Protein: PELI2
E3 ubiquitin-protein ligase pellino homolog 2 (Pellino-2) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase pellino homolog 2)

Gene: PELI2
Organism: Homo sapiens
Interactions: 48
UniProt ID: Q9HAT8

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0001934 - positive regulation of protein phosphorylation
GO:0005829 - cytosol
GO:0008592 - regulation of Toll signaling pathway
GO:0034450 - ubiquitin-ubiquitin ligase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

848485

IRAK1
Interleukin-1 receptor-associated kinase 1

7

10

Small-scale

0.752

High

151198

DVL2
Segment polarity protein dishevelled homolog DVL-2

3

1

Small-scale

0.661

High

1334833

IRAK4
Interleukin-1 receptor-associated kinase 4

2

2

Small-scale

0.660

High

1334836

TRAF6
TNF receptor-associated factor 6

3

3

Small-scale

0.650

High

201442

M3K7
Mitogen-activated protein kinase kinase kinase 7

3

4

Small-scale

0.640

High

981728

REL
Proto-oncogene c-Rel

2

1

High-throughput

0.606

High

780129

CCNF
Cyclin-F

2

0

Small-scale

0.593

High

1163038

TRAF7
E3 ubiquitin-protein ligase TRAF7

2

0

Small-scale

0.593

High

1254379

NEK9
Serine/threonine-protein kinase Nek9

2

0

Small-scale

0.593

High

740258

NUP62
Nuclear pore glycoprotein p62

2

0

High-throughput

0.580

High

970902

SP4
Transcription factor Sp4

2

0

High-throughput

0.580

High

1019240

HYAL2
Hyaluronidase-2

2

0

High-throughput

0.580

High

1023345

TRI32
E3 ubiquitin-protein ligase TRIM32

2

0

High-throughput

0.580

High

1334830

LZTL1
Leucine zipper transcription factor-like protein 1

2

0

High-throughput

0.580

High

1302051

SRPK1
SRSF protein kinase 1

1

2

High-throughput

0.569

High

1170211

CL17A
C-type lectin domain family 17, member A

2

1

High-throughput

0.553

High

1330000

P63
Tumor protein 63

2

3

High-throughput

0.553

High

724566

IRS1
Insulin receptor substrate 1

1

1

Small-scale

0.552

High

1334831

UBQL4
Ubiquilin-4

1

0

High-throughput

0.518

High

197917

IRAK2
Interleukin-1 receptor-associated kinase-like 2

1

11

Small-scale

0.479

High

602874

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

0

Small-scale

0.460

High

1036484

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

0

High-throughput

0.460

High

1138041

RN220
E3 ubiquitin-protein ligase RNF220

1

0

Small-scale

0.460

High

1147416

CR3L3
Cyclic AMP-responsive element-binding protein 3-like protein 3

1

0

High-throughput

0.460

High

1334829

MYO10
Unconventional myosin-X

1

0

Small-scale

0.460

High

263447

DEAF1
Deformed epidermal autoregulatory factor 1 homolog

1

1

High-throughput

0.439

High

1305786

CTIP
DNA endonuclease RBBP8

1

1

Small-scale

0.439

High

815447

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

1

Small-scale

0.437

High

824395

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

Small-scale

0.437

High

387540

P53
Cellular tumor antigen p53

1

3

Small-scale

0.408

High

1334838

ROBO1
Roundabout homolog 1

2

0

Small-scale

0.323

High

718430

PCGF2
Polycomb group RING finger protein 2

2

0

High-throughput

0.316

High

837849

MEOX1
Homeobox protein MOX-1

2

0

High-throughput

0.316

High

1070170

RABE1
Rab GTPase-binding effector protein 1

2

0

High-throughput

0.316

High

1300753

OR7D2
Olfactory receptor 7D2

2

0

High-throughput

0.316

High

1303165

RMD3
Regulator of microtubule dynamics protein 3

2

0

High-throughput

0.316

High

1306251

MDFI
MyoD family inhibitor

2

0

High-throughput

0.316

High

1311057

TMM79
Transmembrane protein 79

2

0

High-throughput

0.316

High

1334834

SEPT3
Neuronal-specific septin-3

2

0

High-throughput

0.316

High

280073

MPDZ
Multiple PDZ domain protein

1

0

Small-scale

0.251

Low

300503

FRYL
Protein furry homolog-like

1

0

High-throughput

0.251

Low

363302

FINC
Fibronectin

1

0

High-throughput

0.251

Low

904144

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

0

High-throughput

0.251

Low

1293474

ERO1A
ERO1-like protein alpha

1

0

High-throughput

0.251

Low

1311835

THAP7
THAP domain-containing protein 7

1

0

High-throughput

0.251

Low

1334832

LTBP3
Latent-transforming growth factor beta-binding protein 3

1

0

High-throughput

0.251

Low

1334835

C170B
Centrosomal protein of 170 kDa protein B

1

0

Small-scale

0.251

Low

1334837

LAMC3
Laminin subunit gamma-3

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024