Protein: COX5B
Cytochrome c oxidase subunit 5B, mitochondrial (Cytochrome c oxidase polypeptide Vb)

Gene: COX5B
Organism: Homo sapiens
Interactions: 134
UniProt ID: P10606

Gene Ontology (top 5):
GO:0004129 - cytochrome-c oxidase activity
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005751 - mitochondrial respiratory chain complex IV
GO:0006123 - mitochondrial electron transport, cytochrome c to oxygen

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

495674

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

4

0

High-throughput

0.840

High

147648

COX7R
Cytochrome c oxidase subunit 7A-related protein, mitochondrial

1

1

High-throughput

0.691

High

495673

CX6A1
Cytochrome c oxidase subunit 6A1, mitochondrial

1

1

High-throughput

0.691

High

495683

CX7A1
Cytochrome c oxidase subunit 7A1, mitochondrial

1

1

High-throughput

0.691

High

495697

CDR2
Cerebellar degeneration-related protein 2

4

1

High-throughput

0.637

High

495686

TRI23
E3 ubiquitin-protein ligase TRIM23

3

1

High-throughput

0.613

High

495710

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

3

0

Small-scale

0.613

High

495769

TRIM1
Probable E3 ubiquitin-protein ligase MID2

3

3

High-throughput

0.604

High

495774

COA3
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial

2

0

High-throughput

0.585

High

204278

MS18B
Protein Mis18-beta

2

0

High-throughput

0.580

High

495676

TRI27
Zinc finger protein RFP

2

0

High-throughput

0.580

High

495693

MCCD1
Mitochondrial coiled-coil domain protein 1

2

0

High-throughput

0.580

High

495760

PKHF2
Pleckstrin homology domain-containing family F member 2

2

0

High-throughput

0.580

High

495763

PRDM6
Putative histone-lysine N-methyltransferase PRDM6

2

0

High-throughput

0.580

High

495669

TAU
Microtubule-associated protein tau

2

0

High-throughput

0.576

High

495706

KT33B
Keratin, type I cuticular Ha3-II

2

2

High-throughput

0.553

High

495720

K1C27
Keratin, type I cytoskeletal 27

2

2

High-throughput

0.553

High

495725

CDR2L
Cerebellar degeneration-related protein 2-like

2

1

High-throughput

0.553

High

495677

CX6B1
Cytochrome c oxidase subunit 6B1

1

1

High-throughput

0.536

High

495713

DPS1
All trans-polyprenyl-diphosphate synthase PDSS1

1

1

High-throughput

0.536

High

495680

K1C15
Keratin, type I cytoskeletal 15

1

3

High-throughput

0.523

High

495708

K1H1
Keratin, type I cuticular Ha1

1

2

High-throughput

0.523

High

368871

ESR1
Estrogen receptor

2

2

High-throughput

0.521

High

495681

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

3

High-throughput

0.515

High

261774

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

1

0

High-throughput

0.513

High

393995

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.513

High

495672

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

1

0

High-throughput

0.513

High

495675

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

1

0

High-throughput

0.513

High

495678

COX7C
Cytochrome c oxidase subunit 7C, mitochondrial

1

0

High-throughput

0.513

High

495692

DPOG1
DNA polymerase subunit gamma-1

1

0

High-throughput

0.513

High

495698

MMSA
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial

1

0

High-throughput

0.513

High

495704

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.513

High

495714

NDUF5
Arginine-hydroxylase NDUFAF5, mitochondrial

1

0

High-throughput

0.513

High

495726

NDUAB
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11

1

0

High-throughput

0.513

High

495733

ATPF2
ATP synthase mitochondrial F1 complex assembly factor 2

1

0

High-throughput

0.513

High

495739

CX7B2
Cytochrome c oxidase subunit 7B2, mitochondrial

1

0

High-throughput

0.513

High

495761

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.513

High

495762

RTN4
Reticulon-4

1

0

High-throughput

0.513

High

495764

COXM2
COX assembly mitochondrial protein 2 homolog

1

0

High-throughput

0.513

High

495738

SP7
Transcription factor Sp7

1

1

High-throughput

0.500

High

495682

AT2B4
Plasma membrane calcium-transporting ATPase 4

1

0

High-throughput

0.493

High

495723

DPP9
Dipeptidyl peptidase 9

1

1

High-throughput

0.489

High

495727

DLP1
All trans-polyprenyl-diphosphate synthase PDSS2

1

1

High-throughput

0.489

High

487074

ANDR
Androgen receptor

1

2

Small-scale

0.481

High

495750

KLF16
Krueppel-like factor 16

1

0

High-throughput

0.479

High

262684

CISY
Citrate synthase, mitochondrial

1

2

High-throughput

0.479

High

274475

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

3

High-throughput

0.479

High

276778

SCO1
Protein SCO1 homolog, mitochondrial

1

1

High-throughput

0.479

High

495701

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

1

High-throughput

0.479

High

495709

SURF1
Surfeit locus protein 1

1

1

High-throughput

0.479

High

495741

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

1

High-throughput

0.479

High

495746

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.479

High

495747

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.479

High

203863

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.458

High

325006

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

High-throughput

0.458

High

440311

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.458

High

455023

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

495670

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

495695

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

0

High-throughput

0.458

High

495707

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

495717

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

495721

MAVS
Mitochondrial antiviral-signaling protein

1

0

Small-scale

0.458

High

495742

OMA1
Metalloendopeptidase OMA1, mitochondrial

1

0

High-throughput

0.458

High

495743

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

0

High-throughput

0.458

High

495745

COX14
Cytochrome c oxidase assembly protein COX14

1

0

High-throughput

0.458

High

495748

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.458

High

495749

MIC26
MICOS complex subunit MIC26

1

0

High-throughput

0.458

High

495753

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

0

High-throughput

0.458

High

495756

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

495765

RMND1
Required for meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.458

High

495768

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

495773

ITM2B
Integral membrane protein 2B

1

1

High-throughput

0.457

High

377046

GCR
Glucocorticoid receptor

1

2

High-throughput

0.437

High

475270

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.437

High

495684

DPP4
Dipeptidyl peptidase 4

1

1

High-throughput

0.437

High

495705

TRI14
Tripartite motif-containing protein 14

1

2

High-throughput

0.437

High

495758

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

495715

TASO2
Protein TASOR 2

3

0

High-throughput

0.345

High

495729

IHO1
Interactor of HORMAD1 protein 1

2

0

High-throughput

0.334

High

146448

BHE40
Class E basic helix-loop-helix protein 40

2

0

High-throughput

0.327

High

495767

TFP11
Tuftelin-interacting protein 11

2

0

High-throughput

0.327

High

150119

BORG1
Cdc42 effector protein 2

2

0

High-throughput

0.316

High

279414

FLOT1
Flotillin-1

2

0

High-throughput

0.316

High

495685

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

2

0

High-throughput

0.316

High

495699

ARI5A
AT-rich interactive domain-containing protein 5A

2

0

High-throughput

0.316

High

495700

GOGA2
Golgin subfamily A member 2

2

0

High-throughput

0.316

High

495712

RBM48
RNA-binding protein 48

2

0

High-throughput

0.316

High

495719

DOK3
Docking protein 3

2

0

High-throughput

0.316

High

495722

SAXO4
Stabilizer of axonemal microtubules 4

2

0

High-throughput

0.316

High

495724

F228A
Protein FAM228A

2

0

High-throughput

0.316

High

495735

SLAI1
SLAIN motif-containing protein 1

2

0

High-throughput

0.316

High

495751

TEX12
Testis-expressed protein 12

2

0

High-throughput

0.316

High

495770

VPS28
Vacuolar protein sorting-associated protein 28 homolog

2

0

High-throughput

0.316

High

495771

NUDT5
ADP-sugar pyrophosphatase

2

0

High-throughput

0.316

High

495689

HD
Huntingtin

2

0

High-throughput

0.306

High

495702

TRAF1
TNF receptor-associated factor 1

1

0

High-throughput

0.299

High

495736

PNMA1
Paraneoplastic antigen Ma1

1

0

High-throughput

0.299

High

156780

FFAR1
Free fatty acid receptor 1

1

0

High-throughput

0.279

Low

495690

RAB5C
Ras-related protein Rab-5C

1

0

High-throughput

0.279

Low

495694

RAC1
Ras-related C3 botulinum toxin substrate 1

1

0

High-throughput

0.279

Low

495703

TOP3A
DNA topoisomerase 3-alpha

1

0

High-throughput

0.279

Low

495716

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

1

0

High-throughput

0.279

Low

495737

SPT20
Spermatogenesis-associated protein 20

1

0

High-throughput

0.279

Low

495740

YIPF5
Protein YIPF5

1

0

High-throughput

0.279

Low

495752

TX101
Testis-expressed protein 101

1

0

High-throughput

0.279

Low

495754

CF062
Uncharacterized protein C6orf62

1

0

High-throughput

0.279

Low

495766

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.279

Low

495772

EPDR1
Mammalian ependymin-related protein 1

1

0

High-throughput

0.279

Low

495730

FANCM
Fanconi anemia group M protein

1

0

High-throughput

0.269

Low

495731

PRR22
Proline-rich protein 22

1

0

High-throughput

0.251

Low

495775

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

0

High-throughput

0.251

Low

160346

AURKA
Aurora kinase A

1

0

High-throughput

0.249

Low

209616

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.249

Low

308353

KI20A
Kinesin-like protein KIF20A

1

0

High-throughput

0.249

Low

344927

CYTN
Cystatin-SN

1

0

Small-scale

0.249

Low

378951

MYCN
N-myc proto-oncogene protein

1

0

High-throughput

0.249

Low

390678

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

495671

EPB41
Protein 4.1

1

0

High-throughput

0.249

Low

495679

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.249

Low

495687

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

0

Small-scale

0.249

Low

495691

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

0

High-throughput

0.249

Low

495696

CDK5
Cyclin-dependent kinase 5

1

0

High-throughput

0.249

Low

495711

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

495728

NELFD
Negative elongation factor C/D

1

0

High-throughput

0.249

Low

495732

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.249

Low

495734

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.249

Low

495755

ATG5
Autophagy protein 5

1

0

Small-scale

0.249

Low

495759

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.249

Low

439055

ELNE
Neutrophil elastase

1

0

Small-scale

0.238

Low

495757

SAV1
Protein salvador homolog 1

1

0

Small-scale

0.238

Low

320961

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.232

Low

495688

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.232

Low

495718

SHLD3
Shieldin complex subunit 3

1

0

High-throughput

0.232

Low

495744

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024