Protein: DEN1A
DENN domain-containing protein 1A (Connecdenn 1) (Connecdenn) (Protein FAM31A)

Gene: DEN1A, DENND1A
Organism: Homo sapiens
Interactions: 99
UniProt ID: Q8TEH3

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0006897 - endocytosis
GO:0015031 - protein transport
GO:0030136 - clathrin-coated vesicle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1139618

DEN4C
DENN domain-containing protein 4C

1

5

High-throughput

0.618

High

1189722

MYCPP
C-myc promoter-binding protein

1

5

High-throughput

0.618

High

1256269

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

4

High-throughput

0.618

High

683566

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.611

High

909848

1433E
14-3-3 protein epsilon

2

7

High-throughput

0.611

High

927335

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.611

High

1256264

LIMA1
LIM domain and actin-binding protein 1

2

2

High-throughput

0.611

High

370070

ESR1
Estrogen receptor

2

11

High-throughput

0.571

High

1153302

PKHA7
Pleckstrin homology domain-containing family A member 7

2

8

High-throughput

0.571

High

904903

1433G
14-3-3 protein gamma

1

20

High-throughput

0.554

High

982314

1433F
14-3-3 protein eta

1

20

High-throughput

0.554

High

161692

GAK
Cyclin-G-associated kinase

1

2

High-throughput

0.536

High

451710

CLCB
Clathrin light chain B

1

1

High-throughput

0.536

High

960898

CLH1
Clathrin heavy chain 1

1

1

High-throughput

0.536

High

1036445

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

4

High-throughput

0.536

High

887588

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

1256260

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.513

High

574717

ARF4
ADP-ribosylation factor 4

1

7

Small-scale

0.501

High

950528

ARF1
ADP-ribosylation factor 1

1

7

Small-scale

0.501

High

306835

VAMP5
Vesicle-associated membrane protein 5

1

4

High-throughput

0.489

High

163041

XPO1
Exportin-1

1

4

High-throughput

0.479

High

237275

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

2

High-throughput

0.479

High

253383

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

3

High-throughput

0.479

High

264365

GGYF1
GRB10-interacting GYF protein 1

1

5

High-throughput

0.479

High

316268

NADK
NAD kinase

1

1

High-throughput

0.479

High

374585

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

7

High-throughput

0.479

High

451511

CLCA
Clathrin light chain A

1

1

High-throughput

0.479

High

598505

NF1
Neurofibromin

1

7

High-throughput

0.479

High

647133

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

673503

MPIP2
M-phase inducer phosphatase 2

1

3

High-throughput

0.479

High

673610

MPIP3
M-phase inducer phosphatase 3

1

3

High-throughput

0.479

High

684226

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

876451

AFAD
Afadin

1

11

High-throughput

0.479

High

880790

HDAC4
Histone deacetylase 4

1

8

High-throughput

0.479

High

925954

AP2B1
AP-2 complex subunit beta

1

2

High-throughput

0.479

High

960393

CDK16
Cyclin-dependent kinase 16

1

2

High-throughput

0.479

High

997194

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

3

High-throughput

0.479

High

1020195

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

7

High-throughput

0.479

High

1022425

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

2

High-throughput

0.479

High

1060577

ZN638
Zinc finger protein 638

1

2

High-throughput

0.479

High

1136529

SPD2A
SH3 and PX domain-containing protein 2A

1

7

High-throughput

0.479

High

1162618

LARP1
La-related protein 1

1

1

High-throughput

0.479

High

1167935

GGYF2
GRB10-interacting GYF protein 2

1

7

High-throughput

0.479

High

1185253

RFIP2
Rab11 family-interacting protein 2

1

5

High-throughput

0.479

High

1188319

ATG9A
Autophagy-related protein 9A

1

2

High-throughput

0.479

High

1197814

PHLB2
Pleckstrin homology-like domain family B member 2

1

3

High-throughput

0.479

High

1203938

RGPS2
Ras-specific guanine nucleotide-releasing factor RalGPS2

1

2

High-throughput

0.479

High

1217965

KSR1
Kinase suppressor of Ras 1

1

5

High-throughput

0.479

High

1229998

RPTOR
Regulatory-associated protein of mTOR

1

3

High-throughput

0.479

High

1253327

F110B
Protein FAM110B

1

3

High-throughput

0.479

High

1256241

HDAC7
Histone deacetylase 7

1

8

High-throughput

0.479

High

1256246

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

7

High-throughput

0.479

High

1256248

SIN1
Target of rapamycin complex 2 subunit MAPKAP1

1

1

High-throughput

0.479

High

1256249

F110A
Protein FAM110A

1

3

High-throughput

0.479

High

1256251

RTKN
Rhotekin

1

2

High-throughput

0.479

High

1256252

OSBL6
Oxysterol-binding protein-related protein 6

1

1

High-throughput

0.479

High

1256255

PKHA5
Pleckstrin homology domain-containing family A member 5

1

11

High-throughput

0.479

High

1256258

INP5E
Phosphatidylinositol polyphosphate 5-phosphatase type IV

1

2

High-throughput

0.479

High

1256265

NGAP
Ras GTPase-activating protein nGAP

1

7

High-throughput

0.479

High

1256266

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

1

High-throughput

0.479

High

1256267

ZBT21
Zinc finger and BTB domain-containing protein 21

1

2

High-throughput

0.479

High

1256270

GAB2
GRB2-associated-binding protein 2

1

6

High-throughput

0.479

High

1256271

CBY1
Protein chibby homolog 1

1

2

High-throughput

0.479

High

1256272

STA13
StAR-related lipid transfer protein 13

1

6

High-throughput

0.479

High

1068831

PCM1
Pericentriolar material 1 protein

1

0

High-throughput

0.460

High

154219

CHK1
Serine/threonine-protein kinase Chk1

1

0

High-throughput

0.458

High

1256244

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.458

High

1256261

SH3B4
SH3 domain-binding protein 4

1

0

High-throughput

0.458

High

950665

ARF5
ADP-ribosylation factor 5

1

7

Small-scale

0.457

High

1256245

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

7

High-throughput

0.445

High

166588

DCLK1
Serine/threonine-protein kinase DCLK1

1

3

High-throughput

0.437

High

196481

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

4

High-throughput

0.437

High

216951

KIF1C
Kinesin-like protein KIF1C

1

6

High-throughput

0.437

High

230896

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

5

High-throughput

0.437

High

231648

KIF1B
Kinesin-like protein KIF1B

1

6

High-throughput

0.437

High

569894

CEBPB
CCAAT/enhancer-binding protein beta

1

2

High-throughput

0.437

High

1057183

MELK
Maternal embryonic leucine zipper kinase

1

1

High-throughput

0.437

High

1076898

PTN14
Tyrosine-protein phosphatase non-receptor type 14

1

7

High-throughput

0.437

High

1109678

TBC25
TBC1 domain family member 25

1

1

High-throughput

0.437

High

1136466

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

5

High-throughput

0.437

High

1148995

AN34A
Ankyrin repeat domain-containing protein 34A

1

4

High-throughput

0.437

High

1173133

SYDE1
Rho GTPase-activating protein SYDE1

1

7

High-throughput

0.437

High

1243662

NAV1
Neuron navigator 1

1

5

High-throughput

0.437

High

1256240

SH3R3
E3 ubiquitin-protein ligase SH3RF3

1

8

High-throughput

0.437

High

1256242

DEP1B
DEP domain-containing protein 1B

1

2

High-throughput

0.437

High

1256243

SRS12
Serine/arginine-rich splicing factor 12

1

2

High-throughput

0.437

High

1256247

TESK2
Dual specificity testis-specific protein kinase 2

1

3

High-throughput

0.437

High

1256250

LPIN3
Phosphatidate phosphatase LPIN3

1

1

High-throughput

0.437

High

1256256

TANC2
Protein TANC2

1

2

High-throughput

0.437

High

1256257

KI13B
Kinesin-like protein KIF13B

1

6

High-throughput

0.437

High

1256259

FA53C
Protein FAM53C

1

1

High-throughput

0.437

High

1256262

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

3

High-throughput

0.437

High

1256263

CING
Cingulin

1

3

High-throughput

0.437

High

1256268

PPM1H
Protein phosphatase 1H

1

3

High-throughput

0.437

High

1256273

KCTD3
BTB/POZ domain-containing protein KCTD3

1

2

High-throughput

0.437

High

1245524

ATLA2
Atlastin-2

1

0

High-throughput

0.279

Low

1256254

PAAT
ATPase PAAT

1

0

High-throughput

0.279

Low

959558

VIGLN
Vigilin

1

0

High-throughput

0.249

Low

1256253

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024