Protein: NLK
Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)

Gene: NLK
Organism: Homo sapiens
Interactions: 70
UniProt ID: Q9UBE8

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004707 - MAP kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1353975

NLK
Serine/threonine-protein kinase NLK

6

18

Small-scale

0.940

High

1353980

SHAN2
SH3 and multiple ankyrin repeat domains protein 2

2

13

High-throughput

0.811

High

201451

M3K7
Mitogen-activated protein kinase kinase kinase 7

2

15

Small-scale

0.759

High

804358

NOTC1
Neurogenic locus notch homolog protein 1

1

1

Small-scale

0.724

High

1353978

LEF1
Lymphoid enhancer-binding factor 1

5

8

Small-scale

0.710

High

1331087

ZHX3
Zinc fingers and homeoboxes protein 3

4

1

High-throughput

0.703

High

801795

RAGP1
Ran GTPase-activating protein 1

1

5

High-throughput

0.691

High

864849

MK12
Mitogen-activated protein kinase 12

1

18

High-throughput

0.691

High

1300880

PASK
PAS domain-containing serine/threonine-protein kinase

1

13

High-throughput

0.691

High

660738

GRN
Progranulin

3

4

High-throughput

0.683

High

1329779

HIPK2
Homeodomain-interacting protein kinase 2

1

18

Small-scale

0.680

High

486839

MYB
Transcriptional activator Myb

2

20

Small-scale

0.657

High

1035615

SMAD4
Mothers against decapentaplegic homolog 4

2

7

High-throughput

0.647

High

1230058

RPTOR
Regulatory-associated protein of mTOR

1

8

Small-scale

0.647

High

1259744

F222B
Protein FAM222B

2

1

High-throughput

0.628

High

1349339

CNOT2
CCR4-NOT transcription complex subunit 2

2

1

High-throughput

0.628

High

1353977

TRPS1
Zinc finger transcription factor Trps1

2

7

High-throughput

0.628

High

868783

ATX1
Ataxin-1

2

2

High-throughput

0.620

High

200143

DAPK3
Death-associated protein kinase 3

1

20

Small-scale

0.618

High

1137444

F222A
Protein FAM222A

3

5

High-throughput

0.616

High

792043

HD
Huntingtin

2

3

Small-scale

0.601

High

1270812

CBP
CREB-binding protein

2

8

Small-scale

0.595

High

1353976

NDOR1
NADPH-dependent diflavin oxidoreductase 1

2

0

High-throughput

0.580

High

486863

MYBA
Myb-related protein A

1

20

Small-scale

0.578

High

1332425

WDCP
WD repeat and coiled-coil-containing protein

2

1

High-throughput

0.574

High

642174

KRA59
Keratin-associated protein 5-9

1

3

High-throughput

0.573

High

1102964

QRIC1
Transcriptional regulator QRICH1

1

4

High-throughput

0.573

High

1317342

KRA42
Keratin-associated protein 4-2

1

2

High-throughput

0.573

High

387653

P53
Cellular tumor antigen p53

1

8

Small-scale

0.561

High

958172

FOXO4
Forkhead box protein O4

1

5

Small-scale

0.561

High

1024433

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

3

Small-scale

0.561

High

1318370

FOXP3
Forkhead box protein P3

1

4

Small-scale

0.561

High

1348522

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

1

3

Small-scale

0.561

High

1299482

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.558

High

1154216

KRA56
Keratin-associated protein 5-6

1

0

High-throughput

0.549

High

1232740

RDHE2
Epidermal retinol dehydrogenase 2

1

1

High-throughput

0.541

High

157252

BACH1
Transcription regulator protein BACH1

1

4

High-throughput

0.536

High

200693

CP110
Centriolar coiled-coil protein of 110 kDa

1

1

High-throughput

0.536

High

257421

CNOT3
CCR4-NOT transcription complex subunit 3

1

4

High-throughput

0.536

High

538050

KPYM
Pyruvate kinase PKM

1

6

High-throughput

0.536

High

834859

RBP2
E3 SUMO-protein ligase RanBP2

1

3

High-throughput

0.536

High

980897

TLE3
Transducin-like enhancer protein 3

1

5

High-throughput

0.536

High

1049911

UBP2L
Ubiquitin-associated protein 2-like

1

5

High-throughput

0.536

High

1060952

IMB1
Importin subunit beta-1

1

5

High-throughput

0.536

High

1218193

CEP97
Centrosomal protein of 97 kDa

1

1

High-throughput

0.536

High

1318955

TB182
182 kDa tankyrase-1-binding protein

1

7

High-throughput

0.536

High

521312

SKI
Ski oncogene

1

0

High-throughput

0.513

High

1312789

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

1

0

High-throughput

0.513

High

1353979

CNO11
CCR4-NOT transcription complex subunit 11

1

0

High-throughput

0.513

High

776844

STAT3
Signal transducer and activator of transcription 3

1

6

Small-scale

0.484

High

888786

KR101
Keratin-associated protein 10-1

1

2

High-throughput

0.481

High

889020

KR103
Keratin-associated protein 10-3

1

2

High-throughput

0.481

High

206860

FOXO3
Forkhead box protein O3

1

9

Small-scale

0.479

High

486975

MYBB
Myb-related protein B

1

20

Small-scale

0.479

High

717393

CTNB1
Catenin beta-1

1

9

Small-scale

0.479

High

727965

SOX11
Transcription factor SOX-11

1

5

Small-scale

0.479

High

808983

YAP1
Transcriptional coactivator YAP1

1

3

Small-scale

0.479

High

885061

FBXW4
F-box/WD repeat-containing protein 4

1

8

Small-scale

0.479

High

941539

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.479

High

1016259

FOXO1
Forkhead box protein O1

1

8

Small-scale

0.479

High

1031292

SKP2
S-phase kinase-associated protein 2

1

3

Small-scale

0.479

High

1041240

CUL1
Cullin-1

1

5

Small-scale

0.479

High

1050545

TFDP1
Transcription factor Dp-1

1

6

Small-scale

0.479

High

1123680

DCAF6
DDB1- and CUL4-associated factor 6

1

8

High-throughput

0.479

High

1343256

TF7L2
Transcription factor 7-like 2

1

7

Small-scale

0.479

High

963008

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.458

High

1282438

FBXW5
F-box/WD repeat-containing protein 5

1

0

Small-scale

0.458

High

1139884

OBI1
ORC ubiquitin ligase 1

1

0

High-throughput

0.279

Low

426804

ASGR1
Asialoglycoprotein receptor 1

1

0

High-throughput

0.265

Low


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Last updated: 15 Jul 2024