Protein: THOP1
Thimet oligopeptidase (EC 3.4.24.15) (Endopeptidase 24.15) (MP78)

Gene: THOP1
Organism: Homo sapiens
Interactions: 45
UniProt ID: P52888

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0004222 - metalloendopeptidase activity
GO:0005758 - mitochondrial intermembrane space
GO:0005829 - cytosol
GO:0006508 - proteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

313971

PPN
Papilin

2

0

High-throughput

0.602

High

857009

OPTN
Optineurin

2

2

High-throughput

0.601

High

307515

EPN2
Epsin-2

2

0

High-throughput

0.580

High

857012

MPH6
M-phase phosphoprotein 6

2

0

High-throughput

0.551

High

856991

TTC3
E3 ubiquitin-protein ligase TTC3

1

1

High-throughput

0.541

High

857001

STK11
Serine/threonine-protein kinase STK11

1

0

High-throughput

0.518

High

857017

EXOS3
Exosome complex component RRP40

1

0

High-throughput

0.513

High

499641

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.493

High

857010

XAGE2
X antigen family member 2

1

1

High-throughput

0.489

High

856996

TRAF2
TNF receptor-associated factor 2

1

2

High-throughput

0.481

High

226938

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

438019

HS90B
Heat shock protein HSP 90-beta

1

1

High-throughput

0.479

High

650745

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

856992

HDAC4
Histone deacetylase 4

1

1

High-throughput

0.479

High

856994

EXOSX
Exosome complex component 10

1

1

High-throughput

0.479

High

856995

EXOS9
Exosome complex component RRP45

1

3

High-throughput

0.479

High

856997

CUL3
Cullin-3

1

2

High-throughput

0.479

High

856999

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

1

High-throughput

0.479

High

857000

EXOS7
Exosome complex component RRP42

1

3

High-throughput

0.479

High

857002

EXOS6
Exosome complex component MTR3

1

5

High-throughput

0.479

High

857008

EXOS8
Exosome complex component RRP43

1

3

High-throughput

0.479

High

857015

EXOS4
Exosome complex component RRP41

1

4

High-throughput

0.479

High

857016

EXOS5
Exosome complex component RRP46

1

4

High-throughput

0.479

High

857021

EXOS1
Exosome complex component CSL4

1

1

High-throughput

0.479

High

237181

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

0

High-throughput

0.458

High

856993

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

856998

EXOS2
Exosome complex component RRP4

1

0

High-throughput

0.458

High

857004

GGYF2
GRB10-interacting GYF protein 2

1

0

High-throughput

0.458

High

857006

DI3L1
DIS3-like exonuclease 1

1

0

High-throughput

0.458

High

857014

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

857003

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

552302

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

720037

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

857005

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

857011

DB118
Defensin beta 118

1

0

High-throughput

0.279

Low

857019

PALS2
Protein PALS2

1

0

High-throughput

0.251

Low

329526

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

338169

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.249

Low

384541

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

569442

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.249

Low

786914

MTREX
Exosome RNA helicase MTR4

1

0

High-throughput

0.249

Low

857007

TP4A1
Protein tyrosine phosphatase type IVA 1

1

0

High-throughput

0.249

Low

857018

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.249

Low

857020

TRI33
E3 ubiquitin-protein ligase TRIM33

1

0

High-throughput

0.249

Low

857013

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024