HitPredict - High confidence protein-protein interactions

Protein: NALP4
NACHT, LRR and PYD domains-containing protein 4 (Cancer/testis antigen 58) (CT58) (PAAD and NACHT-containing protein 2) (PAN2) (PYRIN and NACHT-containing protein 2) (PYRIN-containing APAF1-like protein 4) (PYPAF4) (Ribonuclease inhibitor 2)

Gene: NALP4, NLRP4
Organism: Homo sapiens
Interactions: 8
UniProt ID: Q96MN2

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006954 - inflammatory response
GO:0045824 - negative regulation of innate immune response

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
1398259	TBK1 Serine/threonine-protein kinase TBK1	2	14	Small-scale	0.754	High
177926	IKKA Inhibitor of nuclear factor kappa-B kinase subunit alpha	1	14	Small-scale	0.618	High
1398258	NLRC4 NLR family CARD domain-containing protein 4	1	19	Small-scale	0.618	High
1398261	SGT1 Protein SGT1 homolog	2	13	Small-scale	0.612	High
1201301	PYDC2 Pyrin domain-containing protein 2	1	18	Small-scale	0.590	High
461825	HS90A Heat shock protein HSP 90-alpha	1	12	Small-scale	0.479	High
1398260	DTX4 E3 ubiquitin-protein ligase DTX4	1	1	Small-scale	0.479	High
1227277	A16L1 Autophagy-related protein 16-1	1	7	High-throughput	0.445	High

Service provided by Combinatics, Japan

Last updated: 11Aug2025