Protein: NAMPT
Nicotinamide phosphoribosyltransferase (NAmPRTase) (Nampt) (EC 2.4.2.12) (Pre-B-cell colony-enhancing factor 1) (Pre-B cell-enhancing factor) (Visfatin)

Gene: NAMPT
Organism: Homo sapiens
Interactions: 105
UniProt ID: P43490

Gene Ontology (top 5):
GO:0005125 - cytokine activity
GO:0005829 - cytosol
GO:0007165 - signal transduction
GO:0007267 - cell-cell signaling
GO:0008284 - positive regulation of cell population proliferation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

796827

NAMPT
Nicotinamide phosphoribosyltransferase

2

1

Small-scale

0.820

High

796828

LEG7
Galectin-7

2

0

High-throughput

0.585

High

226771

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

346167

MYC
Myc proto-oncogene protein

2

0

High-throughput

0.559

High

364841

FRIL
Ferritin light chain

1

0

Small-scale

0.549

High

796885

SAR1B
Small COPII coat GTPase SAR1B

1

1

High-throughput

0.536

High

528729

CFTR
Cystic fibrosis transmembrane conductance regulator

2

0

High-throughput

0.528

High

686609

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.513

High

796861

MK15
Mitogen-activated protein kinase 15

1

0

High-throughput

0.513

High

796865

CUL5
Cullin-5

1

0

High-throughput

0.513

High

796869

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.513

High

664338

AA2AR
Adenosine receptor A2a

1

1

Small-scale

0.508

High

174695

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.501

High

364195

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.493

High

778970

CCNF
Cyclin-F

1

0

High-throughput

0.493

High

796848

P2RY6
P2Y purinoceptor 6

1

1

High-throughput

0.489

High

584522

GGT1
Glutathione hydrolase 1 proenzyme

1

0

Small-scale

0.486

High

177836

TMPS2
Transmembrane protease serine 2

1

2

High-throughput

0.479

High

429845

CATL1
Procathepsin L

1

1

High-throughput

0.479

High

435575

IGF1R
Insulin-like growth factor 1 receptor

1

3

High-throughput

0.479

High

453203

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

1

High-throughput

0.479

High

609204

FGFR3
Fibroblast growth factor receptor 3

1

1

High-throughput

0.479

High

641657

U2AF2
Splicing factor U2AF 65 kDa subunit

1

1

High-throughput

0.479

High

674358

UFO
Tyrosine-protein kinase receptor UFO

1

3

High-throughput

0.479

High

684486

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.479

High

796841

MERTK
Tyrosine-protein kinase Mer

1

3

High-throughput

0.479

High

796856

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.479

High

796866

FBXW7
F-box/WD repeat-containing protein 7

1

1

High-throughput

0.479

High

796870

MEP50
Methylosome protein WDR77

1

1

High-throughput

0.479

High

796881

FBW1B
F-box/WD repeat-containing protein 11

1

1

High-throughput

0.479

High

176569

FANCA
Fanconi anemia group A protein

1

0

Small-scale

0.460

High

682147

AKT2
RAC-beta serine/threonine-protein kinase

1

0

High-throughput

0.460

High

244069

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

298251

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

326493

SNAI1
Zinc finger protein SNAI1

1

0

High-throughput

0.458

High

373844

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

393091

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

0

High-throughput

0.458

High

456819

FURIN
Furin

1

0

High-throughput

0.458

High

503622

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

544947

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

569343

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

648680

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

718587

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

750166

COIL
Coilin

1

0

High-throughput

0.458

High

796829

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

796830

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

0

High-throughput

0.458

High

796831

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

796833

CD81
CD81 antigen

1

0

High-throughput

0.458

High

796834

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.458

High

796835

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

High-throughput

0.458

High

796836

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

High-throughput

0.458

High

796839

CREM
cAMP-responsive element modulator

1

0

Small-scale

0.458

High

796840

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

796843

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

796847

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

796852

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

796857

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

796864

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

796867

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

796871

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

796873

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

796875

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

796878

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

796879

TES
Testin

1

0

High-throughput

0.458

High

159029

UB2L6
Ubiquitin/ISG15-conjugating enzyme E2 L6

1

1

Small-scale

0.457

High

796876

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

384445

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.437

High

637224

CATS
Cathepsin S

1

1

High-throughput

0.437

High

796853

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

796862

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.437

High

796877

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.437

High

796880

XPO7
Exportin-7

1

1

High-throughput

0.437

High

796882

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.437

High

796850

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

796883

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.426

High

796858

TMM25
Transmembrane protein 25

3

0

High-throughput

0.347

High

796838

IFM3
Interferon-induced transmembrane protein 3

2

0

Small-scale

0.329

High

796854

UBP49
Ubiquitin carboxyl-terminal hydrolase 49

2

0

High-throughput

0.316

High

371072

NU1M
NADH-ubiquinone oxidoreductase chain 1

1

0

Small-scale

0.299

High

677894

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.279

Low

796845

I13R2
Interleukin-13 receptor subunit alpha-2

1

0

High-throughput

0.279

Low

796859

DAAF8
Dynein axonemal assembly factor 8

1

0

High-throughput

0.279

Low

796860

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.279

Low

796872

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.279

Low

796846

T132D
Transmembrane protein 132D

1

0

Small-scale

0.251

Low

259429

NIPS2
Protein NipSnap homolog 2

1

0

High-throughput

0.249

Low

328759

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.249

Low

329468

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

533424

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

552154

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

650590

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

719893

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

796832

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

796837

VIGLN
Vigilin

1

0

High-throughput

0.249

Low

796842

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.249

Low

796844

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.249

Low

796849

FBX43
F-box only protein 43

1

0

Small-scale

0.249

Low

796851

TET5C
Terminal nucleotidyltransferase 5C

1

0

High-throughput

0.249

Low

796855

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

796863

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

0

High-throughput

0.249

Low

796868

BROMI
Protein broad-minded

1

0

Small-scale

0.249

Low

796874

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

796884

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

789200

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024