Protein: DHSO
Sorbitol dehydrogenase (SDH) (EC 1.1.1.-) ((R,R)-butanediol dehydrogenase) (EC 1.1.1.4) (L-iditol 2-dehydrogenase) (EC 1.1.1.14) (Polyol dehydrogenase) (Ribitol dehydrogenase) (RDH) (EC 1.1.1.56) (Xylitol dehydrogenase) (XDH) (EC 1.1.1.9)

Gene: DHSO, SORD
Organism: Homo sapiens
Interactions: 49
UniProt ID: Q00796

Gene Ontology (top 5):
GO:0000721 - (R,R)-butanediol dehydrogenase activity
GO:0003939 - L-iditol 2-dehydrogenase (NAD+) activity
GO:0005615 - extracellular space
GO:0005829 - cytosol
GO:0006006 - glucose metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

961970

DHSO
Sorbitol dehydrogenase

6

15

High-throughput

0.943

High

961985

PRR11
Proline-rich protein 11

3

0

High-throughput

0.638

High

227188

PRKN
E3 ubiquitin-protein ligase parkin

2

10

High-throughput

0.584

High

961971

KPCE
Protein kinase C epsilon type

2

1

High-throughput

0.571

High

961978

KPCD1
Serine/threonine-protein kinase D1

2

1

High-throughput

0.571

High

961972

CAV1
Caveolin-1

2

0

High-throughput

0.547

High

874831

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.515

High

571113

EGLN
Endoglin

1

0

High-throughput

0.513

High

724780

MYH9
Myosin-9

1

0

High-throughput

0.513

High

961989

ANLN
Anillin

1

0

High-throughput

0.513

High

961990

PDLI7
PDZ and LIM domain protein 7

1

0

High-throughput

0.513

High

961976

KLF9
Krueppel-like factor 9

1

0

High-throughput

0.479

High

329644

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.479

High

456851

FURIN
Furin

1

1

High-throughput

0.479

High

475637

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

9

High-throughput

0.479

High

923643

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

1

High-throughput

0.479

High

923959

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

5

High-throughput

0.479

High

924275

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

5

High-throughput

0.479

High

961974

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.479

High

961982

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

961992

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

380952

SHBG
Sex hormone-binding globulin

1

0

Small-scale

0.460

High

961973

TF65
Transcription factor p65

1

0

High-throughput

0.460

High

155332

NRP1
Neuropilin-1

1

0

High-throughput

0.458

High

351747

SOMA
Somatotropin

1

0

High-throughput

0.458

High

352069

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.458

High

575376

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

714818

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

0

High-throughput

0.458

High

726154

BASI
Basigin

1

0

High-throughput

0.458

High

961975

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

961977

ZN638
Zinc finger protein 638

1

0

High-throughput

0.458

High

961983

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

961984

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

961986

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

961987

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

961993

TNIK
TRAF2 and NCK-interacting protein kinase

1

0

High-throughput

0.458

High

961980

PKHA7
Pleckstrin homology domain-containing family A member 7

1

2

High-throughput

0.445

High

961981

NBEL2
Neurobeachin-like protein 2

1

1

High-throughput

0.445

High

244294

BRD4
Bromodomain-containing protein 4

1

5

High-throughput

0.437

High

552511

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

650976

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

720246

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

961988

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

961979

SPAT1
Spermatogenesis-associated protein 1

1

0

High-throughput

0.279

Low

961991

CFA97
Cilia- and flagella-associated protein 97

1

0

High-throughput

0.279

Low

346540

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

384659

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

831224

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.213

Low


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Last updated: 15 Jul 2024