Protein: AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (AGAP-1) (Centaurin-gamma-2) (Cnt-g2) (GTP-binding and GTPase-activating protein 1) (GGAP1)

Gene: AGAP1
Organism: Homo sapiens
Interactions: 113
UniProt ID: Q9UPQ3

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005096 - GTPase activator activity
GO:0005525 - GTP binding
GO:0005543 - phospholipid binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

913191

ARF6
ADP-ribosylation factor 6

3

17

Small-scale

0.834

High

950579

ARF1
ADP-ribosylation factor 1

2

17

Small-scale

0.799

High

901056

RHOA
Transforming protein RhoA

1

20

Small-scale

0.724

High

1072629

EPHA7
Ephrin type-A receptor 7

2

10

High-throughput

0.705

High

1044276

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

5

High-throughput

0.698

High

1299064

AGAP3
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

1

13

High-throughput

0.691

High

1231972

MIER2
Mesoderm induction early response protein 2

3

3

High-throughput

0.656

High

1310649

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

3

4

High-throughput

0.656

High

523208

SRC
Proto-oncogene tyrosine-protein kinase Src

1

15

Small-scale

0.647

High

894593

CDC42
Cell division control protein 42 homolog

1

20

Small-scale

0.647

High

925736

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

Small-scale

0.647

High

1357702

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

14

Small-scale

0.647

High

1319205

TANC1
Protein TANC1

1

10

High-throughput

0.618

High

1335969

TANC2
Protein TANC2

1

9

High-throughput

0.618

High

1357705

E41L3
Band 4.1-like protein 3

1

12

High-throughput

0.618

High

163473

XPO1
Exportin-1

1

7

High-throughput

0.618

High

196531

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

6

High-throughput

0.618

High

230932

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

14

High-throughput

0.618

High

253433

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

8

High-throughput

0.618

High

349009

RASN
GTPase NRas

1

20

High-throughput

0.618

High

350689

RASK
GTPase KRas

1

20

High-throughput

0.618

High

598546

NF1
Neurofibromin

1

20

High-throughput

0.618

High

881576

ARL4C
ADP-ribosylation factor-like protein 4C

1

20

High-throughput

0.618

High

960426

CDK16
Cyclin-dependent kinase 16

1

1

High-throughput

0.618

High

1057213

MELK
Maternal embryonic leucine zipper kinase

1

1

High-throughput

0.618

High

1070459

RAB35
Ras-related protein Rab-35

1

12

High-throughput

0.618

High

1109702

TBC25
TBC1 domain family member 25

1

4

High-throughput

0.618

High

1136494

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

3

High-throughput

0.618

High

1136563

SPD2A
SH3 and PX domain-containing protein 2A

1

20

High-throughput

0.618

High

1139653

DEN4C
DENN domain-containing protein 4C

1

4

High-throughput

0.618

High

1172285

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.618

High

1173164

SYDE1
Rho GTPase-activating protein SYDE1

1

9

High-throughput

0.618

High

1256269

DEN1A
DENN domain-containing protein 1A

1

4

High-throughput

0.618

High

1260800

DEP1B
DEP domain-containing protein 1B

1

8

High-throughput

0.618

High

1300695

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

18

High-throughput

0.618

High

1308735

SIN1
Target of rapamycin complex 2 subunit MAPKAP1

1

2

High-throughput

0.618

High

1318256

KPCD2
Serine/threonine-protein kinase D2

1

20

High-throughput

0.618

High

1343635

KI13B
Kinesin-like protein KIF13B

1

3

High-throughput

0.618

High

1355280

LIMA1
LIM domain and actin-binding protein 1

1

10

High-throughput

0.618

High

1355995

NGAP
Ras GTPase-activating protein nGAP

1

20

High-throughput

0.618

High

1357703

GAB2
GRB2-associated-binding protein 2

1

9

High-throughput

0.618

High

1244380

FLCN
Folliculin

2

3

High-throughput

0.611

High

1176238

ZN534
Zinc finger protein 534

2

1

High-throughput

0.606

High

1054113

GRB7
Growth factor receptor-bound protein 7

1

20

High-throughput

0.587

High

1300450

RAB3I
Rab-3A-interacting protein

1

0

High-throughput

0.586

High

1311611

RTKN
Rhotekin

1

0

High-throughput

0.586

High

1349860

SH3B4
SH3 domain-binding protein 4

1

0

High-throughput

0.586

High

370721

ESR1
Estrogen receptor

2

4

High-throughput

0.571

High

1190534

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

2

3

High-throughput

0.558

High

1236767

PCD20
Protocadherin-20

2

8

High-throughput

0.558

High

1310218

LZTS2
Leucine zipper putative tumor suppressor 2

2

7

High-throughput

0.558

High

1357422

PCDAC
Protocadherin alpha-12

2

3

High-throughput

0.558

High

1355529

RSP14
Radial spoke head 14 homolog

2

3

High-throughput

0.553

High

166632

DCLK1
Serine/threonine-protein kinase DCLK1

1

13

High-throughput

0.553

High

216990

KIF1C
Kinesin-like protein KIF1C

1

3

High-throughput

0.553

High

793530

MUC18
Cell surface glycoprotein MUC18

1

4

High-throughput

0.553

High

876539

AFAD
Afadin

1

15

High-throughput

0.553

High

1022473

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

17

High-throughput

0.553

High

1149013

AN34A
Ankyrin repeat domain-containing protein 34A

1

18

High-throughput

0.553

High

1153457

PKHA7
Pleckstrin homology domain-containing family A member 7

1

12

High-throughput

0.553

High

1197855

PHLB2
Pleckstrin homology-like domain family B member 2

1

7

High-throughput

0.553

High

1334860

PKHA5
Pleckstrin homology domain-containing family A member 5

1

17

High-throughput

0.553

High

1350026

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

1

High-throughput

0.553

High

647382

1433T
14-3-3 protein theta

1

20

High-throughput

0.536

High

683815

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.536

High

905263

1433G
14-3-3 protein gamma

1

20

High-throughput

0.536

High

910161

1433E
14-3-3 protein epsilon

1

7

High-throughput

0.536

High

927661

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

982623

1433F
14-3-3 protein eta

1

20

High-throughput

0.536

High

1216306

ZNG1B
Zinc-regulated GTPase metalloprotein activator 1B

1

4

High-throughput

0.536

High

1219117

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

1283607

TRI52
E3 ubiquitin-protein ligase TRIM52

1

3

High-throughput

0.536

High

969025

GCYA1
Guanylate cyclase soluble subunit alpha-1

1

0

Small-scale

0.529

High

862317

NUBP1
Cytosolic Fe-S cluster assembly factor NUBP1

1

0

High-throughput

0.513

High

396059

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

146732

NCKP5
Nck-associated protein 5

1

10

High-throughput

0.489

High

197109

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

1

5

High-throughput

0.489

High

672756

CD6
T-cell differentiation antigen CD6

1

1

High-throughput

0.489

High

1252910

ZCH10
Zinc finger CCHC domain-containing protein 10

1

1

High-throughput

0.489

High

1329032

CAD23
Cadherin-23

1

1

High-throughput

0.489

High

1084937

SMN
Survival motor neuron protein

1

0

High-throughput

0.486

High

229072

PRKN
E3 ubiquitin-protein ligase parkin

1

9

High-throughput

0.479

High

780331

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

880857

HDAC4
Histone deacetylase 4

1

6

High-throughput

0.479

High

1037006

SQSTM
Sequestosome-1

1

6

Small-scale

0.479

High

1218001

KSR1
Kinase suppressor of Ras 1

1

18

High-throughput

0.479

High

1243702

NAV1
Neuron navigator 1

1

8

High-throughput

0.479

High

1263479

SRS12
Serine/arginine-rich splicing factor 12

1

1

High-throughput

0.479

High

1301725

TESK2
Dual specificity testis-specific protein kinase 2

1

3

High-throughput

0.479

High

1356318

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

1

High-throughput

0.479

High

1356892

ZBT21
Zinc finger and BTB domain-containing protein 21

1

2

High-throughput

0.479

High

1356974

PPM1H
Protein phosphatase 1H

1

1

High-throughput

0.479

High

237345

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

0

High-throughput

0.458

High

316290

NADK
NAD kinase

1

0

High-throughput

0.458

High

673537

MPIP2
M-phase inducer phosphatase 2

1

0

High-throughput

0.458

High

1060651

ZN638
Zinc finger protein 638

1

0

High-throughput

0.458

High

497809

TAU
Microtubule-associated protein tau

1

14

High-throughput

0.445

High

264442

GGYF1
GRB10-interacting GYF protein 1

1

1

High-throughput

0.437

High

997239

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

4

High-throughput

0.437

High

1253347

F110B
Protein FAM110B

1

1

High-throughput

0.437

High

1309185

F110A
Protein FAM110A

1

1

High-throughput

0.437

High

1357707

KCTD3
BTB/POZ domain-containing protein KCTD3

1

2

High-throughput

0.437

High

1357708

PCDAA
Protocadherin alpha-10

1

3

High-throughput

0.437

High

240271

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.407

High

1174788

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

1

1

High-throughput

0.407

High

1357704

ITM2B
Integral membrane protein 2B

1

2

High-throughput

0.407

High

867488

ICLN
Methylosome subunit pICln

1

0

High-throughput

0.279

Low

378792

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.265

Low

1291009

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.249

Low

1348459

FA53C
Protein FAM53C

1

0

High-throughput

0.249

Low

1350453

CING
Cingulin

1

0

High-throughput

0.249

Low

1357706

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024