Protein: ABCA1
Phospholipid-transporting ATPase ABCA1 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 1) (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1) (Cholesterol efflux regulatory protein)

Gene: ABCA1
Organism: Homo sapiens
Interactions: 47
UniProt ID: O95477

Gene Ontology (top 5):
GO:0002790 - peptide secretion
GO:0005102 - signaling receptor binding
GO:0005524 - ATP binding
GO:0005548 - phospholipid transporter activity
GO:0005768 - endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

315232

APOA1
Apolipoprotein A-I

4

2

Small-scale

0.692

High

315257

ABCAC
Glucosylceramide transporter ABCA12

1

5

Small-scale

0.665

High

315243

NR1H2
Oxysterols receptor LXR-beta

3

3

Small-scale

0.633

High

315251

SNTB2
Beta-2-syntrophin

2

6

Small-scale

0.626

High

174029

SPTC1
Serine palmitoyltransferase 1

2

1

Small-scale

0.594

High

315241

UTRN
Utrophin

2

2

Small-scale

0.584

High

315239

CALX
Calnexin

1

2

Small-scale

0.536

High

315250

SNTA1
Alpha-1-syntrophin

1

8

Small-scale

0.536

High

315245

CDC42
Cell division control protein 42 homolog

1

1

Small-scale

0.534

High

315252

SNTB1
Beta-1-syntrophin

1

4

Small-scale

0.506

High

315263

ERBIN
Erbin

1

0

Small-scale

0.505

High

315249

FADD
FAS-associated death domain protein

1

0

Small-scale

0.504

High

315233

DMD
Dystrophin

1

2

Small-scale

0.500

High

279382

FLOT1
Flotillin-1

1

0

Small-scale

0.493

High

315258

STX12
Syntaxin-12

1

0

Small-scale

0.493

High

315256

PRP8
Pre-mRNA-processing-splicing factor 8

1

1

Small-scale

0.481

High

315235

CSK22
Casein kinase II subunit alpha'

1

0

Small-scale

0.480

High

315236

FLNA
Filamin-A

1

0

Small-scale

0.479

High

315242

KIF11
Kinesin-like protein KIF11

1

0

Small-scale

0.479

High

167056

ARHGB
Rho guanine nucleotide exchange factor 11

1

2

Small-scale

0.479

High

226151

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

280010

MPDZ
Multiple PDZ domain protein

1

3

Small-scale

0.479

High

315230

EGFR
Epidermal growth factor receptor

1

4

High-throughput

0.479

High

315231

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.479

High

315247

TF65
Transcription factor p65

1

1

Small-scale

0.479

High

315254

DLG2
Disks large homolog 2

1

1

Small-scale

0.479

High

315260

DLG3
Disks large homolog 3

1

1

Small-scale

0.479

High

315261

CSN5
COP9 signalosome complex subunit 5

1

1

Small-scale

0.479

High

315264

LIN7B
Protein lin-7 homolog B

1

7

Small-scale

0.479

High

315266

ARHGC
Rho guanine nucleotide exchange factor 12

1

1

Small-scale

0.479

High

315237

SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

1

0

Small-scale

0.460

High

315238

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

0

High-throughput

0.460

High

315267

ATX10
Ataxin-10

1

0

Small-scale

0.460

High

159822

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

0

Small-scale

0.458

High

315259

LNX1
E3 ubiquitin-protein ligase LNX

1

3

Small-scale

0.457

High

315265

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.457

High

239673

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.445

High

246416

DTNB
Dystrobrevin beta

1

2

Small-scale

0.445

High

315244

CD81
CD81 antigen

1

1

High-throughput

0.445

High

315253

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

1

High-throughput

0.445

High

315246

CSN2
COP9 signalosome complex subunit 2

2

0

Small-scale

0.305

High

315268

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.282

High

315262

IMP1L
Mitochondrial inner membrane protease subunit 1

1

0

High-throughput

0.279

Low

315248

AOXA
Aldehyde oxidase

1

0

Small-scale

0.251

Low

315255

UGPA
UTP--glucose-1-phosphate uridylyltransferase

1

0

Small-scale

0.251

Low

315234

EGR1
Early growth response protein 1

1

0

High-throughput

0.249

Low

315240

FUS
RNA-binding protein FUS

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024