Protein: AL4A1
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (P5C dehydrogenase) (EC 1.2.1.88) (Aldehyde dehydrogenase family 4 member A1) (L-glutamate gamma-semialdehyde dehydrogenase)

Gene: AL4A1, ALDH4A1
Organism: Homo sapiens
Interactions: 54
UniProt ID: P30038

Gene Ontology (top 5):
GO:0003842 - 1-pyrroline-5-carboxylate dehydrogenase activity
GO:0004029 - aldehyde dehydrogenase (NAD+) activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

670528

AL4A1
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

2

14

Small-scale

0.777

High

670546

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

3

3

Small-scale

0.640

High

670535

ARRB1
Beta-arrestin-1

2

0

High-throughput

0.602

High

274182

STK16
Serine/threonine-protein kinase 16

1

1

High-throughput

0.536

High

496381

TAU
Microtubule-associated protein tau

1

6

High-throughput

0.536

High

646371

KAD4
Adenylate kinase 4, mitochondrial

1

3

High-throughput

0.536

High

670540

RBBP4
Histone-binding protein RBBP4

1

8

High-throughput

0.515

High

670530

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

1

0

High-throughput

0.513

High

670548

ACSM5
Acyl-coenzyme A synthetase ACSM5, mitochondrial

1

0

High-throughput

0.513

High

670549

FAHD1
Oxaloacetate decarboxylase, mitochondrial

1

0

High-throughput

0.513

High

670554

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

1

0

High-throughput

0.513

High

670559

GATA
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial

1

0

High-throughput

0.513

High

670565

MRM2
rRNA methyltransferase 2, mitochondrial

1

0

High-throughput

0.513

High

670566

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

174645

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

4

High-throughput

0.501

High

394179

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

156796

FFAR1
Free fatty acid receptor 1

1

1

High-throughput

0.489

High

303654

OR2A4
Olfactory receptor 2A4

1

4

High-throughput

0.489

High

670544

RB33A
Ras-related protein Rab-33A

1

5

High-throughput

0.489

High

670552

OIT3
Oncoprotein-induced transcript 3 protein

1

1

High-throughput

0.489

High

226610

PRKN
E3 ubiquitin-protein ligase parkin

1

10

High-throughput

0.479

High

262720

CISY
Citrate synthase, mitochondrial

1

2

High-throughput

0.479

High

264846

MPPB
Mitochondrial-processing peptidase subunit beta

1

4

High-throughput

0.479

High

327365

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

1

High-throughput

0.479

High

670532

MDHM
Malate dehydrogenase, mitochondrial

1

3

High-throughput

0.479

High

670533

EFTS
Elongation factor Ts, mitochondrial

1

1

High-throughput

0.479

High

670536

EFTU
Elongation factor Tu, mitochondrial

1

5

High-throughput

0.479

High

670538

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

1

High-throughput

0.479

High

670539

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

3

High-throughput

0.479

High

670541

MPPA
Mitochondrial-processing peptidase subunit alpha

1

4

High-throughput

0.479

High

670543

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

1

High-throughput

0.479

High

670545

PDK1
[Pyruvate dehydrogenase

1

2

High-throughput

0.479

High

670547

MRM1
rRNA methyltransferase 1, mitochondrial

1

2

High-throughput

0.479

High

670553

FAKD4
FAST kinase domain-containing protein 4

1

1

High-throughput

0.479

High

670557

TR61B
tRNA

1

1

High-throughput

0.479

High

670558

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

2

High-throughput

0.479

High

670560

MET17
Ribosome assembly protein METTL17, mitochondrial

1

1

High-throughput

0.479

High

670561

MRES1
Mitochondrial transcription rescue factor 1

1

1

High-throughput

0.479

High

670562

HDAC6
Histone deacetylase 6

1

1

High-throughput

0.479

High

670563

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

1

High-throughput

0.479

High

670564

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

396199

ARGI1
Arginase-1

1

0

High-throughput

0.460

High

670556

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.458

High

670531

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

670537

WDR5
WD repeat-containing protein 5

1

3

High-throughput

0.437

High

670542

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.437

High

670551

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

670550

T184A
Transmembrane protein 184A

2

0

High-throughput

0.328

High

670529

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.279

Low

670555

LRC46
Leucine-rich repeat-containing protein 46

1

0

High-throughput

0.279

Low

670567

GPR45
Probable G-protein coupled receptor 45

1

0

High-throughput

0.279

Low

650444

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

670534

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024