Protein: LAT
Linker for activation of T-cells family member 1 (36 kDa phosphotyrosine adapter protein) (pp36) (p36-38)

Gene: LAT
Organism: Mus musculus
Interactions: 60
UniProt ID: O54957

Gene Ontology (top 5):
GO:0001772 - immunological synapse
GO:0002250 - adaptive immune response
GO:0002260 - lymphocyte homeostasis
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

236831

GRB2
Growth factor receptor-bound protein 2

3

9

Small-scale

0.624

High

236836

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

3

2

Small-scale

0.624

High

236832

LCP2
Lymphocyte cytosolic protein 2

2

1

Small-scale

0.571

High

236827

CBLB
E3 ubiquitin-protein ligase CBL-B

2

2

High-throughput

0.552

High

236843

THMS1
Protein THEMIS

2

1

Small-scale

0.552

High

236828

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

0

High-throughput

0.458

High

236853

FOXP3
Forkhead box protein P3

1

0

High-throughput

0.458

High

236861

STK11
Serine/threonine-protein kinase STK11

1

0

Small-scale

0.458

High

236806

CBL
E3 ubiquitin-protein ligase CBL

1

2

High-throughput

0.445

High

236808

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

3

High-throughput

0.445

High

236809

VAV
Proto-oncogene vav

1

6

High-throughput

0.445

High

236812

FYN
Tyrosine-protein kinase Fyn

1

4

High-throughput

0.445

High

236814

STAT3
Signal transducer and activator of transcription 3

1

1

High-throughput

0.445

High

236819

M4K1
Mitogen-activated protein kinase kinase kinase kinase 1

1

1

High-throughput

0.445

High

236823

ITK
Tyrosine-protein kinase ITK/TSK

1

4

High-throughput

0.445

High

236834

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

1

High-throughput

0.445

High

236850

ARHG6
Rho guanine nucleotide exchange factor 6

1

2

High-throughput

0.445

High

236820

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

1

Small-scale

0.437

High

236807

TLN1
Talin-1

1

0

High-throughput

0.426

High

236822

LY9
T-lymphocyte surface antigen Ly-9

1

0

High-throughput

0.426

High

236826

STING
Stimulator of interferon genes protein

1

0

High-throughput

0.426

High

236837

SOS1
Son of sevenless homolog 1

1

0

High-throughput

0.426

High

236838

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.426

High

236841

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.426

High

236852

TADBP
TAR DNA-binding protein 43

1

0

High-throughput

0.426

High

236859

SHIP1
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

1

0

High-throughput

0.426

High

236803

ENPL
Endoplasmin

1

1

High-throughput

0.407

High

236813

STAT1
Signal transducer and activator of transcription 1

1

1

High-throughput

0.407

High

236818

IMB1
Importin subunit beta-1

1

1

High-throughput

0.407

High

236824

3BP2
SH3 domain-binding protein 2

1

1

High-throughput

0.407

High

236830

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

1

4

High-throughput

0.407

High

236833

VDAC3
Non-selective voltage-gated ion channel VDAC3

1

1

High-throughput

0.407

High

236840

ECM29
Proteasome adapter and scaffold protein ECM29

1

1

High-throughput

0.407

High

236845

DOC10
Dedicator of cytokinesis protein 10

1

1

High-throughput

0.407

High

236847

DOCK2
Dedicator of cytokinesis protein 2

1

1

High-throughput

0.407

High

236856

GRAP
GRB2-related adapter protein

1

9

High-throughput

0.407

High

236858

XPO2
Exportin-2

1

1

High-throughput

0.407

High

236354

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.232

Low

236804

GPX1
Glutathione peroxidase 1

1

0

High-throughput

0.232

Low

236805

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.232

Low

236810

TAP2
Antigen peptide transporter 2

1

0

High-throughput

0.232

Low

236811

DYN2
Dynamin-2

1

0

High-throughput

0.232

Low

236815

MCM5
DNA replication licensing factor MCM5

1

0

High-throughput

0.232

Low

236816

DNJA1
DnaJ homolog subfamily A member 1

1

0

High-throughput

0.232

Low

236817

1433T
14-3-3 protein theta

1

0

High-throughput

0.232

Low

236821

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

1

0

High-throughput

0.232

Low

236825

NSUN2
RNA cytosine C(5)-methyltransferase NSUN2

1

0

High-throughput

0.232

Low

236829

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

0

High-throughput

0.232

Low

236835

PDCD4
Programmed cell death protein 4

1

0

High-throughput

0.232

Low

236839

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.232

Low

236842

GVIN1
Interferon-induced very large GTPase 1

1

0

High-throughput

0.232

Low

236844

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

0

High-throughput

0.232

Low

236846

RASL3
RAS protein activator like-3

1

0

High-throughput

0.232

Low

236848

WIPF1
WAS/WASL-interacting protein family member 1

1

0

High-throughput

0.232

Low

236849

CND1
Condensin complex subunit 1

1

0

High-throughput

0.232

Low

236851

SF3B4
Splicing factor 3B subunit 4

1

0

High-throughput

0.232

Low

236854

PSIP1
PC4 and SFRS1-interacting protein

1

0

High-throughput

0.232

Low

236855

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

0

High-throughput

0.232

Low

236857

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.232

Low

236860

PR40A
Pre-mRNA-processing factor 40 homolog A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025