Protein: CYH2
Cytohesin-2 (ARF exchange factor) (ARF nucleotide-binding site opener) (Protein ARNO) (PH, SEC7 and coiled-coil domain-containing protein 2)

Gene: CYH2, CYTH2
Organism: Homo sapiens
Interactions: 44
UniProt ID: Q99418

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1262771

ICEF1
Interactor protein for cytohesin exchange factors 1

5

20

Small-scale

0.936

High

1281529

CNKR1
Connector enhancer of kinase suppressor of ras 1

4

18

High-throughput

0.902

High

950545

ARF1
ADP-ribosylation factor 1

4

14

Small-scale

0.885

High

913064

ARF6
ADP-ribosylation factor 6

3

15

Small-scale

0.840

High

1293344

CC120
Coiled-coil domain-containing protein 120

7

11

High-throughput

0.754

High

830780

ARL4D
ADP-ribosylation factor-like protein 4D

1

20

Small-scale

0.740

High

1108765

INAVA
Innate immunity activator protein

5

11

Small-scale

0.719

High

1074113

CYH1
Cytohesin-1

1

9

High-throughput

0.691

High

1050490

DOCK1
Dedicator of cytokinesis protein 1

1

0

Small-scale

0.687

High

240484

CYTIP
Cytohesin-interacting protein

3

17

High-throughput

0.667

High

734743

TRI23
E3 ubiquitin-protein ligase TRIM23

1

20

Small-scale

0.647

High

411481

INSR
Insulin receptor

1

4

Small-scale

0.646

High

724563

IRS1
Insulin receptor substrate 1

1

4

Small-scale

0.646

High

1116813

CCD40
Coiled-coil domain-containing protein 40

2

3

High-throughput

0.628

High

1085479

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.622

High

776229

ARL4A
ADP-ribosylation factor-like protein 4A

1

20

Small-scale

0.621

High

924812

GRB2
Growth factor receptor-bound protein 2

1

4

High-throughput

0.618

High

548328

FOSL2
Fos-related antigen 2

3

6

High-throughput

0.609

High

982417

1433F
14-3-3 protein eta

2

20

High-throughput

0.601

High

1303455

VPP2
V-type proton ATPase 116 kDa subunit a 2

2

4

Small-scale

0.595

High

664346

AA2AR
Adenosine receptor A2a

1

1

Small-scale

0.586

High

686041

ARRB2
Beta-arrestin-2

1

3

Small-scale

0.561

High

827264

ARRB1
Beta-arrestin-1

1

3

Small-scale

0.561

High

837645

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

4

Small-scale

0.561

High

1283813

PLPL2
Patatin-like phospholipase domain-containing protein 2

1

2

Small-scale

0.552

High

626236

APC
Adenomatous polyposis coli protein

1

1

High-throughput

0.541

High

158111

TX1B3
Tax1-binding protein 3

1

9

High-throughput

0.536

High

997448

VAC14
Protein VAC14 homolog

1

3

High-throughput

0.536

High

1121428

P5CR3
Pyrroline-5-carboxylate reductase 3

1

1

High-throughput

0.536

High

1303456

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

1

High-throughput

0.536

High

684286

1433S
14-3-3 protein sigma

1

20

High-throughput

0.515

High

1303453

STRP2
Striatin-interacting protein 2

1

0

High-throughput

0.513

High

1303449

MYD88
Myeloid differentiation primary response protein MyD88

1

0

Small-scale

0.512

High

1035683

VPP3
V-type proton ATPase 116 kDa subunit a 3

1

4

Small-scale

0.501

High

1274133

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

4

Small-scale

0.501

High

1303450

VPP4
V-type proton ATPase 116 kDa subunit a 4

1

4

Small-scale

0.501

High

225029

ZNRD2
Protein ZNRD2

1

1

High-throughput

0.489

High

787297

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

3

Small-scale

0.481

High

375996

ALDOA
Fructose-bisphosphate aldolase A

1

0

Small-scale

0.480

High

1303454

MTMR7
Myotubularin-related protein 7

1

1

High-throughput

0.479

High

1303451

GGA3
ADP-ribosylation factor-binding protein GGA3

1

1

Small-scale

0.457

High

396646

ITB2
Integrin beta-2

1

1

Small-scale

0.457

High

1299724

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

6

High-throughput

0.445

High

1303452

ATIF1
ATPase inhibitor, mitochondrial

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024