Protein: VPS11
Vacuolar protein sorting-associated protein 11 homolog (hVPS11) (RING finger protein 108)

Gene: VPS11
Organism: Homo sapiens
Interactions: 86
UniProt ID: Q9H270

Gene Ontology (top 5):
GO:0000166 - nucleotide binding
GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
GO:0005768 - endosome
GO:0005769 - early endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1260134

TGFA1
Transforming growth factor-beta receptor-associated protein 1

7

16

Small-scale

0.966

High

833167

VPS41
Vacuolar protein sorting-associated protein 41 homolog

7

17

Small-scale

0.962

High

1329147

VPS18
Vacuolar protein sorting-associated protein 18 homolog

10

20

Small-scale

0.755

High

1295093

VPS39
Vam6/Vps39-like protein

9

16

Small-scale

0.754

High

1329123

VPS16
Vacuolar protein sorting-associated protein 16 homolog

6

13

Small-scale

0.736

High

1284635

VP33A
Vacuolar protein sorting-associated protein 33A

6

17

Small-scale

0.733

High

1232471

VPS8
Vacuolar protein sorting-associated protein 8 homolog

4

7

Small-scale

0.694

High

919861

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

3

High-throughput

0.647

High

932576

UB2L3
Ubiquitin-conjugating enzyme E2 L3

1

4

High-throughput

0.647

High

1329144

GGA3
ADP-ribosylation factor-binding protein GGA3

1

3

Small-scale

0.647

High

845237

RAB7A
Ras-related protein Rab-7a

3

17

Small-scale

0.646

High

161873

ZN263
Zinc finger protein 263

2

1

High-throughput

0.628

High

1138922

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

5

High-throughput

0.625

High

889682

KR108
Keratin-associated protein 10-8

3

2

High-throughput

0.616

High

718188

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.613

High

1329152

PKHM1
Pleckstrin homology domain-containing family M member 1

2

3

Small-scale

0.611

High

896375

UBE2K
Ubiquitin-conjugating enzyme E2 K

1

4

High-throughput

0.594

High

1283420

RN166
E3 ubiquitin-protein ligase RNF166

1

0

High-throughput

0.586

High

1101835

TM266
Transmembrane protein 266

2

1

High-throughput

0.574

High

1283768

ISOC2
Isochorismatase domain-containing protein 2

2

1

High-throughput

0.574

High

547212

EZRI
Ezrin

1

2

Small-scale

0.573

High

1165216

LRSM1
E3 ubiquitin-protein ligase LRSAM1

1

1

High-throughput

0.541

High

804340

NOTC1
Neurogenic locus notch homolog protein 1

1

1

High-throughput

0.536

High

1216103

TCAM1
TIR domain-containing adapter molecule 1

1

1

High-throughput

0.536

High

1285071

ARRD3
Arrestin domain-containing protein 3

1

2

High-throughput

0.536

High

1329149

RBX2
RING-box protein 2

1

1

High-throughput

0.536

High

178771

STX7
Syntaxin-7

1

14

Small-scale

0.534

High

1298568

RILP
Rab-interacting lysosomal protein

1

3

Small-scale

0.527

High

1023337

TRI32
E3 ubiquitin-protein ligase TRIM32

1

0

High-throughput

0.518

High

1306579

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.518

High

1329145

RN181
E3 ubiquitin-protein ligase RNF181

1

0

High-throughput

0.518

High

882806

STX17
Syntaxin-17

1

4

Small-scale

0.515

High

395741

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.515

High

640150

MOES
Moesin

1

2

Small-scale

0.501

High

719772

RADI
Radixin

1

2

Small-scale

0.501

High

1083988

STX1A
Syntaxin-1A

1

13

Small-scale

0.501

High

647956

MARK3
MAP/microtubule affinity-regulating kinase 3

1

1

High-throughput

0.494

High

882557

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

1

High-throughput

0.494

High

158031

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.493

High

443798

VIME
Vimentin

1

0

High-throughput

0.493

High

263958

HYPM
Huntingtin-interacting protein M

1

1

High-throughput

0.489

High

345138

CYTA
Cystatin-A

1

1

High-throughput

0.489

High

642990

S10A4
Protein S100-A4

1

2

High-throughput

0.489

High

1050056

SCRIB
Protein scribble homolog

1

1

High-throughput

0.489

High

1093438

SAMTR
S-adenosylmethionine sensor upstream of mTORC1

1

1

High-throughput

0.489

High

1184549

BOP
Protein Bop

1

1

High-throughput

0.489

High

1224281

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

2

High-throughput

0.489

High

1234864

TTC9C
Tetratricopeptide repeat protein 9C

1

1

High-throughput

0.489

High

1270227

THRSP
Thyroid hormone-inducible hepatic protein

1

3

High-throughput

0.489

High

1313634

LRC61
Leucine-rich repeat-containing protein 61

1

1

High-throughput

0.489

High

1329142

M1IP1
Mid1-interacting protein 1

1

3

High-throughput

0.489

High

1329151

CC018
Uncharacterized protein C3orf18

1

3

High-throughput

0.489

High

385501

NTRK1
High affinity nerve growth factor receptor

1

4

High-throughput

0.479

High

592486

RAB5A
Ras-related protein Rab-5A

1

15

High-throughput

0.479

High

845725

RAB9A
Ras-related protein Rab-9A

1

15

High-throughput

0.479

High

914349

RB11A
Ras-related protein Rab-11A

1

4

Small-scale

0.479

High

1284388

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

3

High-throughput

0.479

High

1329148

UVRAG
UV radiation resistance-associated gene protein

1

3

Small-scale

0.479

High

1329150

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

258189

DNJB6
DnaJ homolog subfamily B member 6

1

1

High-throughput

0.470

High

349637

RASH
GTPase HRas

1

3

High-throughput

0.470

High

557497

PECA1
Platelet endothelial cell adhesion molecule

1

1

High-throughput

0.470

High

609530

FGFR3
Fibroblast growth factor receptor 3

1

4

High-throughput

0.470

High

167715

LSM1
U6 snRNA-associated Sm-like protein LSm1

1

4

High-throughput

0.464

High

1183830

MON1B
Vacuolar fusion protein MON1 homolog B

1

8

Small-scale

0.464

High

1139435

ECM29
Proteasome adapter and scaffold protein ECM29

1

0

Small-scale

0.460

High

888992

KR103
Keratin-associated protein 10-3

1

2

High-throughput

0.439

High

1018047

GRSF1
G-rich sequence factor 1

1

1

Small-scale

0.439

High

1171670

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

1269588

ESR2
Estrogen receptor beta

1

3

High-throughput

0.437

High

882048

BACE1
Beta-secretase 1

1

0

Small-scale

0.426

High

626725

EDNRA
Endothelin-1 receptor

1

3

Small-scale

0.407

High

1329143

PARVA
Alpha-parvin

3

0

High-throughput

0.347

High

518945

RLBP1
Retinaldehyde-binding protein 1

1

0

High-throughput

0.279

Low

942250

GTF2I
General transcription factor II-I

1

0

High-throughput

0.279

Low

986847

PSME1
Proteasome activator complex subunit 1

1

0

High-throughput

0.279

Low

1121459

CCD92
Coiled-coil domain-containing protein 92

1

0

High-throughput

0.279

Low

1174564

CYS1
Cystin-1

1

0

High-throughput

0.279

Low

1329141

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.279

Low

1329146

CAMP3
Calmodulin-regulated spectrin-associated protein 3

1

0

High-throughput

0.279

Low

414059

GELS
Gelsolin

1

0

High-throughput

0.268

Low

657980

CLAT
Choline O-acetyltransferase

1

0

High-throughput

0.268

Low

1191568

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.268

Low

1329153

Q9Y649
GW128

1

0

High-throughput

0.268

Low

232499

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.265

Low

1265992

AP2B
Transcription factor AP-2-beta

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024