Protein: MBP
Myelin basic protein (MBP) (Myelin A1 protein) (Myelin membrane encephalitogenic protein)

Gene: MBP
Organism: Homo sapiens
Interactions: 80
UniProt ID: P02686

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0002020 - protease binding
GO:0005516 - calmodulin binding
GO:0005634 - nucleus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

362061

MK01
Mitogen-activated protein kinase 1

16

7

Small-scale

0.763

High

362104

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

6

2

High-throughput

0.738

High

362092

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

6

1

Small-scale

0.729

High

362059

MK03
Mitogen-activated protein kinase 3

5

6

Small-scale

0.712

High

171188

CTDSL
CTD small phosphatase-like protein

4

2

High-throughput

0.698

High

362091

MK14
Mitogen-activated protein kinase 14

4

10

Small-scale

0.688

High

362069

CDK9
Cyclin-dependent kinase 9

2

8

Small-scale

0.602

High

362079

KPCZ
Protein kinase C zeta type

2

6

Small-scale

0.602

High

362054

IDE
Insulin-degrading enzyme

2

0

High-throughput

0.602

High

362048

A4
Amyloid-beta precursor protein

2

0

Small-scale

0.594

High

362103

NEUL
Neurolysin, mitochondrial

2

0

High-throughput

0.585

High

262215

ULK1
Serine/threonine-protein kinase ULK1

2

0

Small-scale

0.577

High

354654

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

1

Small-scale

0.575

High

362060

DMA
HLA class II histocompatibility antigen, DM alpha chain

1

1

Small-scale

0.575

High

362058

PTAFR
Platelet-activating factor receptor

1

2

High-throughput

0.568

High

362064

CCR1
C-C chemokine receptor type 1

1

1

High-throughput

0.568

High

362075

MYPR
Myelin proteolipid protein

2

0

Small-scale

0.560

High

362055

NCK1
SH2/SH3 adapter protein NCK1

2

0

High-throughput

0.547

High

362051

ADRB2
Beta-2 adrenergic receptor

1

0

High-throughput

0.543

High

362097

TSC1
Hamartin

1

2

High-throughput

0.541

High

362052

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.513

High

362063

NMT1
Glycylpeptide N-tetradecanoyltransferase 1

1

0

High-throughput

0.513

High

362085

SQSTM
Sequestosome-1

1

0

Small-scale

0.505

High

173805

MK13
Mitogen-activated protein kinase 13

1

10

Small-scale

0.501

High

270359

KS6A5
Ribosomal protein S6 kinase alpha-5

1

2

Small-scale

0.501

High

362046

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

Small-scale

0.501

High

362049

KPCB
Protein kinase C beta type

1

6

Small-scale

0.501

High

362050

CDK1
Cyclin-dependent kinase 1

1

1

Small-scale

0.501

High

362056

KPCA
Protein kinase C alpha type

1

6

Small-scale

0.501

High

362065

KPCI
Protein kinase C iota type

1

7

Small-scale

0.501

High

362066

MK08
Mitogen-activated protein kinase 8

1

9

Small-scale

0.501

High

362067

CDK8
Cyclin-dependent kinase 8

1

8

Small-scale

0.501

High

362068

CDK7
Cyclin-dependent kinase 7

1

2

Small-scale

0.501

High

362070

LIMK1
LIM domain kinase 1

1

2

Small-scale

0.501

High

362071

LIMK2
LIM domain kinase 2

1

1

Small-scale

0.501

High

362072

MK12
Mitogen-activated protein kinase 12

1

9

Small-scale

0.501

High

362077

CDK5
Cyclin-dependent kinase 5

1

2

Small-scale

0.501

High

362078

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

2

Small-scale

0.501

High

362080

KPCD
Protein kinase C delta type

1

6

Small-scale

0.501

High

362081

STK3
Serine/threonine-protein kinase 3

1

2

Small-scale

0.501

High

362082

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

5

Small-scale

0.501

High

362084

ILK
Integrin-linked protein kinase

1

1

Small-scale

0.501

High

362086

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

2

Small-scale

0.501

High

362089

MK11
Mitogen-activated protein kinase 11

1

10

Small-scale

0.501

High

362090

PKN1
Serine/threonine-protein kinase N1

1

3

Small-scale

0.501

High

362100

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

7

Small-scale

0.501

High

362101

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

3

Small-scale

0.501

High

362105

HIPK2
Homeodomain-interacting protein kinase 2

1

1

Small-scale

0.501

High

362110

STK39
STE20/SPS1-related proline-alanine-rich protein kinase

1

1

Small-scale

0.501

High

362112

TBK1
Serine/threonine-protein kinase TBK1

1

2

Small-scale

0.501

High

362113

TLK1
Serine/threonine-protein kinase tousled-like 1

1

1

Small-scale

0.501

High

362107

DUS22
Dual specificity protein phosphatase 22

1

0

High-throughput

0.493

High

149960

CTDS2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

1

2

High-throughput

0.489

High

362073

ATX1
Ataxin-1

1

0

High-throughput

0.486

High

362074

ATN1
Atrophin-1

1

0

High-throughput

0.486

High

362093

APTX
Aprataxin

1

0

High-throughput

0.486

High

153530

ANM5
Protein arginine N-methyltransferase 5

1

0

Small-scale

0.480

High

160315

AURKA
Aurora kinase A

1

0

Small-scale

0.480

High

337297

ABL1
Tyrosine-protein kinase ABL1

1

0

Small-scale

0.480

High

362057

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

0

Small-scale

0.480

High

362076

PRKDC
DNA-dependent protein kinase catalytic subunit

1

0

Small-scale

0.480

High

362083

2A5G
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform

1

0

Small-scale

0.480

High

362087

MELK
Maternal embryonic leucine zipper kinase

1

0

Small-scale

0.480

High

362098

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

1

0

Small-scale

0.480

High

362099

TRPM7
Transient receptor potential cation channel subfamily M member 7

1

0

Small-scale

0.480

High

362102

TSSK6
Testis-specific serine/threonine-protein kinase 6

1

0

Small-scale

0.480

High

362109

IRAK4
Interleukin-1 receptor-associated kinase 4

1

0

Small-scale

0.480

High

362053

MYH6
Myosin-6

1

1

High-throughput

0.479

High

321862

RIGI
Antiviral innate immune response receptor RIG-I

1

0

Small-scale

0.458

High

349050

RASH
GTPase HRas

1

0

High-throughput

0.458

High

362062

RXRB
Retinoic acid receptor RXR-beta

1

0

High-throughput

0.458

High

362096

KCNH5
Potassium voltage-gated channel subfamily H member 5

1

0

Small-scale

0.458

High

362111

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

362047

PRIO
Major prion protein

1

1

Small-scale

0.445

High

362106

PKHF2
Pleckstrin homology domain-containing family F member 2

2

0

High-throughput

0.316

High

362088

PGFRL
Platelet-derived growth factor receptor-like protein

1

0

High-throughput

0.282

High

352793

IFN21
Interferon alpha-21

1

0

High-throughput

0.279

Low

362094

ZER1
Protein zer-1 homolog

1

0

High-throughput

0.279

Low

362095

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.249

Low

362108

FBX34
F-box only protein 34

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024