Protein: OBSCN
Obscurin (EC 2.7.11.1) (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK)

Gene: OBSCN
Organism: Homo sapiens
Interactions: 58
UniProt ID: Q5VST9

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1137771

TITIN
Titin

5

17

Small-scale

0.944

High

556706

ANK1
Ankyrin-1

4

7

Small-scale

0.908

High

508055

FGFR1
Fibroblast growth factor receptor 1

2

12

High-throughput

0.737

High

279313

DNJB5
DnaJ homolog subfamily B member 5

1

7

High-throughput

0.698

High

1048098

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

15

High-throughput

0.691

High

1137765

MLKL
Mixed lineage kinase domain-like protein

1

2

High-throughput

0.691

High

1137769

BRSK1
Serine/threonine-protein kinase BRSK1

1

13

High-throughput

0.691

High

1137777

SHLB2
Endophilin-B2

1

1

High-throughput

0.691

High

749581

BRCA1
Breast cancer type 1 susceptibility protein

1

8

High-throughput

0.621

High

965118

ANK2
Ankyrin-2

1

7

Small-scale

0.618

High

1137762

WDR82
WD repeat-containing protein 82

1

12

High-throughput

0.553

High

1137768

POC1B
POC1 centriolar protein homolog B

1

8

High-throughput

0.553

High

451689

CLCB
Clathrin light chain B

1

2

High-throughput

0.536

High

517302

PCNA
Proliferating cell nuclear antigen

1

2

High-throughput

0.536

High

530902

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

1

High-throughput

0.536

High

651419

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.536

High

792714

EAA1
Excitatory amino acid transporter 1

1

1

High-throughput

0.536

High

933476

TBA4A
Tubulin alpha-4A chain

1

8

High-throughput

0.536

High

1044609

FHL3
Four and a half LIM domains protein 3

1

12

High-throughput

0.536

High

1128093

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

1

High-throughput

0.536

High

1137761

LYPD4
Ly6/PLAUR domain-containing protein 4

1

1

High-throughput

0.536

High

1137763

TBA1A
Tubulin alpha-1A chain

1

7

High-throughput

0.536

High

1137775

DIDO1
Death-inducer obliterator 1

1

12

High-throughput

0.536

High

382022

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

1

High-throughput

0.515

High

1034072

TCOF
Treacle protein

1

13

High-throughput

0.515

High

1087182

H2B2E
Histone H2B type 2-E

1

12

High-throughput

0.515

High

1137772

ESR2
Estrogen receptor beta

1

10

High-throughput

0.514

High

868542

ATX1
Ataxin-1

1

0

High-throughput

0.513

High

1137764

MON2
Protein MON2 homolog

1

0

High-throughput

0.513

High

1137773

CDCA5
Sororin

1

0

High-throughput

0.513

High

1137778

VPS18
Vacuolar protein sorting-associated protein 18 homolog

1

0

High-throughput

0.513

High

1137779

GGT7
Glutathione hydrolase 7

1

0

High-throughput

0.513

High

925900

AP2B1
AP-2 complex subunit beta

1

3

High-throughput

0.501

High

502199

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.479

High

806335

RL21
Large ribosomal subunit protein eL21

1

1

High-throughput

0.479

High

829016

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

5

High-throughput

0.479

High

870826

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

1

High-throughput

0.479

High

913570

RL7A
Large ribosomal subunit protein eL8

1

2

High-throughput

0.479

High

1085769

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

1137757

RN123
E3 ubiquitin-protein ligase RNF123

1

10

High-throughput

0.479

High

1137758

DCA15
DDB1- and CUL4-associated factor 15

1

1

High-throughput

0.479

High

1137759

RNF43
E3 ubiquitin-protein ligase RNF43

1

3

High-throughput

0.479

High

1137766

KCTD6
BTB/POZ domain-containing protein KCTD6

1

4

Small-scale

0.479

High

1137767

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

1137770

NUDC2
NudC domain-containing protein 2

1

2

High-throughput

0.479

High

666399

3MG
DNA-3-methyladenine glycosylase

1

0

Small-scale

0.458

High

1137780

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.458

High

1043046

CUL4A
Cullin-4A

1

14

High-throughput

0.437

High

347018

MYC
Myc proto-oncogene protein

1

11

High-throughput

0.407

High

1137756

BTBD8
BTB/POZ domain-containing protein 8

1

10

High-throughput

0.407

High

351535

ANF
Natriuretic peptides A

1

0

High-throughput

0.279

Low

396945

HMGN1
Non-histone chromosomal protein HMG-14

1

0

High-throughput

0.279

Low

448693

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.279

Low

977892

HSF2
Heat shock factor protein 2

1

0

High-throughput

0.279

Low

1074603

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.279

Low

1137760

HEAT6
HEAT repeat-containing protein 6

1

0

High-throughput

0.279

Low

1137776

ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2

1

0

High-throughput

0.249

Low

1137774

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024