Protein: PAK3
Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase 3) (PAK-3)

Gene: PAK3
Organism: Homo sapiens
Interactions: 33
UniProt ID: O75914

Gene Ontology (top 5):
GO:0002223 - stimulatory C-type lectin receptor signaling pathway
GO:0004674 - protein serine/threonine kinase activity
GO:0004708 - MAP kinase kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

277599

CDC42
Cell division control protein 42 homolog

4

20

Small-scale

0.900

High

277602

RAC1
Ras-related C3 botulinum toxin substrate 1

3

20

Small-scale

0.843

High

277605

ARHG7
Rho guanine nucleotide exchange factor 7

2

19

Small-scale

0.793

High

277619

RHOJ
Rho-related GTP-binding protein RhoJ

2

20

High-throughput

0.783

High

277604

PAK1
Serine/threonine-protein kinase PAK 1

1

17

High-throughput

0.691

High

277593

PAK3
Serine/threonine-protein kinase PAK 3

1

16

Small-scale

0.647

High

277598

PLK1
Serine/threonine-protein kinase PLK1

1

16

Small-scale

0.618

High

277607

MK14
Mitogen-activated protein kinase 14

1

13

Small-scale

0.618

High

277609

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

277615

PALLD
Palladin

1

5

High-throughput

0.618

High

277620

GIT1
ARF GTPase-activating protein GIT1

1

13

Small-scale

0.618

High

277603

STK4
Serine/threonine-protein kinase 4

1

18

High-throughput

0.575

High

277613

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

2

2

High-throughput

0.574

High

158078

TX1B3
Tax1-binding protein 3

1

13

High-throughput

0.536

High

277596

ITB8
Integrin beta-8

1

8

High-throughput

0.536

High

277608

EFMT2
EEF1A lysine methyltransferase 2

1

1

High-throughput

0.536

High

277616

PTPR2
Receptor-type tyrosine-protein phosphatase N2

1

6

High-throughput

0.536

High

277617

RM38
Large ribosomal subunit protein mL38

1

3

High-throughput

0.536

High

277611

COMD2
COMM domain-containing protein 2

1

0

High-throughput

0.513

High

277621

MSRB2
Methionine-R-sulfoxide reductase B2, mitochondrial

1

0

High-throughput

0.513

High

277597

SYUA
Alpha-synuclein

1

4

Small-scale

0.501

High

241401

H2B1K
Histone H2B type 1-K

1

17

High-throughput

0.479

High

277594

TAU
Microtubule-associated protein tau

1

6

High-throughput

0.479

High

277595

NCK1
SH2/SH3 adapter protein NCK1

1

20

Small-scale

0.479

High

277600

ABCE1
ATP-binding cassette sub-family E member 1

1

2

High-throughput

0.479

High

277601

H2B1C
Histone H2B type 1-C/E/F/G/I

1

17

High-throughput

0.479

High

277606

ITSN1
Intersectin-1

1

16

Small-scale

0.479

High

277610

RM52
Large ribosomal subunit protein mL52

1

0

High-throughput

0.279

Low

277612

RASF8
Ras association domain-containing protein 8

1

0

High-throughput

0.279

Low

277618

RAMAC
RNA guanine-N7 methyltransferase activating subunit

1

0

High-throughput

0.279

Low

277622

RT18C
Small ribosomal subunit protein bS18m

1

0

High-throughput

0.279

Low

277614

POF1B
Protein POF1B

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024