Protein: MMSA
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial (MMSDH) (EC 1.2.1.27) (Aldehyde dehydrogenase family 6 member A1) (Malonate-semialdehyde dehydrogenase [acylating])

Gene: MMSA, ALDH6A1
Organism: Homo sapiens
Interactions: 30
UniProt ID: Q02252

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0004491 - methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

396457

ALDH2
Aldehyde dehydrogenase, mitochondrial

3

14

High-throughput

0.861

High

970185

AL8A1
2-aminomuconic semialdehyde dehydrogenase

3

14

High-throughput

0.770

High

970181

ABRX1
BRCA1-A complex subunit Abraxas 1

2

0

High-throughput

0.602

High

970189

DPOG2
DNA polymerase subunit gamma-2

2

0

High-throughput

0.602

High

970178

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

3

High-throughput

0.584

High

496880

TAU
Microtubule-associated protein tau

1

6

High-throughput

0.536

High

254686

PTCD1
Pentatricopeptide repeat-containing protein 1, mitochondrial

1

0

High-throughput

0.513

High

258691

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

1

0

High-throughput

0.513

High

495698

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

1

0

High-throughput

0.513

High

574308

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.513

High

960041

HXC5
Homeobox protein Hox-C5

1

0

High-throughput

0.513

High

970180

FAHD1
Oxaloacetate decarboxylase, mitochondrial

1

0

High-throughput

0.513

High

970187

BEX4
Protein BEX4

1

0

High-throughput

0.513

High

174813

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

4

High-throughput

0.501

High

227212

PRKN
E3 ubiquitin-protein ligase parkin

1

10

High-throughput

0.479

High

970184

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

970188

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

638263

RBTN2
Rhombotin-2

1

0

High-throughput

0.460

High

503924

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

970177

RBM39
RNA-binding protein 39

1

0

High-throughput

0.458

High

970183

TM10C
tRNA methyltransferase 10 homolog C

1

0

Small-scale

0.458

High

970190

DUS12
Dual specificity protein phosphatase 12

1

0

High-throughput

0.458

High

970182

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

970186

BIRC6
Baculoviral IAP repeat-containing protein 6

1

4

Small-scale

0.437

High

814340

OR1D4
Olfactory receptor 1D4

1

2

High-throughput

0.407

High

527404

LAMP2
Lysosome-associated membrane glycoprotein 2

2

0

High-throughput

0.328

High

388874

CP1A1
Cytochrome P450 1A1

1

0

High-throughput

0.279

Low

812739

MSS4
Guanine nucleotide exchange factor MSS4

1

0

High-throughput

0.279

Low

970179

DB136
Defensin beta 136

1

0

High-throughput

0.279

Low

352072

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024