Protein: DHB8
(3R)-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12) (17-beta-hydroxysteroid dehydrogenase 8) (17-beta-HSD 8) (HSD17B8) (3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit) (KAR alpha subunit) (3-oxoacyl-[acyl-carrier-protein] reductase) (Estradiol 17-beta-dehydrogenase 8) (EC 1.1.1.62) (Protein Ke6) (Ke6) (Short chain dehydrogenase/reductase family 30C member 1) (Testosterone 17-beta-dehydrogenase 8) (EC 1.1.1.239)

Gene: DHB8, HSD17B8
Organism: Homo sapiens
Interactions: 33
UniProt ID: Q92506

Gene Ontology (top 5):
GO:0004303 - estradiol 17-beta-dehydrogenase [NAD(P)+] activity
GO:0005740 - mitochondrial envelope
GO:0005759 - mitochondrial matrix
GO:0005886 - plasma membrane
GO:0006633 - fatty acid biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1233869

CBR4
3-oxoacyl-[acyl-carrier-protein] reductase

3

16

High-throughput

0.861

High

855155

HNRPF
Heterogeneous nuclear ribonucleoprotein F

2

5

High-throughput

0.628

High

803171

IF2M
Translation initiation factor IF-2, mitochondrial

3

4

High-throughput

0.609

High

1266234

MOCOS
Molybdenum cofactor sulfurase

3

1

High-throughput

0.609

High

1266241

SEPT3
Neuronal-specific septin-3

3

1

High-throughput

0.609

High

1086689

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

3

High-throughput

0.584

High

520729

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

1

5

High-throughput

0.536

High

829308

SYHM
Histidine--tRNA ligase, mitochondrial

1

3

High-throughput

0.536

High

1064940

SYLM
Leucine--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

1121859

BOLA3
BolA-like protein 3

1

1

High-throughput

0.536

High

1266236

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

2

High-throughput

0.536

High

993114

CP24A
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

1

1

High-throughput

0.489

High

1218860

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.489

High

1068027

PDK1
[Pyruvate dehydrogenase

1

2

High-throughput

0.479

High

1266243

RT02
Small ribosomal subunit protein uS2m

1

0

High-throughput

0.458

High

1251872

RIN3
Ras and Rab interactor 3

1

2

High-throughput

0.437

High

1266233

ESR2
Estrogen receptor beta

1

6

High-throughput

0.437

High

587649

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

1

High-throughput

0.407

High

1124794

OXLD1
Oxidoreductase-like domain-containing protein 1

3

0

High-throughput

0.347

High

1139316

SUSD4
Sushi domain-containing protein 4

3

0

High-throughput

0.347

High

1266235

ZN414
Zinc finger protein 414

3

0

High-throughput

0.347

High

215849

ANGL7
Angiopoietin-related protein 7

2

0

High-throughput

0.328

High

1190912

TAFA3
Chemokine-like protein TAFA-3

2

0

High-throughput

0.328

High

154620

TPP1
Tripeptidyl-peptidase 1

1

0

High-throughput

0.279

Low

551223

ITF2
Transcription factor 4

1

0

High-throughput

0.279

Low

1266238

BEX4
Protein BEX4

1

0

High-throughput

0.279

Low

1266239

RBX2
RING-box protein 2

1

0

High-throughput

0.279

Low

1266240

CS025
UPF0449 protein C19orf25

1

0

High-throughput

0.279

Low

1266242

AT7L1
Ataxin-7-like protein 1

1

0

High-throughput

0.279

Low

224491

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.249

Low

1201855

TAXB1
Tax1-binding protein 1

1

0

High-throughput

0.249

Low

1266244

RT23
Small ribosomal subunit protein mS23

1

0

High-throughput

0.249

Low

1266237

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024