Protein: CDKL5
Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)

Gene: CDKL5
Organism: Homo sapiens
Interactions: 33
UniProt ID: O76039

Gene Ontology (top 5):
GO:0001764 - neuron migration
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

282289

MACF1
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5

2

14

High-throughput

0.789

High

282263

CDKL5
Cyclin-dependent kinase-like 5

2

19

Small-scale

0.768

High

282277

KGP2
cGMP-dependent protein kinase 2

1

13

High-throughput

0.665

High

282272

MLH1
DNA mismatch repair protein Mlh1

3

0

High-throughput

0.639

High

282279

CDC37
Hsp90 co-chaperone Cdc37

1

10

High-throughput

0.618

High

282264

ABL1
Tyrosine-protein kinase ABL1

1

19

High-throughput

0.618

High

282266

FYN
Tyrosine-protein kinase Fyn

1

18

High-throughput

0.618

High

224737

DHX16
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

2

5

High-throughput

0.611

High

282285

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

2

6

High-throughput

0.611

High

282290

KLH20
Kelch-like protein 20

2

2

High-throughput

0.611

High

282273

SPB8
Serpin B8

3

2

High-throughput

0.604

High

282281

RABL6
Rab-like protein 6

2

0

High-throughput

0.585

High

282274

MECP2
Methyl-CpG-binding protein 2

1

5

Small-scale

0.561

High

282265

RASK
GTPase KRas

1

5

High-throughput

0.553

High

282278

SKI2
Superkiller complex protein 2

1

7

High-throughput

0.541

High

282291

HDGR3
Hepatoma-derived growth factor-related protein 3

1

5

High-throughput

0.536

High

282287

SPTN4
Spectrin beta chain, non-erythrocytic 4

1

11

High-throughput

0.494

High

282292

TACC3
Transforming acidic coiled-coil-containing protein 3

1

14

High-throughput

0.494

High

282270

PTX3
Pentraxin-related protein PTX3

1

2

High-throughput

0.489

High

282267

LAMP1
Lysosome-associated membrane glycoprotein 1

1

1

High-throughput

0.479

High

282268

CADH1
Cadherin-1

1

4

High-throughput

0.479

High

282269

MGMT
Methylated-DNA--protein-cysteine methyltransferase

1

2

Small-scale

0.479

High

282271

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

20

High-throughput

0.479

High

282275

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.479

High

282282

UBAP2
Ubiquitin-associated protein 2

1

6

High-throughput

0.479

High

282283

HDGR2
Hepatoma-derived growth factor-related protein 2

1

3

High-throughput

0.479

High

282286

SNX27
Sorting nexin-27

1

11

High-throughput

0.479

High

282288

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

282276

GOGA2
Golgin subfamily A member 2

1

20

High-throughput

0.470

High

282280

AR13B
ADP-ribosylation factor-like protein 13B

1

3

High-throughput

0.437

High

282293

SAR1B
Small COPII coat GTPase SAR1B

1

4

High-throughput

0.437

High

282284

GPAM1
GPALPP motifs-containing protein 1

2

0

High-throughput

0.318

High


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Last updated: 15 Jul 2024