Protein: NKG2D
NKG2-D type II integral membrane protein (Killer cell lectin-like receptor subfamily K member 1) (NK cell receptor D) (NKG2-D-activating NK receptor) (CD antigen CD314)

Gene: NKG2D, KLRK1
Organism: Homo sapiens
Interactions: 30
UniProt ID: P26718

Gene Ontology (top 5):
GO:0002223 - stimulatory C-type lectin receptor signaling pathway
GO:0002250 - adaptive immune response
GO:0005886 - plasma membrane
GO:0006809 - nitric oxide biosynthetic process
GO:0007165 - signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

644716

ULBP5
UL-16 binding protein 5

4

20

Small-scale

0.878

High

644718

RAE1E
Retinoic acid early transcript 1E

4

20

Small-scale

0.878

High

644721

ULBP3
UL16-binding protein 3

3

20

Small-scale

0.840

High

644714

ULBP6
UL16-binding protein 6

2

20

Small-scale

0.789

High

644710

MICA
MHC class I polypeptide-related sequence A

2

20

Small-scale

0.778

High

644722

ULBP2
UL16-binding protein 2

2

20

Small-scale

0.768

High

644703

NKG2D
NKG2-D type II integral membrane protein

1

17

Small-scale

0.647

High

644723

ULBP1
UL16-binding protein 1

1

20

Small-scale

0.647

High

644728

SE1L1
Protein sel-1 homolog 1

1

9

High-throughput

0.618

High

644727

HCST
Hematopoietic cell signal transducer

2

2

Small-scale

0.584

High

644704

CALX
Calnexin

1

20

High-throughput

0.536

High

644705

ACSL1
Long-chain-fatty-acid--CoA ligase 1

1

6

High-throughput

0.536

High

644708

PRKDC
DNA-dependent protein kinase catalytic subunit

1

5

High-throughput

0.536

High

644717

VPS52
Vacuolar protein sorting-associated protein 52 homolog

1

2

High-throughput

0.536

High

644719

PIGB
GPI mannosyltransferase 3

1

3

High-throughput

0.536

High

216045

NRDC
Nardilysin

1

0

High-throughput

0.513

High

644711

SGMR2
Sigma intracellular receptor 2

1

0

High-throughput

0.513

High

644712

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

3

High-throughput

0.489

High

644713

DCA10
DDB1- and CUL4-associated factor 10

1

3

High-throughput

0.489

High

644715

DUS29
Dual specificity phosphatase 29

1

1

High-throughput

0.489

High

644720

RSPRY
RING finger and SPRY domain-containing protein 1

1

1

High-throughput

0.489

High

644724

REEP4
Receptor expression-enhancing protein 4

1

4

High-throughput

0.489

High

644725

MITOS
Mitochondrial potassium channel ATP-binding subunit

1

6

High-throughput

0.489

High

644709

PDE4C
3',5'-cyclic-AMP phosphodiesterase 4C

2

0

High-throughput

0.316

High

403475

AT5G1
ATP synthase F(0) complex subunit C1, mitochondrial

1

0

High-throughput

0.279

Low

644706

SC11A
Signal peptidase complex catalytic subunit SEC11A

1

0

High-throughput

0.279

Low

644726

RMND1
Required for meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.279

Low

644729

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.279

Low

644707

RAE1L
mRNA export factor RAE1

1

0

Small-scale

0.261

Low


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Last updated: 15 Jul 2024