Protein: ARBK2
G protein-coupled receptor kinase 3 (EC 2.7.11.15) (Beta-adrenergic receptor kinase 2) (Beta-ARK-2)

Gene: ARBK2, GRK3
Organism: Homo sapiens
Interactions: 13
UniProt ID: P35626

Gene Ontology (top 5):
GO:0001664 - G protein-coupled receptor binding
GO:0002029 - desensitization of G protein-coupled receptor signaling pathway
GO:0004672 - protein kinase activity
GO:0004703 - G protein-coupled receptor kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

626628

ARBK1
Beta-adrenergic receptor kinase 1

3

16

High-throughput

0.861

High

428943

ADRB2
Beta-2 adrenergic receptor

1

10

Small-scale

0.647

High

226686

PRKN
E3 ubiquitin-protein ligase parkin

1

14

High-throughput

0.618

High

384389

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.618

High

726557

CCR4
C-C chemokine receptor type 4

1

12

Small-scale

0.618

High

726558

CXCR4
C-X-C chemokine receptor type 4

1

12

Small-scale

0.618

High

726563

GIT1
ARF GTPase-activating protein GIT1

1

10

Small-scale

0.618

High

388266

HSPB1
Heat shock protein beta-1

1

8

High-throughput

0.541

High

726562

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

14

Small-scale

0.501

High

726559

FOXO1
Forkhead box protein O1

1

10

High-throughput

0.479

High

726560

PTC1
Protein patched homolog 1

1

1

Small-scale

0.479

High

559000

H15
Histone H1.5

1

5

High-throughput

0.470

High

726561

TX101
Testis-expressed protein 101

1

0

High-throughput

0.426

High


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Last updated: 15 Jul 2024