Protein: IMA2
Importin subunit alpha-2 (Importin-1) (Karyopherin subunit alpha-2)

Gene: IMA2, imp1
Organism: Schizosaccharomyces pombe 972h-
Interactions: 124
UniProt ID: O94374

Gene Ontology (top 5):
GO:0005525 - GTP binding
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

151868

IMB1
Importin subunit beta-1

1

20

Small-scale

0.618

High

152691

IMA1
Importin subunit alpha-1

1

8

Small-scale

0.618

High

152746

IMB2
Importin subunit beta-2

1

20

Small-scale

0.618

High

313951

IMA2
Importin subunit alpha-2

1

8

Small-scale

0.618

High

314012

NUP61
Nucleoporin nup61

1

20

Small-scale

0.618

High

237826

TDG
G/U mismatch-specific uracil DNA glycosylase

2

1

Small-scale

0.586

High

238219

BQT4
Bouquet formation protein 4

2

1

Small-scale

0.584

High

206127

YFHE
Uncharacterized trans-sulfuration enzyme C23A1.14c

1

3

High-throughput

0.515

High

237741

ESS2
Stress response protein bis1

1

1

Small-scale

0.508

High

152035

GLY1
Probable low-specificity L-threonine aldolase

1

0

High-throughput

0.493

High

152615

PDX1
Probable pyridoxal 5'-phosphate synthase subunit PDX1

1

1

High-throughput

0.481

High

154057

CBH1
CENP-B homolog protein 1

1

3

High-throughput

0.481

High

205985

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

4

High-throughput

0.481

High

238020

CBH2
CENP-B homolog protein 2

1

3

High-throughput

0.481

High

238096

YH7G
Putative transcriptional regulatory protein C16G5.16

1

1

High-throughput

0.481

High

313547

CAN
Carbonic anhydrase

1

1

High-throughput

0.481

High

313924

ASSY
Argininosuccinate synthase

1

1

High-throughput

0.481

High

313956

ADN2
Adhesion defective protein 2

1

3

High-throughput

0.481

High

313957

SIR2
NAD-dependent histone deacetylase sir2

1

7

High-throughput

0.481

High

313972

THI6
Probable thiamine biosynthetic bifunctional enzyme [Includes: Thiamine-phosphate synthase

1

1

High-throughput

0.481

High

313979

CDD
Putative cytidine deaminase

1

2

High-throughput

0.481

High

313981

PANB
Probable 3-methyl-2-oxobutanoate hydroxymethyltransferase

1

1

High-throughput

0.481

High

313982

HSP32
Glutathione-independent glyoxalase hsp3102

1

1

High-throughput

0.481

High

313986

MTAP
S-methyl-5'-thioadenosine phosphorylase

1

1

High-throughput

0.481

High

313997

ARGI2
Arginase

1

1

High-throughput

0.481

High

314002

UPP2
Uracil phosphoribosyltransferase 2

1

1

High-throughput

0.481

High

314006

SEC18
Vesicular-fusion protein sec18

1

3

High-throughput

0.481

High

314009

ALP7
Microtubule protein alp7

1

1

High-throughput

0.481

High

314010

SAT
Putative serine acetyltransferase

1

1

High-throughput

0.481

High

314016

NMAH
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase

1

7

High-throughput

0.481

High

149405

DED1
ATP-dependent RNA helicase ded1

1

2

Small-scale

0.479

High

151499

YE02
Uncharacterized helicase C17H9.02

1

2

High-throughput

0.479

High

151676

DRI1
RNA-binding protein involved in heterochromatin assembly dri1

1

18

Small-scale

0.479

High

152733

RPA49
DNA-directed RNA polymerase I subunit rpa49

1

3

Small-scale

0.479

High

152921

PRS6A
26S proteasome regulatory subunit 6A

1

5

Small-scale

0.479

High

153831

RLA6
Large ribosomal subunit protein P2C

1

1

Small-scale

0.479

High

153834

PHP4
CCAAT-binding factor complex subunit php4

1

1

Small-scale

0.479

High

153996

HSP16
Heat shock protein 16

1

7

Small-scale

0.479

High

237564

CLR6
Histone deacetylase clr6

1

13

Small-scale

0.479

High

237770

YCO6
Putative nucleosome assembly protein C364.06

1

1

Small-scale

0.479

High

238245

PESC
Pescadillo homolog

1

1

Small-scale

0.479

High

267646

PRS10
Probable 26S proteasome subunit rpt4

1

5

Small-scale

0.479

High

267997

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

2

Small-scale

0.479

High

268103

YOU5
Putative serine/threonine-protein phosphatase C26H8.05c

1

6

Small-scale

0.479

High

268113

GRN1
GTPase grn1

1

2

Small-scale

0.479

High

268308

RL1B
Large ribosomal subunit protein uL1B

1

1

Small-scale

0.479

High

268793

FAT2
Oxalate--CoA ligase

1

1

Small-scale

0.479

High

313595

NOP2
25S rRNA

1

1

Small-scale

0.479

High

313671

YH56
UPF0743 protein C215.06c

1

4

Small-scale

0.479

High

313952

EF3
Elongation factor 3

1

2

Small-scale

0.479

High

313953

NOP56
Nucleolar protein 56

1

14

Small-scale

0.479

High

313954

FOR3
Formin-3

1

1

Small-scale

0.479

High

313955

MU184
Meiotically up-regulated gene 184 protein

1

1

Small-scale

0.479

High

313959

NOG1
Probable nucleolar GTP-binding protein 1

1

1

Small-scale

0.479

High

313962

ADH
Alcohol dehydrogenase

1

1

Small-scale

0.479

High

313964

RLA2
Large ribosomal subunit protein P2A

1

1

Small-scale

0.479

High

313965

H4
Histone H4

1

1

Small-scale

0.479

High

313966

RS27B
Ubiquitin-ribosomal protein eS31B fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31B

1

3

Small-scale

0.479

High

313967

RPA1
DNA-directed RNA polymerase I subunit rpa1

1

1

Small-scale

0.479

High

313968

RLA3
Large ribosomal subunit protein P1B

1

2

Small-scale

0.479

High

313974

TCPD
T-complex protein 1 subunit delta

1

1

Small-scale

0.479

High

313977

AP1
AP-1-like transcription factor

1

1

Small-scale

0.479

High

313984

THO2
THO complex subunit 2

1

7

Small-scale

0.479

High

313990

HOG1
Mitogen-activated protein kinase sty1

1

2

Small-scale

0.479

High

313991

DRS1
ATP-dependent RNA helicase drs1

1

5

Small-scale

0.479

High

313992

NU124
Nucleoporin nup124

1

20

Small-scale

0.479

High

313994

HAS1
ATP-dependent RNA helicase has1

1

6

Small-scale

0.479

High

313998

HSP71
Probable heat shock protein ssa1

1

3

Small-scale

0.479

High

314004

CDC48
Cell division cycle protein 48

1

1

Small-scale

0.479

High

314005

ACON2
Aconitase-ribosomal protein bL21m fusion protein [Includes: Homocitrate dehydratase, mitochondrial

1

1

Small-scale

0.479

High

314008

RL31
Large ribosomal subunit protein eL31

1

1

Small-scale

0.479

High

314011

YJQ1
Uncharacterized ABC transporter ATP-binding protein C825.01

1

2

Small-scale

0.479

High

314015

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

5

Small-scale

0.479

High

314019

RLA5
Large ribosomal subunit protein P1C

1

2

Small-scale

0.479

High

152197

NDC1
Nuclear envelope protein ndc1

1

0

High-throughput

0.460

High

205915

DMC1
Meiotic recombination protein dmc1

1

0

High-throughput

0.460

High

237594

YBH8
Uncharacterized protein C3B8.8

1

0

High-throughput

0.460

High

313913

DHYS
Probable deoxyhypusine synthase

1

0

High-throughput

0.460

High

313961

TAS3
RNA-induced transcriptional silencing complex protein tas3

1

0

High-throughput

0.460

High

313970

KAPR
cAMP-dependent protein kinase regulatory subunit

1

0

High-throughput

0.460

High

313971

HIS1
ATP phosphoribosyltransferase

1

0

High-throughput

0.460

High

313983

YA55
Putative aminopeptidase C13A11.05

1

0

High-throughput

0.460

High

313993

ALLC
Probable allantoicase

1

0

High-throughput

0.460

High

313995

YAKA
Uncharacterized protein C1F7.10

1

0

High-throughput

0.460

High

314014

MOC3
Transcriptional regulatory protein moc3

1

0

High-throughput

0.460

High

151911

EDC4L
Enhancer of mRNA-decapping protein 4-like protein pdc1

1

0

Small-scale

0.458

High

206935

OGA1
Ribosome-associated protein oga1

1

0

Small-scale

0.458

High

207126

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

0

Small-scale

0.458

High

237548

RRS1
Ribosome biogenesis regulatory protein homolog

1

0

Small-scale

0.458

High

267632

RPN8
26S proteasome regulatory subunit rpn8

1

0

Small-scale

0.458

High

267744

FKS4
1,3-beta-glucan synthase component bgs4

1

0

Small-scale

0.458

High

267777

NUP60
Nucleoporin nup60

1

0

Small-scale

0.458

High

313922

APQ12
Nuclear membrane organization protein apq12

1

0

Small-scale

0.458

High

313958

ATG16
Autophagy protein 16

1

0

Small-scale

0.458

High

313963

RL19A
Large ribosomal subunit protein eL19A

1

0

Small-scale

0.458

High

313975

RL5A
Large ribosomal subunit protein uL18A

1

0

Small-scale

0.458

High

313980

RL22
Large ribosomal subunit protein eL22

1

0

Small-scale

0.458

High

313985

KRI1
Protein kri1

1

0

Small-scale

0.458

High

313988

EFG1P
rRNA-processing protein efg1

1

0

Small-scale

0.458

High

313989

CIP2
RNA-binding post-transcriptional regulator cip2

1

0

Small-scale

0.458

High

313999

RPN7
26S proteasome regulatory subunit rpn7

1

0

Small-scale

0.458

High

314007

YJU3
Uncharacterized protein P25A2.03

1

0

Small-scale

0.458

High

314013

CLC1
Clathrin light chain

1

0

Small-scale

0.458

High

314017

RED1
NURS complex subunit red1

1

0

High-throughput

0.458

High

314018

DYLT
Dynein light chain Tctex-type

1

0

Small-scale

0.458

High

314020

RL21A
Large ribosomal subunit protein eL21A

1

0

Small-scale

0.458

High

314021

YGL1
Uncharacterized protein C216.01c

1

0

Small-scale

0.458

High

153742

YET4
Meiotically up-regulated protein C8C9.04

1

6

Small-scale

0.437

High

237808

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

2

Small-scale

0.437

High

313960

ODO2
Probable dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

2

Small-scale

0.437

High

152940

PIL2
Probable sphingolipid long chain base-responsive protein pil2

1

0

High-throughput

0.251

Low

267438

YOG8
Putative uncharacterized protein C15D4.08c

1

0

High-throughput

0.251

Low

313987

YAE3
TBC domain-containing protein C23D3.03c

1

0

High-throughput

0.251

Low

151142

PUN1
SUR7 family protein pun1

1

0

Small-scale

0.249

Low

313624

HMT2
Sulfide:quinone oxidoreductase, mitochondrial

1

0

Small-scale

0.249

Low

313969

ATPB
ATP synthase subunit beta, mitochondrial

1

0

Small-scale

0.249

Low

313973

BFR1
Brefeldin A resistance protein

1

0

Small-scale

0.249

Low

313976

BUT2
Uba3-binding protein but2

1

0

Small-scale

0.249

Low

313978

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

Small-scale

0.249

Low

313996

PDI1
Putative protein disulfide-isomerase C1F5.02

1

0

Small-scale

0.249

Low

314000

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

0

Small-scale

0.249

Low

314001

YKP6
Uncharacterized protein C589.06c

1

0

Small-scale

0.249

Low

314003

PTR2
Probable peptide transporter ptr2

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025