Protein: PROS
Vitamin K-dependent protein S

Gene: PROS, PROS1
Organism: Homo sapiens
Interactions: 47
UniProt ID: P07225

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0004866 - endopeptidase inhibitor activity
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

423072

C4BPB
C4b-binding protein beta chain

4

5

Small-scale

0.696

High

252735

FCG3B
Low affinity immunoglobulin gamma Fc region receptor III-B

1

20

High-throughput

0.691

High

305235

NXPH3
Neurexophilin-3

1

8

High-throughput

0.691

High

375828

PROC
Vitamin K-dependent protein C

1

17

High-throughput

0.691

High

423094

SIRPD
Signal-regulatory protein delta

1

4

High-throughput

0.691

High

423086

ZPBP2
Zona pellucida-binding protein 2

3

0

High-throughput

0.638

High

423087

LYZL2
Lysozyme-like protein 2

2

4

High-throughput

0.628

High

423067

FA5
Coagulation factor V

2

11

Small-scale

0.602

High

423092

TECT2
Tectonic-2

2

1

High-throughput

0.574

High

380896

VWF
von Willebrand factor

1

17

Small-scale

0.561

High

217374

VEGFD
Vascular endothelial growth factor D

1

4

High-throughput

0.536

High

318343

ECEL1
Endothelin-converting enzyme-like 1

1

1

High-throughput

0.536

High

319490

LY86
Lymphocyte antigen 86

1

8

High-throughput

0.536

High

389432

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

3

High-throughput

0.536

High

423065

PAEP
Glycodelin

1

2

High-throughput

0.536

High

423066

CFC1
Cryptic protein

1

7

High-throughput

0.536

High

423068

BMP4
Bone morphogenetic protein 4

1

12

High-throughput

0.536

High

423069

PRG2
Bone marrow proteoglycan

1

17

High-throughput

0.536

High

423070

EDN3
Endothelin-3

1

4

High-throughput

0.536

High

423073

WNT5A
Protein Wnt-5a

1

6

High-throughput

0.536

High

423074

TFPI2
Tissue factor pathway inhibitor 2

1

6

High-throughput

0.536

High

423075

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

4

High-throughput

0.536

High

423078

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

2

High-throughput

0.536

High

423080

ADIPO
Adiponectin

1

20

High-throughput

0.536

High

423082

DB136
Defensin beta 136

1

1

High-throughput

0.536

High

423083

GRPL2
GLIPR1-like protein 2

1

4

High-throughput

0.536

High

423085

LYZL1
Lysozyme-like protein 1

1

4

High-throughput

0.536

High

423090

ESPB1
Epididymal sperm-binding protein 1

1

12

High-throughput

0.536

High

423093

LCFC1
Sperm-egg fusion protein LLCFC1

1

7

High-throughput

0.536

High

423095

CST11
Cystatin-11

1

11

High-throughput

0.536

High

423071

KPCA
Protein kinase C alpha type

1

4

High-throughput

0.515

High

423076

1433G
14-3-3 protein gamma

1

5

High-throughput

0.515

High

423077

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

4

High-throughput

0.515

High

423084

Q5SUL5
HLA class I histocompatibility antigen A alpha chain

1

2

High-throughput

0.515

High

423091

OPTN
Optineurin

1

13

High-throughput

0.515

High

336805

FA8
Coagulation factor VIII

1

9

Small-scale

0.501

High

423096

SDF2L
Stromal cell-derived factor 2-like protein 1

1

9

High-throughput

0.489

High

423064

RSSA
Small ribosomal subunit protein uS2

1

1

High-throughput

0.481

High

204935

TGON2
Trans-Golgi network integral membrane protein 2

1

20

High-throughput

0.479

High

423079

SETB1
Histone-lysine N-methyltransferase SETDB1

1

4

High-throughput

0.470

High

423089

KAT5
Histone acetyltransferase KAT5

1

1

High-throughput

0.470

High

423098

TBK1
Serine/threonine-protein kinase TBK1

1

3

High-throughput

0.439

High

260457

PITX3
Pituitary homeobox 3

1

3

Small-scale

0.437

High

417849

NPM
Nucleophosmin

1

4

High-throughput

0.437

High

423081

E2F4
Transcription factor E2F4

1

1

High-throughput

0.437

High

423097

FBX6
F-box only protein 6

1

20

High-throughput

0.437

High

423088

LMO3
LIM domain only protein 3

1

0

High-throughput

0.268

Low


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Last updated: 15 Jul 2024