Protein: RTKN
Rhotekin

Gene: RTKN
Organism: Homo sapiens
Interactions: 108
UniProt ID: Q9BST9

Gene Ontology (top 5):
GO:0000281 - mitotic cytokinesis
GO:0000915 - actomyosin contractile ring assembly
GO:0005095 - GTPase inhibitor activity
GO:0005525 - GTP binding
GO:0005826 - actomyosin contractile ring

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

900848

RHOA
Transforming protein RhoA

17

7

Small-scale

0.984

High

436482

RHOC
Rho-related GTP-binding protein RhoC

2

7

High-throughput

0.811

High

915929

RHOB
Rho-related GTP-binding protein RhoB

2

7

Small-scale

0.768

High

235578

VINEX
Vinexin

1

3

Small-scale

0.700

High

1263862

ACO11
Acyl-coenzyme A thioesterase 11

1

0

High-throughput

0.656

High

1016933

AKP13
A-kinase anchor protein 13

1

1

Small-scale

0.647

High

683676

1433B
14-3-3 protein beta/alpha

2

5

High-throughput

0.628

High

231703

KIF1B
Kinesin-like protein KIF1B

1

2

High-throughput

0.618

High

925570

RAC1
Ras-related C3 botulinum toxin substrate 1

1

5

Small-scale

0.618

High

1022443

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

2

High-throughput

0.618

High

1136542

SPD2A
SH3 and PX domain-containing protein 2A

1

2

High-throughput

0.618

High

1153357

PKHA7
Pleckstrin homology domain-containing family A member 7

1

2

High-throughput

0.618

High

1311598

PKHA5
Pleckstrin homology domain-containing family A member 5

1

4

High-throughput

0.618

High

1311600

KI13B
Kinesin-like protein KIF13B

1

2

High-throughput

0.618

High

1311612

GAB2
GRB2-associated-binding protein 2

1

3

High-throughput

0.618

High

1311614

STA13
StAR-related lipid transfer protein 13

1

1

High-throughput

0.618

High

253405

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

0

High-throughput

0.586

High

960408

CDK16
Cyclin-dependent kinase 16

1

0

High-throughput

0.586

High

997212

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

0

High-throughput

0.586

High

1057196

MELK
Maternal embryonic leucine zipper kinase

1

0

High-throughput

0.586

High

1136479

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

0

High-throughput

0.586

High

1197831

PHLB2
Pleckstrin homology-like domain family B member 2

1

0

High-throughput

0.586

High

1217982

KSR1
Kinase suppressor of Ras 1

1

0

High-throughput

0.586

High

1230034

RPTOR
Regulatory-associated protein of mTOR

1

0

High-throughput

0.586

High

1311611

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

0

High-throughput

0.586

High

1311594

DNAI2
Dynein axonemal intermediate chain 2

1

0

High-throughput

0.578

High

982438

1433F
14-3-3 protein eta

1

5

High-throughput

0.554

High

216964

KIF1C
Kinesin-like protein KIF1C

1

2

High-throughput

0.553

High

1256278

SH3R3
E3 ubiquitin-protein ligase SH3RF3

1

3

High-throughput

0.553

High

1311596

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.553

High

158115

TX1B3
Tax1-binding protein 3

1

2

High-throughput

0.536

High

647231

1433T
14-3-3 protein theta

1

5

High-throughput

0.536

High

813717

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.536

High

905059

1433G
14-3-3 protein gamma

1

5

High-throughput

0.536

High

927472

1433Z
14-3-3 protein zeta/delta

1

5

High-throughput

0.536

High

166611

DCLK1
Serine/threonine-protein kinase DCLK1

1

0

High-throughput

0.517

High

230911

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

0

High-throughput

0.517

High

1203941

RGPS2
Ras-specific guanine nucleotide-releasing factor RalGPS2

1

0

High-throughput

0.517

High

1301709

TESK2
Dual specificity testis-specific protein kinase 2

1

0

High-throughput

0.517

High

1311615

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

1

0

High-throughput

0.513

High

277348

ST1C4
Sulfotransferase 1C4

1

0

High-throughput

0.513

High

887603

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

909971

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.513

High

1059455

NAA30
N-alpha-acetyltransferase 30

1

0

High-throughput

0.513

High

1284784

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.513

High

1302613

AEDO
2-aminoethanethiol dioxygenase

1

0

High-throughput

0.513

High

1309191

KLDC3
Kelch domain-containing protein 3

1

0

High-throughput

0.513

High

1311482

FEM1A
Protein fem-1 homolog A

1

0

High-throughput

0.513

High

395614

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

1311595

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

0

Small-scale

0.480

High

264390

GGYF1
GRB10-interacting GYF protein 1

1

1

High-throughput

0.479

High

598519

NF1
Neurofibromin

1

1

High-throughput

0.479

High

673519

MPIP2
M-phase inducer phosphatase 2

1

1

High-throughput

0.479

High

673623

MPIP3
M-phase inducer phosphatase 3

1

1

High-throughput

0.479

High

880814

HDAC4
Histone deacetylase 4

1

1

High-throughput

0.479

High

1020211

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

1

High-throughput

0.479

High

1139631

DEN4C
DENN domain-containing protein 4C

1

2

High-throughput

0.479

High

1167968

GGYF2
GRB10-interacting GYF protein 2

1

1

High-throughput

0.479

High

1173146

SYDE1
Rho GTPase-activating protein SYDE1

1

2

High-throughput

0.479

High

1189728

MYCPP
C-myc promoter-binding protein

1

2

High-throughput

0.479

High

1253337

F110B
Protein FAM110B

1

1

High-throughput

0.479

High

1256251

DEN1A
DENN domain-containing protein 1A

1

2

High-throughput

0.479

High

1260183

HDAC7
Histone deacetylase 7

1

1

High-throughput

0.479

High

1300666

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

1

High-throughput

0.479

High

1309171

F110A
Protein FAM110A

1

1

High-throughput

0.479

High

1311607

NGAP
Ras GTPase-activating protein nGAP

1

1

High-throughput

0.479

High

163208

XPO1
Exportin-1

1

0

High-throughput

0.458

High

237307

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

0

High-throughput

0.458

High

316276

NADK
NAD kinase

1

0

High-throughput

0.458

High

455815

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

1042414

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1162666

LARP1
La-related protein 1

1

0

High-throughput

0.458

High

1185259

RFIP2
Rab11 family-interacting protein 2

1

0

High-throughput

0.458

High

1254247

BICD2
Protein bicaudal D homolog 2

1

0

High-throughput

0.458

High

1269488

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1308715

SIN1
Target of rapamycin complex 2 subunit MAPKAP1

1

0

High-throughput

0.458

High

1311593

OSBL6
Oxysterol-binding protein-related protein 6

1

0

High-throughput

0.458

High

1311597

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1311601

INP5E
Phosphatidylinositol polyphosphate 5-phosphatase type IV

1

0

High-throughput

0.458

High

1311605

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1311606

LIMA1
LIM domain and actin-binding protein 1

1

0

High-throughput

0.458

High

1311608

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

0

High-throughput

0.458

High

1311609

ZBT21
Zinc finger and BTB domain-containing protein 21

1

0

High-throughput

0.458

High

1311613

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.458

High

1076912

PTN14
Tyrosine-protein phosphatase non-receptor type 14

1

1

High-throughput

0.437

High

1149003

AN34A
Ankyrin repeat domain-containing protein 34A

1

1

High-throughput

0.437

High

1260770

DEP1B
DEP domain-containing protein 1B

1

1

High-throughput

0.437

High

245739

B4GT2
Beta-1,4-galactosyltransferase 2

1

0

High-throughput

0.279

Low

319634

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.279

Low

1231718

CLASR
CLK4-associating serine/arginine rich protein

1

0

High-throughput

0.279

Low

1311591

TM147
BOS complex subunit TMEM147

1

0

High-throughput

0.279

Low

1311592

TR61B
tRNA

1

0

High-throughput

0.279

Low

1174933

TLC3B
Ceramide synthase

1

0

High-throughput

0.269

Low

196504

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

0

High-throughput

0.249

Low

553578

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

652104

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

721300

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1060611

ZN638
Zinc finger protein 638

1

0

High-throughput

0.249

Low

1243682

NAV1
Neuron navigator 1

1

0

High-throughput

0.249

Low

1263458

SRS12
Serine/arginine-rich splicing factor 12

1

0

High-throughput

0.249

Low

1309736

LPIN3
Phosphatidate phosphatase LPIN3

1

0

High-throughput

0.249

Low

1311599

TANC2
Protein TANC2

1

0

High-throughput

0.249

Low

1311602

FA53C
Protein FAM53C

1

0

High-throughput

0.249

Low

1311603

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

0

High-throughput

0.249

Low

1311604

CING
Cingulin

1

0

High-throughput

0.249

Low

1311610

PPM1H
Protein phosphatase 1H

1

0

High-throughput

0.249

Low

1311616

KCTD3
BTB/POZ domain-containing protein KCTD3

1

0

High-throughput

0.249

Low

1108484

NSN5B
Putative NOL1/NOP2/Sun domain family member 5B

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024