Protein: SOCS5
Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2 protein 6) (CIS-6) (Cytokine-inducible SH2-containing protein 5)

Gene: SOCS5
Organism: Homo sapiens
Interactions: 21
UniProt ID: O75159

Gene Ontology (top 5):
GO:0005154 - epidermal growth factor receptor binding
GO:0005829 - cytosol
GO:0005942 - phosphatidylinositol 3-kinase complex
GO:0007173 - epidermal growth factor receptor signaling pathway
GO:0007175 - negative regulation of epidermal growth factor-activated receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

256856

CUL5
Cullin-5

2

20

High-throughput

0.811

High

256842

EGFR
Epidermal growth factor receptor

2

20

Small-scale

0.789

High

256854

ELOC
Elongin-C

2

10

Small-scale

0.743

High

256847

KIT
Mast/stem cell growth factor receptor Kit

1

20

High-throughput

0.692

High

256843

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.647

High

256849

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.647

High

256853

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.647

High

256845

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.619

High

256851

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

16

Small-scale

0.618

High

256844

A4
Amyloid-beta precursor protein

2

8

High-throughput

0.602

High

256850

IL4RA
Interleukin-4 receptor subunit alpha

1

20

Small-scale

0.561

High

256861

ALK
ALK tyrosine kinase receptor

1

20

Small-scale

0.553

High

256852

CASP3
Caspase-3

1

3

High-throughput

0.541

High

256858

DCNL1
DCN1-like protein 1

1

4

High-throughput

0.536

High

256860

RBX2
RING-box protein 2

1

9

High-throughput

0.536

High

256846

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

5

High-throughput

0.501

High

256855

ELOB
Elongin-B

1

10

Small-scale

0.479

High

256862

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.458

High

256848

CO6A1

1

1

Small-scale

0.437

High

256859

Q9BPW0
Serine/threonine-protein phosphatase

1

3

High-throughput

0.437

High

256857

LFG3
Protein lifeguard 3

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024