Protein: NACA
Nascent polypeptide-associated complex subunit alpha (NAC-alpha) (Alpha-NAC) (allergen Hom s 2)

Gene: NACA
Organism: Homo sapiens
Interactions: 197
UniProt ID: Q13765

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003231 - cardiac ventricle development
GO:0003677 - DNA binding
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

590906

BTF3
Transcription factor BTF3

10

20

Small-scale

0.971

High

1045198

BT3L4
Transcription factor BTF3 homolog 4

4

20

Small-scale

0.792

High

227401

PRKN
E3 ubiquitin-protein ligase parkin

3

2

High-throughput

0.656

High

166508

NACAD
NAC-alpha domain-containing protein 1

1

4

High-throughput

0.618

High

128557

DNM1L
Dynamin-1-like protein

2

1

High-throughput

0.611

High

233431

NUPR1
Nuclear protein 1

3

0

Small-scale

0.609

High

1026618

FADD
FAS-associated death domain protein

2

0

Small-scale

0.598

High

401970

JUN
Transcription factor Jun

2

2

Small-scale

0.597

High

770589

TXLNA
Alpha-taxilin

1

6

High-throughput

0.586

High

1041530

CUL3
Cullin-3

2

0

High-throughput

0.585

High

1045220

MET14
N6-adenosine-methyltransferase non-catalytic subunit

2

0

High-throughput

0.585

High

346734

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.584

High

1045214

NACA2
Nascent polypeptide-associated complex subunit alpha-2

1

4

Small-scale

0.575

High

369566

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

1045184

RHG24
Rho GTPase-activating protein 24

2

1

High-throughput

0.571

High

1045173

PPR18
Phostensin

1

2

Small-scale

0.561

High

934743

H31
Histone H3.1

2

0

High-throughput

0.559

High

905885

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

0

Small-scale

0.554

High

1045205

FUND2
FUN14 domain-containing protein 2

1

1

High-throughput

0.541

High

547797

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

1

High-throughput

0.536

High

555454

H2AX
Histone H2AX

1

1

High-throughput

0.536

High

586739

CSK22
Casein kinase II subunit alpha'

1

3

High-throughput

0.536

High

808121

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

4

High-throughput

0.536

High

1045201

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

1

High-throughput

0.536

High

1045225

SMYD2
N-lysine methyltransferase SMYD2

1

1

High-throughput

0.536

High

1045232

ZHX1
Zinc fingers and homeoboxes protein 1

1

0

High-throughput

0.518

High

394687

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.515

High

336491

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.513

High

363133

FINC
Fibronectin

1

0

High-throughput

0.513

High

452767

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

813445

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

850920

HDGF
Hepatoma-derived growth factor

1

0

High-throughput

0.513

High

1045221

ENY2
Transcription and mRNA export factor ENY2

1

0

High-throughput

0.513

High

1045239

EMC9
ER membrane protein complex subunit 9

1

0

High-throughput

0.513

High

345426

FOS
Protein c-Fos

1

2

Small-scale

0.501

High

1045242

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

2

Small-scale

0.501

High

849889

STA5B
Signal transducer and activator of transcription 5B

1

1

High-throughput

0.500

High

849933

APLP1
Amyloid beta precursor like protein 1

1

1

High-throughput

0.494

High

525241

UNG
Uracil-DNA glycosylase

1

0

High-throughput

0.493

High

890655

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

High-throughput

0.480

High

63074

RHG42
Rho GTPase-activating protein 42

1

1

High-throughput

0.479

High

125443

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

4

High-throughput

0.479

High

128170

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

1

High-throughput

0.479

High

232870

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

2

High-throughput

0.479

High

255143

ATG13
Autophagy-related protein 13

1

1

High-throughput

0.479

High

301807

TRI37
E3 ubiquitin-protein ligase TRIM37

1

3

High-throughput

0.479

High

374202

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

379381

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

397955

ISG15
Ubiquitin-like protein ISG15

1

3

High-throughput

0.479

High

475735

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

3

High-throughput

0.479

High

514003

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

1

High-throughput

0.479

High

552681

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

569702

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

578316

PGAM1
Phosphoglycerate mutase 1

1

1

High-throughput

0.479

High

614315

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

1

High-throughput

0.479

High

649499

RL10
Large ribosomal subunit protein uL16

1

2

High-throughput

0.479

High

654320

CALX
Calnexin

1

1

High-throughput

0.479

High

655360

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

2

High-throughput

0.479

High

666904

TKT
Transketolase

1

1

High-throughput

0.479

High

670018

MARCS
Myristoylated alanine-rich C-kinase substrate

1

2

High-throughput

0.479

High

749474

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.479

High

801874

RECQ1
ATP-dependent DNA helicase Q1

1

1

High-throughput

0.479

High

835737

GSK3B
Glycogen synthase kinase-3 beta

1

4

High-throughput

0.479

High

870793

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

1

High-throughput

0.479

High

871012

AAKG1
5'-AMP-activated protein kinase subunit gamma-1

1

1

High-throughput

0.479

High

871380

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

1

High-throughput

0.479

High

896077

UBC12
NEDD8-conjugating enzyme Ubc12

1

2

High-throughput

0.479

High

902570

SUMO2
Small ubiquitin-related modifier 2

1

3

High-throughput

0.479

High

908507

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

922160

RL31
Large ribosomal subunit protein eL31

1

1

High-throughput

0.479

High

934155

CSK21
Casein kinase II subunit alpha

1

7

High-throughput

0.479

High

946234

BASP1
Brain acid soluble protein 1

1

2

High-throughput

0.479

High

959405

VIGLN
Vigilin

1

3

High-throughput

0.479

High

961543

FKBP3
Peptidyl-prolyl cis-trans isomerase FKBP3

1

4

High-throughput

0.479

High

1025737

TADBP
TAR DNA-binding protein 43

1

2

High-throughput

0.479

High

1026404

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.479

High

1045156

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.479

High

1045157

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

1045160

TEBP
Prostaglandin E synthase 3

1

3

High-throughput

0.479

High

1045161

PCBP1
Poly(rC)-binding protein 1

1

2

Small-scale

0.479

High

1045164

LARP7
La-related protein 7

1

2

High-throughput

0.479

High

1045166

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.479

High

1045176

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1045178

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

4

High-throughput

0.479

High

1045183

RPTOR
Regulatory-associated protein of mTOR

1

1

High-throughput

0.479

High

1045190

LMO7
LIM domain only protein 7

1

2

Small-scale

0.479

High

1045192

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

1045193

HS105
Heat shock protein 105 kDa

1

3

High-throughput

0.479

High

1045194

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

1045195

CSN5
COP9 signalosome complex subunit 5

1

1

High-throughput

0.479

High

1045202

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.479

High

1045203

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

2

High-throughput

0.479

High

1045204

PBDC1
Protein PBDC1

1

1

Small-scale

0.479

High

1045206

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

1

High-throughput

0.479

High

1045209

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

2

High-throughput

0.479

High

1045210

RHG39
Rho GTPase-activating protein 39

1

1

High-throughput

0.479

High

1045217

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.479

High

1045223

BRD7
Bromodomain-containing protein 7

1

1

High-throughput

0.479

High

1045226

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

1

High-throughput

0.479

High

1045227

HDAC6
Histone deacetylase 6

1

1

High-throughput

0.479

High

1045228

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1045230

FBW1B
F-box/WD repeat-containing protein 11

1

2

High-throughput

0.479

High

1045235

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.479

High

1045236

FAF1
FAS-associated factor 1

1

1

High-throughput

0.479

High

1045240

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.479

High

1045241

MB212
Protein mab-21-like 2

1

1

High-throughput

0.479

High

1045243

RBM8A
RNA-binding protein 8A

1

2

High-throughput

0.479

High

489588

OSTP
Osteopontin

1

0

Small-scale

0.460

High

962773

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

High-throughput

0.460

High

128732

RTCA
RNA 3'-terminal phosphate cyclase

1

0

High-throughput

0.458

High

161368

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

0

Small-scale

0.458

High

209967

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

224428

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.458

High

239130

CTND1
Catenin delta-1

1

0

Small-scale

0.458

High

244410

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

282644

RNF8
E3 ubiquitin-protein ligase RNF8

1

0

High-throughput

0.458

High

298499

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

303222

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

313818

SVIL
Supervillin

1

0

Small-scale

0.458

High

504050

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

557379

BGAL
Beta-galactosidase

1

0

Small-scale

0.458

High

562925

STMN1
Stathmin

1

0

High-throughput

0.458

High

596476

PTMS
Parathymosin

1

0

High-throughput

0.458

High

651158

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

671656

PEBP1
Phosphatidylethanolamine-binding protein 1

1

0

High-throughput

0.458

High

724232

MSX2
Homeobox protein MSX-2

1

0

High-throughput

0.458

High

821761

NEST
Nestin

1

0

Small-scale

0.458

High

823985

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

832441

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

900151

RL37A
Large ribosomal subunit protein eL43

1

0

High-throughput

0.458

High

903211

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.458

High

949679

RL36A
Large ribosomal subunit protein eL42

1

0

High-throughput

0.458

High

967162

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

973062

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.458

High

998687

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

1016168

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.458

High

1026263

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.458

High

1035707

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1045152

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.458

High

1045158

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1045159

PLEC
Plectin

1

0

High-throughput

0.458

High

1045162

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1045163

CDC37
Hsp90 co-chaperone Cdc37

1

0

Small-scale

0.458

High

1045169

TET5C
Terminal nucleotidyltransferase 5C

1

0

High-throughput

0.458

High

1045170

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1045171

CYTSA
Cytospin-A

1

0

Small-scale

0.458

High

1045177

DPPA4
Developmental pluripotency-associated protein 4

1

0

High-throughput

0.458

High

1045179

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1045181

ZNG1B
Zinc-regulated GTPase metalloprotein activator 1B

1

0

High-throughput

0.458

High

1045182

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.458

High

1045187

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.458

High

1045188

MORC4
MORC family CW-type zinc finger protein 4

1

0

High-throughput

0.458

High

1045191

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.458

High

1045196

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1045199

NEB2
Neurabin-2

1

0

Small-scale

0.458

High

1045200

PARK7
Parkinson disease protein 7

1

0

High-throughput

0.458

High

1045207

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

1045208

TRI31
E3 ubiquitin-protein ligase TRIM31

1

0

High-throughput

0.458

High

1045213

EGLN1
Egl nine homolog 1

1

0

Small-scale

0.458

High

1045216

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

1045218

RC3H2
Roquin-2

1

0

High-throughput

0.458

High

1045219

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.458

High

1045229

UBQL2
Ubiquilin-2

1

0

High-throughput

0.458

High

1045237

SYFA
Phenylalanine--tRNA ligase alpha subunit

1

0

High-throughput

0.458

High

496987

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.445

High

1045172

PKHA7
Pleckstrin homology domain-containing family A member 7

1

5

High-throughput

0.445

High

1045168

RIF1
Telomere-associated protein RIF1

1

0

High-throughput

0.438

High

384809

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

531821

PDIA4
Protein disulfide-isomerase A4

1

2

High-throughput

0.437

High

1045153

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

2

High-throughput

0.437

High

1045154

RBM39
RNA-binding protein 39

1

1

High-throughput

0.437

High

1045180

ZCH18
Zinc finger CCCH domain-containing protein 18

1

2

High-throughput

0.437

High

1045185

FXL13
F-box and leucine-rich repeat protein 13

1

1

Small-scale

0.437

High

1045186

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.437

High

1045211

DDX24
ATP-dependent RNA helicase DDX24

1

1

High-throughput

0.437

High

1045233

PKHG1
Pleckstrin homology domain-containing family G member 1

1

1

High-throughput

0.437

High

1045234

HECD1
E3 ubiquitin-protein ligase HECTD1

1

2

High-throughput

0.437

High

1045238

NINL
Ninein-like protein

1

1

High-throughput

0.437

High

230622

KATIP
Katanin-interacting protein

1

0

High-throughput

0.426

High

275418

PR15A
Protein phosphatase 1 regulatory subunit 15A

1

0

High-throughput

0.426

High

321072

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.426

High

581718

VCAM1
Vascular cell adhesion protein 1

1

0

High-throughput

0.426

High

931148

YBOX1
Y-box-binding protein 1

1

0

High-throughput

0.426

High

1045165

Q5JYA6
PLEKHG1

1

1

High-throughput

0.407

High

1045197

IGS21
Immunoglobulin superfamily member 21

1

0

High-throughput

0.282

High

1045212

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

0

High-throughput

0.282

High

1045155

CND2
Condensin complex subunit 2

1

0

High-throughput

0.279

Low

1045167

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.251

Low

148784

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

720416

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1045174

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.249

Low

1045189

NOC3L
Nucleolar complex protein 3 homolog

1

0

High-throughput

0.249

Low

1045222

NGB
Neuroglobin

1

0

High-throughput

0.249

Low

1045224

ANLN
Anillin

1

0

High-throughput

0.249

Low

1045231

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.249

Low

1045175

SHLD3
Shieldin complex subunit 3

1

0

High-throughput

0.232

Low

1045215

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024