Protein: THIC
Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Acetyl-CoA transferase-like protein) (Cytosolic acetoacetyl-CoA thiolase)

Gene: THIC, ACAT2
Organism: Homo sapiens
Interactions: 42
UniProt ID: Q9BWD1

Gene Ontology (top 5):
GO:0003985 - acetyl-CoA C-acetyltransferase activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006629 - lipid metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1314565

THIC
Acetyl-CoA acetyltransferase, cytosolic

2

7

High-throughput

0.791

High

623985

THIL
Acetyl-CoA acetyltransferase, mitochondrial

2

7

High-throughput

0.776

High

1252449

LNX1
E3 ubiquitin-protein ligase LNX

2

1

High-throughput

0.628

High

1313709

LST8
Target of rapamycin complex subunit LST8

2

4

High-throughput

0.611

High

1314569

WWOX
WW domain-containing oxidoreductase

2

1

High-throughput

0.606

High

869735

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.543

High

1314566

TX101
Testis-expressed protein 101

1

1

High-throughput

0.489

High

682007

AKT1
RAC-alpha serine/threonine-protein kinase

1

1

High-throughput

0.481

High

196342

PJA2
E3 ubiquitin-protein ligase Praja-2

1

3

Small-scale

0.479

High

228566

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

347787

MYC
Myc proto-oncogene protein

1

4

High-throughput

0.479

High

354546

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

2

High-throughput

0.479

High

601348

VDAC1
Voltage-dependent anion-selective channel protein 1

1

1

High-throughput

0.479

High

617651

CRCM
Colorectal mutant cancer protein

1

1

High-throughput

0.479

High

818420

SOX2
Transcription factor SOX-2

1

3

High-throughput

0.479

High

1024751

TRAF3
TNF receptor-associated factor 3

1

2

Small-scale

0.479

High

1130542

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

5

High-throughput

0.479

High

1171537

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

1267140

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

1314571

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1314572

TNIK
TRAF2 and NCK-interacting protein kinase

1

4

High-throughput

0.479

High

1314574

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

1

High-throughput

0.479

High

1314575

TRAF6
TNF receptor-associated factor 6

1

2

High-throughput

0.479

High

324599

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

926627

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

0

High-throughput

0.458

High

943802

CCNA1
Cyclin-A1

1

0

High-throughput

0.458

High

1314567

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

1314570

TRM7
tRNA

1

0

High-throughput

0.458

High

1314573

TPPC8
Trafficking protein particle complex subunit 8

1

0

High-throughput

0.458

High

497538

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.445

High

1291564

OTUB1
Ubiquitin thioesterase OTUB1

1

1

High-throughput

0.445

High

239615

EIF1B
Eukaryotic translation initiation factor 1b

1

2

High-throughput

0.437

High

385457

NTRK1
High affinity nerve growth factor receptor

1

10

High-throughput

0.437

High

553615

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.437

High

652144

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

721338

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

963678

E2F1
Transcription factor E2F1

1

0

High-throughput

0.426

High

735100

ZNF76
Zinc finger protein 76

2

0

High-throughput

0.316

High

1314568

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.279

Low

165874

KDM6B
Lysine-specific demethylase 6B

1

0

Small-scale

0.249

Low

881272

CTBP2
C-terminal-binding protein 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024