Protein: RPGF5
Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (M-Ras-regulated Rap GEF) (MR-GEF) (Related to Epac) (Repac)

Gene: RPGF5, RAPGEF5
Organism: Homo sapiens
Interactions: 34
UniProt ID: Q92565

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005886 - plasma membrane
GO:0007264 - small GTPase-mediated signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

919657

RAP1A
Ras-related protein Rap-1A

2

20

Small-scale

0.778

High

679277

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

2

0

High-throughput

0.770

High

156101

RASM
Ras-related protein M-Ras

1

20

Small-scale

0.724

High

486045

RAP2A
Ras-related protein Rap-2a

1

20

Small-scale

0.647

High

475121

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

5

High-throughput

0.628

High

556718

ANK1
Ankyrin-1

2

3

High-throughput

0.628

High

610752

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

2

7

High-throughput

0.628

High

787385

PK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

2

2

High-throughput

0.628

High

965136

ANK2
Ankyrin-2

2

3

High-throughput

0.628

High

1021441

ANK3
Ankyrin-3

2

3

High-throughput

0.628

High

1058699

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

2

4

High-throughput

0.628

High

1068616

PLEC
Plectin

2

2

High-throughput

0.628

High

1078041

HERC1
Probable E3 ubiquitin-protein ligase HERC1

2

4

High-throughput

0.628

High

1113815

GRDN
Girdin

2

1

High-throughput

0.628

High

1267358

WNK1
Serine/threonine-protein kinase WNK1

2

6

High-throughput

0.628

High

1202998

LIPB1
Liprin-beta-1

2

0

High-throughput

0.602

High

297242

DDHD2
Phospholipase DDHD2

2

2

High-throughput

0.574

High

1032935

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

2

3

High-throughput

0.574

High

1267359

TBB1
Tubulin beta-1 chain

2

1

High-throughput

0.574

High

1123536

HS904
Putative heat shock protein HSP 90-alpha A4

2

1

High-throughput

0.552

High

1038293

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

5

High-throughput

0.536

High

1052913

FLNC
Filamin-C

1

3

High-throughput

0.536

High

1250788

VANG1
Vang-like protein 1

1

0

High-throughput

0.518

High

966856

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

0

High-throughput

0.513

High

557756

NCK1
SH2/SH3 adapter protein NCK1

1

20

Small-scale

0.479

High

581033

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

5

Small-scale

0.479

High

787278

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

2

Small-scale

0.479

High

531923

PDIA4
Protein disulfide-isomerase A4

1

2

High-throughput

0.470

High

1267361

KCND3
Potassium voltage-gated channel subfamily D member 3

1

0

Small-scale

0.458

High

1163766

RICTR
Rapamycin-insensitive companion of mTOR

2

0

High-throughput

0.328

High

1267360

ZNHI2
Zinc finger HIT domain-containing protein 2

2

0

High-throughput

0.328

High

473584

TM253
Transmembrane protein 253

1

0

High-throughput

0.282

High

1127754

PLAC9
Placenta-specific protein 9

1

0

High-throughput

0.282

High

1146136

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024