HitPredict
Protein: ANO1
Anoctamin-1 (Discovered on gastrointestinal stromal tumors protein 1) (Oral cancer overexpressed protein 2) (Transmembrane protein 16A) (Tumor-amplified and overexpressed sequence 2)

Gene: ANO1
Organism: Homo sapiens
Interactions: 10
UniProt ID: Q5XXA6

Gene Ontology (top 5):
GO:0005102 - signaling receptor binding
GO:0005227 - calcium-activated cation channel activity
GO:0005229 - intracellularly calcium-gated chloride channel activity
GO:0005247 - voltage-gated chloride channel activity
GO:0005254 - chloride channel activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score		 Confidence

783295

 TRI23
E3 ubiquitin-protein ligase TRIM23

1

3

Small-scale

 0.586

High

921691

 COPB
Coatomer subunit beta

1

1

Small-scale

 0.552

High

623385

 RO52
E3 ubiquitin-protein ligase TRIM21

1

0

Small-scale

 0.537

High

609704

 LEG3
Galectin-3

1

5

High-throughput

 0.536

High

691113

 1433T
14-3-3 protein theta

1

0

Small-scale

 0.529

High

1221036

 H2B1H
Histone H2B type 1-H

1

0

High-throughput

 0.493

High

159693

 DVL2
Segment polarity protein dishevelled homolog DVL-2

1

2

High-throughput

 0.479

High

1033017

 EWS
RNA-binding protein EWS

1

1

High-throughput

 0.479

High

563895

 CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

Small-scale

 0.458

High

1221035

 WDR59
GATOR2 complex protein WDR59

1

0

High-throughput

 0.279

Low

Service provided by Combinatics, Japan

Last updated: 11Aug2025