Protein: DPOE3
DNA polymerase epsilon subunit 3 (Arsenic-transactivated protein) (AsTP) (Chromatin accessibility complex 17 kDa protein) (CHRAC-17) (HuCHRAC17) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17)

Gene: DPOE3, POLE3
Organism: Homo sapiens
Interactions: 45
UniProt ID: Q9NRF9

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003887 - DNA-directed DNA polymerase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005721 - pericentric heterochromatin

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1344716

CHRC1
Chromatin accessibility complex protein 1

6

20

Small-scale

0.958

High

1060236

NC2A
Dr1-associated corepressor

5

20

High-throughput

0.937

High

966205

NC2B
Protein Dr1

5

10

High-throughput

0.924

High

1344241

DPOE4
DNA polymerase epsilon subunit 4

4

20

Small-scale

0.902

High

229503

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

5

4

Small-scale

0.721

High

1344717

BAZ1A
Bromodomain adjacent to zinc finger domain protein 1A

4

12

Small-scale

0.692

High

1087426

H2B2E
Histone H2B type 2-E

1

5

High-throughput

0.691

High

992322

DPOE1
DNA polymerase epsilon catalytic subunit A

4

2

Small-scale

0.691

High

880363

DPOE2
DNA polymerase epsilon subunit 2

3

1

Small-scale

0.689

High

1145545

Q658N3
Protein Dr1

1

10

High-throughput

0.665

High

658740

SMCA1
Probable global transcription activator SNF2L1

2

4

High-throughput

0.628

High

707762

H2B1B
Histone H2B type 1-B

1

5

High-throughput

0.618

High

273489

PPM1B
Protein phosphatase 1B

1

1

High-throughput

0.536

High

317524

YETS4
YEATS domain-containing protein 4

1

4

High-throughput

0.536

High

996915

SSRP1
FACT complex subunit SSRP1

1

1

High-throughput

0.536

High

1033403

ORC1
Origin recognition complex subunit 1

1

2

High-throughput

0.536

High

1261303

RN138
E3 ubiquitin-protein ligase RNF138

1

1

High-throughput

0.536

High

1316329

GNB1L
Guanine nucleotide-binding protein subunit beta-like protein 1

1

3

High-throughput

0.536

High

565043

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.513

High

1240575

SCPDL
Saccharopine dehydrogenase-like oxidoreductase

1

0

High-throughput

0.513

High

1328685

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

0

High-throughput

0.513

High

1129404

WIPI3
WD repeat domain phosphoinositide-interacting protein 3

1

3

High-throughput

0.489

High

1296087

DNJC1
DnaJ homolog subfamily C member 1

1

1

High-throughput

0.489

High

244986

BRD4
Bromodomain-containing protein 4

1

8

High-throughput

0.479

High

279045

RAD17
Cell cycle checkpoint protein RAD17

1

2

Small-scale

0.479

High

570102

CEBPB
CCAAT/enhancer-binding protein beta

1

3

High-throughput

0.479

High

880830

HDAC4
Histone deacetylase 4

1

2

High-throughput

0.479

High

917996

H4
Histone H4

1

3

High-throughput

0.479

High

1344720

YETS2
YEATS domain-containing protein 2

1

5

Small-scale

0.479

High

295294

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

525078

XRCC5
X-ray repair cross-complementing protein 5

1

0

Small-scale

0.458

High

1267180

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1332657

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1344719

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

395864

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.457

High

203072

ERI3
ERI1 exoribonuclease 3

1

0

High-throughput

0.279

Low

253277

KI21B
Kinesin-like protein KIF21B

1

0

High-throughput

0.279

Low

895383

RAB5B
Ras-related protein Rab-5B

1

0

High-throughput

0.279

Low

919676

RAP1A
Ras-related protein Rap-1A

1

0

High-throughput

0.279

Low

1159533

SCYL2
SCY1-like protein 2

1

0

High-throughput

0.279

Low

1201071

PNM8A
Paraneoplastic antigen-like protein 8A

1

0

High-throughput

0.279

Low

1230976

LRC47
Leucine-rich repeat-containing protein 47

1

0

High-throughput

0.279

Low

1336681

CHM1A
Charged multivesicular body protein 1a

1

0

High-throughput

0.279

Low

1344718

GDAP2
Ganglioside-induced differentiation-associated protein 2

1

0

High-throughput

0.279

Low

1171870

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024