Protein: C1S
Complement C1s subcomponent (EC 3.4.21.42) (C1 esterase) (Complement component 1 subcomponent s) [Cleaved into: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain]

Gene: C1S
Organism: Homo sapiens
Interactions: 15
UniProt ID: P09871

Gene Ontology (top 5):
GO:0004252 - serine-type endopeptidase activity
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006508 - proteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

341158

C1R
Complement C1r subcomponent

7

16

Small-scale

0.964

High

416128

CO2
Complement C2

2

16

Small-scale

0.778

High

455001

C1S
Complement C1s subcomponent

2

15

Small-scale

0.778

High

397678

IC1
Plasma protease C1 inhibitor

2

20

Small-scale

0.737

High

455002

CO4A
Complement C4-A

1

7

Small-scale

0.724

High

455003

CO4B
Complement C4-B

1

7

Small-scale

0.647

High

455005

CCDC6
Coiled-coil domain-containing protein 6

2

4

High-throughput

0.574

High

455004

PKNX1
Homeobox protein PKNOX1

1

1

High-throughput

0.494

High

362450

C1QA
Complement C1q subcomponent subunit A

1

5

Small-scale

0.479

High

362731

FINC
Fibronectin

1

7

Small-scale

0.479

High

216653

CREB3
Cyclic AMP-responsive element-binding protein 3

1

1

High-throughput

0.470

High

455007

VKOR1
Vitamin K epoxide reductase complex subunit 1

1

4

Small-scale

0.439

High

455006

PP4R1
Serine/threonine-protein phosphatase 4 regulatory subunit 1

2

0

High-throughput

0.328

High

455008

REEP4
Receptor expression-enhancing protein 4

2

0

High-throughput

0.316

High


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Last updated: 15 Jul 2024