HitPredict - High confidence protein-protein interactions

Protein: M4K1
Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic progenitor kinase) (HPK) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1)

Gene: M4K1, Map4k1
Organism: Mus musculus
Interactions: 5
UniProt ID: P70218

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0006468 - protein phosphorylation
GO:0007254 - JNK cascade
GO:0008283 - cell population proliferation

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
999942	BLNK B-cell linker protein	2	17	Small-scale	0.576	High
999940	LCP2 Lymphocyte cytosolic protein 2	2	10	Small-scale	0.521	High
313430	GRAP2 GRB2-related adaptor protein 2	1	20	Small-scale	0.489	High
236819	LAT Linker for activation of T-cells family member 1	1	1	High-throughput	0.445	High
999941	FACD2 Fanconi anemia group D2 protein homolog	1	5	High-throughput	0.437	High

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Last updated: 11Aug2025