Protein: GDF8
Growth/differentiation factor 8 (GDF-8) (Myostatin)

Gene: GDF8, MSTN
Organism: Homo sapiens
Interactions: 33
UniProt ID: O14793

Gene Ontology (top 5):
GO:0005102 - signaling receptor binding
GO:0005125 - cytokine activity
GO:0005615 - extracellular space
GO:0007179 - transforming growth factor beta receptor signaling pathway
GO:0007517 - muscle organ development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

155744

GDF8
Growth/differentiation factor 8

2

16

Small-scale

0.849

High

155747

FSTL3
Follistatin-related protein 3

1

9

Small-scale

0.724

High

155757

AVR2B
Activin receptor type-2B

2

20

Small-scale

0.702

High

155745

GDF11
Growth/differentiation factor 11

1

17

High-throughput

0.691

High

155759

PRTG
Protogenin

1

2

High-throughput

0.691

High

155769

GDF15
Growth/differentiation factor 15

1

16

High-throughput

0.691

High

155752

BMP1
Bone morphogenetic protein 1

3

12

Small-scale

0.664

High

155750

FURIN
Furin

2

3

Small-scale

0.602

High

155768

WFKN1
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1

1

13

Small-scale

0.536

High

155751

CO6A2

1

7

High-throughput

0.536

High

155755

PCSK6
Proprotein convertase subtilisin/kexin type 6

1

9

High-throughput

0.536

High

155758

GAS6
Growth arrest-specific protein 6

1

13

High-throughput

0.536

High

155760

METRL
Meteorin-like protein

1

1

High-throughput

0.536

High

155764

VWDE
von Willebrand factor D and EGF domain-containing protein

1

4

High-throughput

0.536

High

155766

PCSK9
Proprotein convertase subtilisin/kexin type 9

1

3

High-throughput

0.536

High

155775

JAG2
Protein jagged-2

1

3

High-throughput

0.536

High

155749

A4
Amyloid-beta precursor protein

1

18

High-throughput

0.501

High

155746

ATS2
A disintegrin and metalloproteinase with thrombospondin motifs 2

1

5

High-throughput

0.489

High

155748

OXSR1
Serine/threonine-protein kinase OSR1

1

2

High-throughput

0.489

High

155756

LAMB2
Laminin subunit beta-2

1

5

High-throughput

0.489

High

155762

PLGT2
Protein O-glucosyltransferase 2

1

1

High-throughput

0.489

High

155763

MEGF8
Multiple epidermal growth factor-like domains protein 8

1

6

High-throughput

0.489

High

155765

PGLT1
Protein O-glucosyltransferase 1

1

1

High-throughput

0.489

High

155767

APBP2
Amyloid protein-binding protein 2

1

1

High-throughput

0.489

High

155770

CELR1
Cadherin EGF LAG seven-pass G-type receptor 1

1

4

High-throughput

0.489

High

155772

KLH42
Kelch-like protein 42

1

1

High-throughput

0.489

High

155773

ADA21
Disintegrin and metalloproteinase domain-containing protein 21

1

4

High-throughput

0.489

High

155774

ATS7
A disintegrin and metalloproteinase with thrombospondin motifs 7

1

5

High-throughput

0.489

High

155753

PERF
Perforin-1

1

0

High-throughput

0.279

Low

155754

ZNF24
Zinc finger protein 24

1

0

High-throughput

0.279

Low

155761

UTP25
U3 small nucleolar RNA-associated protein 25 homolog

1

0

High-throughput

0.279

Low

155771

CHPF2
Chondroitin sulfate glucuronyltransferase

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024