Protein: SMG8
Nonsense-mediated mRNA decay factor SMG8 (Amplified in breast cancer gene 2 protein) (Protein smg-8 homolog)

Gene: SMG8
Organism: Homo sapiens
Interactions: 102
UniProt ID: Q8ND04

Gene Ontology (top 5):
GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0005829 - cytosol
GO:0045859 - regulation of protein kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1241995

SMG1
Serine/threonine-protein kinase SMG1

2

0

Small-scale

0.801

High

1242008

SMG9
Nonsense-mediated mRNA decay factor SMG9

3

1

Small-scale

0.675

High

666940

TKT
Transketolase

2

0

High-throughput

0.602

High

1022944

CDC16
Cell division cycle protein 16 homolog

2

0

High-throughput

0.602

High

1219936

BBS7
Bardet-Biedl syndrome 7 protein

2

0

High-throughput

0.602

High

1241991

AZIN2
Antizyme inhibitor 2

2

0

High-throughput

0.602

High

1241997

DNJC7
DnaJ homolog subfamily C member 7

2

0

High-throughput

0.602

High

1242010

DOCK5
Dedicator of cytokinesis protein 5

2

0

High-throughput

0.602

High

1242012

SYIM
Isoleucine--tRNA ligase, mitochondrial

2

0

High-throughput

0.602

High

1242022

CRYL1
Lambda-crystallin homolog

2

0

High-throughput

0.602

High

1242026

RBM8A
RNA-binding protein 8A

2

0

Small-scale

0.585

High

1216983

LRC49
Leucine-rich repeat-containing protein 49

2

1

High-throughput

0.574

High

1219194

Z3H7A
Zinc finger CCCH domain-containing protein 7A

2

2

High-throughput

0.533

High

1123529

HS904
Putative heat shock protein HSP 90-alpha A4

2

0

High-throughput

0.528

High

149891

RFXK
DNA-binding protein RFXANK

1

0

High-throughput

0.513

High

180065

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

0

High-throughput

0.513

High

277333

ST1C4
Sulfotransferase 1C4

1

0

High-throughput

0.513

High

311731

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

0

High-throughput

0.513

High

323900

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

428312

TBB5
Tubulin beta chain

1

0

High-throughput

0.513

High

515905

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.513

High

568996

CAN2
Calpain-2 catalytic subunit

1

0

High-throughput

0.513

High

996114

HDHD1
Pseudouridine-5'-phosphatase

1

0

High-throughput

0.513

High

1069430

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.513

High

1138355

CBPC6
Cytosolic carboxypeptidase 6

1

0

High-throughput

0.513

High

1240489

SPC24
Kinetochore protein Spc24

1

0

High-throughput

0.513

High

1241987

NT5C
5'(3')-deoxyribonucleotidase, cytosolic type

1

0

High-throughput

0.513

High

1241990

RENT1
Regulator of nonsense transcripts 1

1

0

Small-scale

0.513

High

1241992

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.513

High

1242001

DUS16
Dual specificity protein phosphatase 16

1

0

High-throughput

0.513

High

1242002

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

1242004

COMD5
COMM domain-containing protein 5

1

0

High-throughput

0.513

High

1242015

SPHK1
Sphingosine kinase 1

1

0

High-throughput

0.513

High

1242017

KLH14
Kelch-like protein 14

1

0

High-throughput

0.513

High

1242007

DRC3
Dynein regulatory complex subunit 3

1

1

High-throughput

0.489

High

1192329

YTHD3
YTH domain-containing family protein 3

1

1

High-throughput

0.479

High

1242024

YTHD2
YTH domain-containing family protein 2

1

1

High-throughput

0.479

High

200891

CTIF
CBP80/20-dependent translation initiation factor

1

0

High-throughput

0.458

High

989012

FMR1
Fragile X messenger ribonucleoprotein 1

1

0

High-throughput

0.458

High

1034931

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

0

High-throughput

0.458

High

1035511

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

1036740

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1168787

MEX3B
RNA-binding protein MEX3B

1

0

High-throughput

0.458

High

1241986

LS14A
Protein LSM14 homolog A

1

0

High-throughput

0.458

High

1242011

ANLN
Anillin

1

0

High-throughput

0.458

High

1242019

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1242020

APC4
Anaphase-promoting complex subunit 4

1

0

Small-scale

0.458

High

1242021

RUVB1
RuvB-like 1

1

0

Small-scale

0.458

High

832859

TSP3
Thrombospondin-3

3

0

High-throughput

0.347

High

341282

FA9
Coagulation factor IX

2

0

High-throughput

0.328

High

600621

EPHA1
Ephrin type-A receptor 1

2

0

High-throughput

0.328

High

1152359

CNDH2
Condensin-2 complex subunit H2

2

0

High-throughput

0.328

High

1165329

LYPD4
Ly6/PLAUR domain-containing protein 4

2

0

High-throughput

0.328

High

1172559

TPGS1
Tubulin polyglutamylase complex subunit 1

2

0

High-throughput

0.328

High

1239461

GALD1
Glutamine amidotransferase-like class 1 domain-containing protein 1

2

0

High-throughput

0.328

High

1242000

NICN1
Nicolin-1

2

0

High-throughput

0.328

High

946048

DLK1
Protein delta homolog 1

2

0

High-throughput

0.318

High

1241999

CAB45
45 kDa calcium-binding protein

2

0

High-throughput

0.318

High

171155

CETN3
Centrin-3

1

0

High-throughput

0.279

Low

179229

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.279

Low

245717

B4GT2
Beta-1,4-galactosyltransferase 2

1

0

High-throughput

0.279

Low

296463

ACL6B
Actin-like protein 6B

1

0

High-throughput

0.279

Low

441626

TRFM
Melanotransferrin

1

0

High-throughput

0.279

Low

645992

CRBB3
Beta-crystallin B3

1

0

High-throughput

0.279

Low

796139

MAGA9
Melanoma-associated antigen 9

1

0

High-throughput

0.279

Low

942533

CTG1B
Cancer/testis antigen 1

1

0

High-throughput

0.279

Low

975452

PPARD
Peroxisome proliferator-activated receptor delta

1

0

High-throughput

0.279

Low

1012142

LR74A
Leucine-rich repeat-containing protein 74A

1

0

High-throughput

0.279

Low

1030839

SG2A2
Mammaglobin-A

1

0

High-throughput

0.279

Low

1073070

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.279

Low

1100091

INF2
Inverted formin-2

1

0

High-throughput

0.279

Low

1197895

GLT10
Polypeptide N-acetylgalactosaminyltransferase 10

1

0

High-throughput

0.279

Low

1232934

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1241988

NPRL2
GATOR1 complex protein NPRL2

1

0

High-throughput

0.279

Low

1241989

CA054
Uncharacterized protein C1orf54

1

0

High-throughput

0.279

Low

1241993

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.279

Low

1241994

F167A
Protein FAM167A

1

0

High-throughput

0.279

Low

1241996

CIB3
Calcium and integrin-binding family member 3

1

0

High-throughput

0.279

Low

1241998

NPAS1
Neuronal PAS domain-containing protein 1

1

0

High-throughput

0.279

Low

1242005

DNAI2
Dynein axonemal intermediate chain 2

1

0

High-throughput

0.279

Low

1242018

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

1242025

PCDB3
Protocadherin beta-3

1

0

High-throughput

0.279

Low

1242027

NPTN
Neuroplastin

1

0

High-throughput

0.279

Low

347354

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

385182

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

596010

EFNA1
Ephrin-A1

1

0

High-throughput

0.249

Low

651713

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

719000

PHB1
Prohibitin 1

1

0

High-throughput

0.249

Low

968877

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.249

Low

1121530

EIPR1
EARP and GARP complex-interacting protein 1

1

0

High-throughput

0.249

Low

1170866

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1201244

FHI2B
FHF complex subunit HOOK-interacting protein 2B

1

0

High-throughput

0.249

Low

1236378

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

High-throughput

0.249

Low

1241985

RN214
RING finger protein 214

1

0

High-throughput

0.249

Low

1242003

UNK
RING finger protein unkempt homolog

1

0

High-throughput

0.249

Low

1242006

MKRN2
E3 ubiquitin-protein ligase makorin-2

1

0

High-throughput

0.249

Low

1242009

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1242013

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

0

High-throughput

0.249

Low

1242023

T22D4
TSC22 domain family protein 4

1

0

High-throughput

0.249

Low

1169875

PKHG7
Pleckstrin homology domain-containing family G member 7

1

0

High-throughput

0.232

Low

1242014

TRM1
tRNA

1

0

High-throughput

0.232

Low

1242016

PP4RL
Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024