

FXRD1
FAD-dependent oxidoreductase domain-containing protein 1

2

1

High-throughput

0.628

High

679491

TMM70
Transmembrane protein 70, mitochondrial

2

1

High-throughput

0.628

High

679454

SYRM
Probable arginine--tRNA ligase, mitochondrial

2

3

High-throughput

0.611

High

679516

AGO2
Protein argonaute-2

2

2

High-throughput

0.611

High

679478

ARHGQ
Rho guanine nucleotide exchange factor 26

3

3

High-throughput

0.609

High

679440

1433Z
14-3-3 protein zeta/delta

2

6

High-throughput

0.571

High

679483

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.554

High

207017

XRCC3
DNA repair protein XRCC3

1

4

High-throughput

0.536

High

270914

KBL
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial

1

3

High-throughput

0.536

High

272333

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

1

High-throughput

0.536

High

336845

OTC
Ornithine transcarbamylase, mitochondrial

1

4

High-throughput

0.536

High

501737

BIP
Endoplasmic reticulum chaperone BiP

1

6

High-throughput

0.536

High

613926

TBG1
Tubulin gamma-1 chain

1

7

High-throughput

0.536

High

638481

RBTN1
Rhombotin-1

1

2

High-throughput

0.536

High

646372

KAD4
Adenylate kinase 4, mitochondrial

1

2

High-throughput

0.536

High

679431

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

2

High-throughput

0.536

High

679434

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

2

High-throughput

0.536

High

679443

FOXF1
Forkhead box protein F1

1

1

High-throughput

0.536

High

679445

DHRS2
Dehydrogenase/reductase SDR family member 2, mitochondrial

1

2

High-throughput

0.536

High

679452

RM23
Large ribosomal subunit protein uL23m

1

1

High-throughput

0.536

High

679458

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

1

High-throughput

0.536

High

679460

FAHD1
Oxaloacetate decarboxylase, mitochondrial

1

2

High-throughput

0.536

High

679475

TRI43
Tripartite motif-containing protein 43

1

3

High-throughput

0.536

High

679479

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

1

3

High-throughput

0.536

High

679480

RT24
Small ribosomal subunit protein uS3m

1

2

High-throughput

0.536

High

679482

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.536

High

679484

DNJC7
DnaJ homolog subfamily C member 7

1

5

High-throughput

0.536

High

679486

TBA1C
Tubulin alpha-1C chain

1

3

High-throughput

0.536

High

679487

LSMD1
N-alpha-acetyltransferase 38, NatC auxiliary subunit

1

2

High-throughput

0.536

High

679490

MYL10
Myosin regulatory light chain 10

1

1

High-throughput

0.536

High

679492

SCOT2
Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial

1

1

High-throughput

0.536

High

679493

LDH6B
L-lactate dehydrogenase A-like 6B

1

3

High-throughput

0.536

High

679496

MTG2
Mitochondrial ribosome-associated GTPase 2

1

6

High-throughput

0.536

High

679509

DIC
Mitochondrial dicarboxylate carrier

1

1

High-throughput

0.536

High

679513

MRM2
rRNA methyltransferase 2, mitochondrial

1

2

High-throughput

0.536

High

679519

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

3

High-throughput

0.536

High

679521

RT02
Small ribosomal subunit protein uS2m

1

4

High-throughput

0.536

High

245314

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.513

High

679441

RT25
Small ribosomal subunit protein mS25

1

0

High-throughput

0.513

High

679464

RM21
Large ribosomal subunit protein bL21m

1

0

High-throughput

0.513

High

679500

DMAP1
DNA methyltransferase 1-associated protein 1

1

0

High-throughput

0.513

High

679518

CLC11
C-type lectin domain family 11 member A

1

0

High-throughput

0.513

High

488586

ARAF
Serine/threonine-protein kinase A-Raf

1

5

Small-scale

0.508

High

203881

HTRA2
Serine protease HTRA2, mitochondrial

1

2

High-throughput

0.489

High

555313

H2AX
Histone H2AX

1

2

High-throughput

0.489

High

679437

AP1S2
AP-1 complex subunit sigma-2

1

1

High-throughput

0.489

High

679467

FA83F
Protein FAM83F

1

1

High-throughput

0.489

High

679468

F174A
Membrane protein FAM174A

1

1

High-throughput

0.489

High

679489

NPS3B
Protein NipSnap homolog 3B

1

4

High-throughput

0.489

High

679499

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

2

High-throughput

0.489

High

679506

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.489

High

679510

NPS3A
Protein NipSnap homolog 3A

1

4

High-throughput

0.489

High

679485

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

4

Small-scale

0.481

High

148438

CTRO
Citron Rho-interacting kinase

1

7

High-throughput

0.479

High

181804

SOCS1
Suppressor of cytokine signaling 1

1

6

Small-scale

0.479

High

308436

KI20A
Kinesin-like protein KIF20A

1

3

High-throughput

0.479

High

380567

K2C1
Keratin, type II cytoskeletal 1

1

1

Small-scale

0.479

High

393063

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

1

High-throughput

0.479

High

475387

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

11

Small-scale

0.479

High

610253

CBL
E3 ubiquitin-protein ligase CBL

1

6

High-throughput

0.479

High

646661

1433T
14-3-3 protein theta

1

6

High-throughput

0.479

High

679430

PHB1
Prohibitin 1

1

3

High-throughput

0.479

High

679432

GATA4
Transcription factor GATA-4

1

2

High-throughput

0.479

High

679433

MAP1B
Microtubule-associated protein 1B

1

1

High-throughput

0.479

High

679435

TSP3
Thrombospondin-3

1

2

High-throughput

0.479

High

679439

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

679442

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.479

High

679444

TIF1B
Transcription intermediary factor 1-beta

1

13

High-throughput

0.479

High

679447

EMC2
ER membrane protein complex subunit 2

1

1

High-throughput

0.479

High

679450

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

679463

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

679465

RHG24
Rho GTPase-activating protein 24

1

2

High-throughput

0.479

High

679470

NUDC2
NudC domain-containing protein 2

1

2

High-throughput

0.479

High

679471

MAIP1
m-AAA protease-interacting protein 1, mitochondrial

1

1

High-throughput

0.479

High

679472

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

Small-scale

0.479

High

679473

HDAC2
Histone deacetylase 2

1

14

High-throughput

0.479

High

679476

CHM4C
Charged multivesicular body protein 4c

1

3

High-throughput

0.479

High

679481

AURKB
Aurora kinase B

1

4

High-throughput

0.479

High

679488

RIOK1
Serine/threonine-protein kinase RIO1

1

4

High-throughput

0.479

High

679494

SPRTN
DNA-dependent metalloprotease SPRTN

1

3

High-throughput

0.479

High

679495

CHM4B
Charged multivesicular body protein 4b

1

3

High-throughput

0.479

High

679497

PKHA4
Pleckstrin homology domain-containing family A member 4

1

9

High-throughput

0.479

High

679498

ECT2
Protein ECT2

1

3

High-throughput

0.479

High

679502

ANM8
Protein arginine N-methyltransferase 8

1

2

Small-scale

0.479

High

679503

FBX6
F-box only protein 6

1

2

High-throughput

0.479

High

679504

SALL1
Sal-like protein 1

1

1

High-throughput

0.479

High

679505

PIHD1
PIH1 domain-containing protein 1

1

2

High-throughput

0.479

High

679508

HDAC6
Histone deacetylase 6

1

13

High-throughput

0.479

High

679511

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

679512

TES
Testin

1

2

High-throughput

0.479

High

209704

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

363725

ALBU
Albumin

1

0

Small-scale

0.458

High

679466

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

679469

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

373767

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

5

Small-scale

0.457

High

679446

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

1

Small-scale

0.445

High

679451

PTN14
Tyrosine-protein phosphatase non-receptor type 14

1

1

High-throughput

0.445

High

679507

UXT
Protein UXT

1

1

Small-scale

0.445

High

224322

RAD21
Double-strand-break repair protein rad21 homolog

1

1

High-throughput

0.437

High

679448

TNIP1
TNFAIP3-interacting protein 1

1

7

High-throughput

0.437

High

679449

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

3

High-throughput

0.437

High

679455

VIR
Protein virilizer homolog

1

2

High-throughput

0.437

High

679461

RICTR
Rapamycin-insensitive companion of mTOR

1

2

Small-scale

0.437

High

679501

ANLN
Anillin

1

3

High-throughput

0.437

High

679517

TRI33
E3 ubiquitin-protein ligase TRIM33

1

13

High-throughput

0.437

High

679520

AAR2
Protein AAR2 homolog

1

2

High-throughput

0.437

High

679474

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.426

High

679453

DB121
Beta-defensin 121

2

0

High-throughput

0.328

High

679514

DKKL1
Dickkopf-like protein 1

2

0

High-throughput

0.328

High

551078

ITF2
Transcription factor 4

1

0

High-throughput

0.279

Low

679436

FOXG1
Forkhead box protein G1

1

0

High-throughput

0.279

Low

679457

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.279

Low

679459

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.249

Low

679515

FBXL4
F-box/LRR-repeat protein 4

1

0

Small-scale

0.249

Low

679522

ASB1
Ankyrin repeat and SOCS box protein 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024