Protein: NFE2
Transcription factor NF-E2 45 kDa subunit (Leucine zipper protein NF-E2) (Nuclear factor, erythroid-derived 2 45 kDa subunit) (p45 NF-E2)

Gene: NFE2
Organism: Mus musculus
Interactions: 75
UniProt ID: Q07279

Gene Ontology (top 5):
GO:0000768 - syncytium formation by plasma membrane fusion
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

236426

MAFG
Transcription factor MafG

1

19

Small-scale

0.647

High

1059003

MAFK
Transcription factor MafK

1

20

Small-scale

0.618

High

1059024

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

2

4

Small-scale

0.614

High

1009383

C2TA
MHC class II transactivator

1

1

High-throughput

0.568

High

205747

PER1
Period circadian protein homolog 1

1

4

High-throughput

0.541

High

236727

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

3

High-throughput

0.541

High

312490

NEMO
NF-kappa-B essential modulator

1

2

High-throughput

0.541

High

449209

HXA4
Homeobox protein Hox-A4

1

7

High-throughput

0.541

High

520657

HXB4
Homeobox protein Hox-B4

1

7

High-throughput

0.541

High

833808

KDM5C
Lysine-specific demethylase 5C

1

6

High-throughput

0.541

High

999970

PDLI4
PDZ and LIM domain protein 4

1

1

High-throughput

0.541

High

1000333

DLX5
Homeobox protein DLX-5

1

4

High-throughput

0.541

High

1034860

SNAI1
Zinc finger protein SNAI1

1

2

High-throughput

0.541

High

1058981

ZSCA2
Zinc finger and SCAN domain-containing protein 2

1

1

High-throughput

0.541

High

1059001

REQU
Zinc finger protein ubi-d4

1

8

High-throughput

0.541

High

1059007

ZN219
Zinc finger protein 219

1

3

High-throughput

0.541

High

1059008

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

9

High-throughput

0.541

High

1059009

MBB1A
Myb-binding protein 1A

1

1

High-throughput

0.541

High

1059011

ZN592
Zinc finger protein 592

1

2

High-throughput

0.541

High

1059016

E4F1
Transcription factor E4F1

1

5

High-throughput

0.541

High

1059017

ERCC8
DNA excision repair protein ERCC-8

1

6

High-throughput

0.541

High

1059019

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

2

High-throughput

0.541

High

1059020

ANR49
Ankyrin repeat domain-containing protein 49

1

3

High-throughput

0.541

High

1059022

KDM4B
Lysine-specific demethylase 4B

1

4

High-throughput

0.541

High

1059027

PLRG1
Pleiotropic regulator 1

1

9

High-throughput

0.541

High

1059028

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

2

High-throughput

0.541

High

1059030

ASH1L
Histone-lysine N-methyltransferase ASH1L

1

4

High-throughput

0.541

High

1059034

MMS19
MMS19 nucleotide excision repair protein homolog

1

1

High-throughput

0.541

High

1059040

KAT2B
Histone acetyltransferase KAT2B

1

11

High-throughput

0.541

High

1059041

RNF14
E3 ubiquitin-protein ligase RNF14

1

4

High-throughput

0.541

High

1059046

TLE6
Transducin-like enhancer protein 6

1

5

High-throughput

0.541

High

1059048

ZN292
Zinc finger protein 292

1

2

High-throughput

0.541

High

1059047

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

1

Small-scale

0.536

High

98178

ZN277
Zinc finger protein 277

1

0

High-throughput

0.518

High

98220

E9Q7L6
Forkhead box N2

1

0

High-throughput

0.518

High

886365

HCLS1
Hematopoietic lineage cell-specific protein

1

0

High-throughput

0.518

High

1000094

TIAR
Nucleolysin TIAR

1

0

High-throughput

0.518

High

1059000

ORC2
Origin recognition complex subunit 2

1

0

High-throughput

0.518

High

1059002

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.518

High

1059005

AEBP1
Adipocyte enhancer-binding protein 1

1

0

High-throughput

0.518

High

1059010

UBIP1
Upstream-binding protein 1

1

0

High-throughput

0.518

High

1059012

GCFC2
Intron Large complex component GCFC2

1

0

High-throughput

0.518

High

1059013

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.518

High

1059018

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

High-throughput

0.518

High

1059021

CARTF
Calcium-responsive transcription factor

1

0

High-throughput

0.518

High

1059026

CSDC2
Cold shock domain-containing protein C2

1

0

High-throughput

0.518

High

1059031

PBX4
Pre-B-cell leukemia transcription factor 4

1

0

High-throughput

0.518

High

1059033

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

High-throughput

0.518

High

1059037

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

High-throughput

0.518

High

1059039

TF2H1
General transcription factor IIH subunit 1

1

0

High-throughput

0.518

High

1059042

TF2H2
General transcription factor IIH subunit 2

1

0

High-throughput

0.518

High

1059043

TRIP4
Activating signal cointegrator 1

1

0

High-throughput

0.518

High

1059004

KDM5D
Lysine-specific demethylase 5D

1

6

High-throughput

0.494

High

1059023

CSDE1
Cold shock domain-containing protein E1

1

1

High-throughput

0.494

High

1059032

ZDHC6
Palmitoyltransferase ZDHHC6

1

1

High-throughput

0.494

High

1059036

ASB12
Ankyrin repeat and SOCS box protein 12

1

2

High-throughput

0.494

High

1059045

ASB1
Ankyrin repeat and SOCS box protein 1

1

2

High-throughput

0.494

High

1059015

Q8C964
Zinc finger protein 764

1

5

High-throughput

0.481

High

1059029

Q99K53
Zfp111 protein

1

3

High-throughput

0.481

High

107066

F8VPR5
histone acetyltransferase

1

14

Small-scale

0.479

High

204487

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

1

Small-scale

0.479

High

644300

TAL1
T-cell acute lymphocytic leukemia protein 1 homolog

1

2

High-throughput

0.479

High

965384

WDR5
WD repeat-containing protein 5

1

6

Small-scale

0.479

High

1059006

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

11

High-throughput

0.479

High

1059014

RBBP5
Retinoblastoma-binding protein 5

1

7

Small-scale

0.479

High

1059025

MK08
Mitogen-activated protein kinase 8

1

13

Small-scale

0.479

High

312584

MEN1
Menin

1

0

Small-scale

0.458

High

98287

E9QAP1
Zinc finger protein 764

1

5

High-throughput

0.457

High

1059044

Q9R164
Zinc finger protein 111

1

3

High-throughput

0.457

High

838212

STAT1
Signal transducer and activator of transcription 1

1

3

Small-scale

0.445

High

1058999

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

2

Small-scale

0.445

High

993455

SPT4A
Transcription elongation factor SPT4-A

1

0

High-throughput

0.282

High

1059035

T2EA
General transcription factor IIE subunit 1

1

0

High-throughput

0.282

High

1059038

T2EB
General transcription factor IIE subunit 2

1

0

High-throughput

0.282

High

475179

HEM0
5-aminolevulinate synthase, erythroid-specific, mitochondrial

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025