Protein: UBP12
Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.4.19.12) (Deubiquitinating enzyme 12) (Ubiquitin thioesterase 12) (Ubiquitin-hydrolyzing enzyme 1) (Ubiquitin-specific-processing protease 12)

Gene: UBP12, USP12
Organism: Homo sapiens
Interactions: 66
UniProt ID: O75317

Gene Ontology (top 5):
GO:0004197 - cysteine-type endopeptidase activity
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

259296

WDR48
WD repeat-containing protein 48

11

12

Small-scale

0.976

High

259297

WDR20
WD repeat-containing protein 20

11

16

Small-scale

0.974

High

259273

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

3

14

Small-scale

0.839

High

259279

DMWD
Dystrophia myotonica WD repeat-containing protein

3

17

Small-scale

0.839

High

232744

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

4

5

Small-scale

0.694

High

259312

VSX1
Visual system homeobox 1

3

3

High-throughput

0.670

High

259271

VSX2
Visual system homeobox 2

3

3

High-throughput

0.667

High

259287

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

1

16

High-throughput

0.665

High

259292

PHLP2
PH domain leucine-rich repeat-containing protein phosphatase 2

3

5

Small-scale

0.662

High

259261

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

20

Small-scale

0.647

High

259262

ANDR
Androgen receptor

3

9

Small-scale

0.640

High

259291

RN19B
E3 ubiquitin-protein ligase RNF19B

2

8

High-throughput

0.628

High

259295

TSYL6
Testis-specific Y-encoded-like protein 6

2

5

High-throughput

0.628

High

259306

GORS1
Golgi reassembly-stacking protein 1

2

1

High-throughput

0.628

High

259302

R51A1
RAD51-associated protein 1

2

1

High-throughput

0.621

High

259256

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

18

High-throughput

0.618

High

259301

DCAF4
DDB1- and CUL4-associated factor 4

1

1

High-throughput

0.618

High

259305

MEP50
Methylosome protein WDR77

1

9

Small-scale

0.618

High

259310

WDR26
WD repeat-containing protein 26

1

9

Small-scale

0.618

High

259294

GP161
G-protein coupled receptor 161

2

0

High-throughput

0.602

High

259307

HSPB9
Heat shock protein beta-9

2

0

High-throughput

0.602

High

259266

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.601

High

259272

1433G
14-3-3 protein gamma

2

20

High-throughput

0.601

High

259277

1433F
14-3-3 protein eta

2

20

High-throughput

0.601

High

259303

ITCH
E3 ubiquitin-protein ligase Itchy homolog

2

4

Small-scale

0.584

High

259278

BAX
Apoptosis regulator BAX

1

1

Small-scale

0.573

High

259260

HMGB1
High mobility group protein B1

1

1

Small-scale

0.561

High

259300

Q8WUW6
DMWD protein

1

7

High-throughput

0.553

High

259265

CD6
T-cell differentiation antigen CD6

1

1

High-throughput

0.536

High

259288

SGO1
Shugoshin 1

1

1

High-throughput

0.536

High

259299

IGDC4
Immunoglobulin superfamily DCC subclass member 4

1

1

High-throughput

0.536

High

259304

OPALI
Opalin

1

1

High-throughput

0.536

High

259314

HSPB8
Heat shock protein beta-8

1

1

High-throughput

0.536

High

259316

PHF8
Histone lysine demethylase PHF8

1

4

High-throughput

0.536

High

259259

MMP2
72 kDa type IV collagenase

1

2

High-throughput

0.515

High

259282

ILF3
Interleukin enhancer-binding factor 3

1

6

High-throughput

0.515

High

259284

DHX8
ATP-dependent RNA helicase DHX8

1

4

High-throughput

0.515

High

259308

CAB45
45 kDa calcium-binding protein

1

2

High-throughput

0.515

High

259309

PAIP1
Polyadenylate-binding protein-interacting protein 1

1

2

High-throughput

0.515

High

259317

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

6

High-throughput

0.515

High

259267

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.515

High

259298

NEK7
Serine/threonine-protein kinase Nek7

1

6

High-throughput

0.515

High

259275

X3CL1
Fractalkine

1

0

High-throughput

0.513

High

259289

CDC73
Parafibromin

1

0

Small-scale

0.504

High

259258

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

259269

NOTC1
Neurogenic locus notch homolog protein 1

1

4

Small-scale

0.501

High

259285

H2A2C
Histone H2A type 2-C

1

14

Small-scale

0.501

High

259286

H2B2E
Histone H2B type 2-E

1

16

Small-scale

0.501

High

259281

NU160
Nuclear pore complex protein Nup160

1

0

High-throughput

0.493

High

259264

CALR
Calreticulin

1

0

High-throughput

0.493

High

259315

PNMA2
Paraneoplastic antigen Ma2

1

2

High-throughput

0.489

High

254527

CLAP2
CLIP-associating protein 2

1

2

High-throughput

0.479

High

259257

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

High-throughput

0.479

High

259268

ZAP70
Tyrosine-protein kinase ZAP-70

1

5

Small-scale

0.479

High

259270

MMP14
Matrix metalloproteinase-14

1

2

Small-scale

0.479

High

259274

GRB2
Growth factor receptor-bound protein 2

1

6

Small-scale

0.479

High

259276

MDM2
E3 ubiquitin-protein ligase Mdm2

1

5

Small-scale

0.479

High

259280

EP300
Histone acetyltransferase p300

1

4

Small-scale

0.479

High

259283

CBLB
E3 ubiquitin-protein ligase CBL-B

1

3

Small-scale

0.479

High

259313

Q9P1S2
HDCMD34P

1

3

High-throughput

0.479

High

207399

LAT
Linker for activation of T-cells family member 1

1

0

Small-scale

0.458

High

259255

PPM1B
Protein phosphatase 1B

1

0

Small-scale

0.458

High

259290

TRAT1
T-cell receptor-associated transmembrane adapter 1

1

0

Small-scale

0.458

High

259311

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.458

High

259293

MAVS
Mitochondrial antiviral-signaling protein

1

3

Small-scale

0.437

High

259263

MK
Midkine

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024