Protein: RGS14
Regulator of G-protein signaling 14 (RGS14) (RAP1/RAP2-interacting protein) (RPIP1)

Gene: RGS14
Organism: Mus musculus
Interactions: 222
UniProt ID: P97492

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0000922 - spindle pole
GO:0001965 - G-protein alpha-subunit binding
GO:0005092 - GDP-dissociation inhibitor activity
GO:0005096 - GTPase activator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

548943

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

4

High-throughput

0.724

High

267267

CSKP
Peripheral plasma membrane protein CASK

1

8

High-throughput

0.618

High

617638

GNAO
Guanine nucleotide-binding protein G(o) subunit alpha

1

20

High-throughput

0.618

High

632510

KPCA
Protein kinase C alpha type

1

4

High-throughput

0.618

High

704210

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

4

High-throughput

0.618

High

1021550

RGS14
Regulator of G-protein signaling 14

1

6

High-throughput

0.618

High

1021559

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

3

High-throughput

0.618

High

1021565

UN13A
Protein unc-13 homolog A

1

5

High-throughput

0.618

High

1021581

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.618

High

1021582

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

4

High-throughput

0.618

High

1021599

COR2B
Coronin-2B

1

4

High-throughput

0.618

High

1021632

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

4

High-throughput

0.618

High

1021671

ARC1A
Actin-related protein 2/3 complex subunit 1A

1

2

High-throughput

0.618

High

107104

FARP1
FERM, ARHGEF and pleckstrin domain-containing protein 1

1

0

High-throughput

0.586

High

953798

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.586

High

1021552

MARK2
Serine/threonine-protein kinase MARK2

1

0

High-throughput

0.586

High

1021665

SRCN1
SRC kinase signaling inhibitor 1

2

2

High-throughput

0.571

High

770632

RAB18
Ras-related protein Rab-18

1

3

High-throughput

0.553

High

925772

RAB2A
Ras-related protein Rab-2A

1

2

High-throughput

0.553

High

1021607

COR2A
Coronin-2A

1

3

High-throughput

0.553

High

1021675

COR1C
Coronin-1C

1

4

High-throughput

0.553

High

981393

RAB1A
Ras-related protein Rab-1A

1

0

High-throughput

0.517

High

92675

SHAN1
SH3 and multiple ankyrin repeat domains protein 1

1

8

High-throughput

0.479

High

104512

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

2

High-throughput

0.479

High

108988

RFIP2
Rab11 family-interacting protein 2

1

11

High-throughput

0.479

High

109259

ANK3
Ankyrin-3

1

5

High-throughput

0.479

High

205365

SYT3
Synaptotagmin-3

1

3

High-throughput

0.479

High

312897

BSN
Protein bassoon

1

3

High-throughput

0.479

High

559567

GELS
Gelsolin

1

1

High-throughput

0.479

High

570739

RL7
Large ribosomal subunit protein uL30

1

1

High-throughput

0.479

High

580359

CADH2
Cadherin-2

1

1

High-throughput

0.479

High

619280

NFH
Neurofilament heavy polypeptide

1

1

High-throughput

0.479

High

636001

TPM3
Tropomyosin alpha-3 chain

1

2

High-throughput

0.479

High

655042

CXA1
Gap junction alpha-1 protein

1

2

High-throughput

0.479

High

704247

NP1L1
Nucleosome assembly protein 1-like 1

1

3

High-throughput

0.479

High

714571

NEDD8
Ubiquitin-like protein NEDD8

1

1

High-throughput

0.479

High

732013

GTR3
Solute carrier family 2, facilitated glucose transporter member 3

1

1

High-throughput

0.479

High

776902

CD81
CD81 antigen

1

1

High-throughput

0.479

High

846988

H14
Histone H1.4

1

4

High-throughput

0.479

High

855290

SYT1
Synaptotagmin-1

1

3

High-throughput

0.479

High

855309

SYT2
Synaptotagmin-2

1

3

High-throughput

0.479

High

858742

MYO1B
Unconventional myosin-Ib

1

4

High-throughput

0.479

High

893587

GBG4

1

2

High-throughput

0.479

High

946686

TPM1
Tropomyosin alpha-1 chain

1

2

High-throughput

0.479

High

958391

ARP2
Actin-related protein 2

1

1

High-throughput

0.479

High

968076

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

4

High-throughput

0.479

High

968499

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

5

High-throughput

0.479

High

997220

TBA4A
Tubulin alpha-4A chain

1

2

High-throughput

0.479

High

997241

TBA1A
Tubulin alpha-1A chain

1

2

High-throughput

0.479

High

1000425

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

4

High-throughput

0.479

High

1021394

MPRIP
Myosin phosphatase Rho-interacting protein

1

4

High-throughput

0.479

High

1021551

CTNB1
Catenin beta-1

1

6

High-throughput

0.479

High

1021554

PSD3
PH and SEC7 domain-containing protein 3

1

1

High-throughput

0.479

High

1021557

Q3UGX2
Spectrin beta chain

1

5

High-throughput

0.479

High

1021561

Q3URF1
Synaptopodin

1

1

High-throughput

0.479

High

1021562

LRRF1
Leucine-rich repeat flightless-interacting protein 1

1

1

High-throughput

0.479

High

1021563

Q3UZI0
Heterogeneous nuclear ribonucleoprotein Q

1

1

High-throughput

0.479

High

1021564

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

9

High-throughput

0.479

High

1021566

SRC8
Src substrate cortactin

1

1

High-throughput

0.479

High

1021568

MYH10
Myosin-10

1

2

High-throughput

0.479

High

1021569

NPM
Nucleophosmin

1

1

High-throughput

0.479

High

1021571

DLG4
Disks large homolog 4

1

3

High-throughput

0.479

High

1021572

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

6

High-throughput

0.479

High

1021574

Q68FG2
Spectrin beta chain

1

6

High-throughput

0.479

High

1021575

PKP4
Plakophilin-4

1

9

High-throughput

0.479

High

1021577

CSKI1
Caskin-1

1

6

High-throughput

0.479

High

1021579

DLGP3
Disks large-associated protein 3

1

3

High-throughput

0.479

High

1021580

ERC2
ERC protein 2

1

5

High-throughput

0.479

High

1021583

NEB2
Neurabin-2

1

13

High-throughput

0.479

High

1021585

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

2

High-throughput

0.479

High

1021586

NP1L4
Nucleosome assembly protein 1-like 4

1

3

High-throughput

0.479

High

1021587

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

1

High-throughput

0.479

High

1021588

TBB2A
Tubulin beta-2A chain

1

4

High-throughput

0.479

High

1021589

Q7TN74
Neurabin-1

1

13

High-throughput

0.479

High

1021590

ACTN1
Alpha-actinin-1

1

5

High-throughput

0.479

High

1021591

GBG5

1

2

High-throughput

0.479

High

1021595

MYPT2
Protein phosphatase 1 regulatory subunit 12B

1

8

High-throughput

0.479

High

1021596

SYAC
Alanine--tRNA ligase, cytoplasmic

1

5

High-throughput

0.479

High

1021602

ANS1B
Ankyrin repeat and sterile alpha motif domain-containing protein 1B

1

7

High-throughput

0.479

High

1021604

BAIP2
BAR/IMD domain-containing adapter protein 2

1

1

High-throughput

0.479

High

1021610

ANK2
Ankyrin-2

1

5

High-throughput

0.479

High

1021614

ABLM1
Actin-binding LIM protein 1

1

2

High-throughput

0.479

High

1021617

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

1

High-throughput

0.479

High

1021620

ACTY
Beta-centractin

1

1

High-throughput

0.479

High

1021622

MYH9
Myosin-9

1

2

High-throughput

0.479

High

1021623

MICA1
[F-actin]-monooxygenase MICAL1

1

4

High-throughput

0.479

High

1021629

DLG2
Disks large homolog 2

1

3

High-throughput

0.479

High

1021630

BASP1
Brain acid soluble protein 1

1

2

High-throughput

0.479

High

1021636

ARP3
Actin-related protein 3

1

1

High-throughput

0.479

High

1021641

TBB2B
Tubulin beta-2B chain

1

4

High-throughput

0.479

High

1021646

DYL2
Dynein light chain 2, cytoplasmic

1

1

High-throughput

0.479

High

1021647

RUFY3
Protein RUFY3

1

1

Small-scale

0.479

High

1021648

DLGP1
Disks large-associated protein 1

1

3

High-throughput

0.479

High

1021649

TBB4A
Tubulin beta-4A chain

1

4

High-throughput

0.479

High

1021653

GBG12

1

2

High-throughput

0.479

High

1021654

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

7

High-throughput

0.479

High

1021657

IPO7
Importin-7

1

1

High-throughput

0.479

High

1021659

T22D4
TSC22 domain family protein 4

1

2

High-throughput

0.479

High

1021661

TMOD2
Tropomodulin-2

1

1

High-throughput

0.479

High

1021666

DREB
Drebrin

1

3

High-throughput

0.479

High

1021667

ADDG
Gamma-adducin

1

2

High-throughput

0.479

High

1021668

ADDB
Beta-adducin

1

4

High-throughput

0.479

High

1021669

PCLO
Protein piccolo

1

11

High-throughput

0.479

High

1021670

SYT7
Synaptotagmin-7

1

3

High-throughput

0.479

High

1021672

TRIM3
Tripartite motif-containing protein 3

1

7

High-throughput

0.479

High

92787

ERIP6
Glutamate-rich protein 6

1

0

High-throughput

0.458

High

237401

PSB5
Proteasome subunit beta type-5

1

0

High-throughput

0.458

High

456910

ANXA2
Annexin A2

1

0

High-throughput

0.458

High

704257

ATX10
Ataxin-10

1

0

High-throughput

0.458

High

778144

RL18
Large ribosomal subunit protein eL18

1

0

High-throughput

0.458

High

867573

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.458

High

868920

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.458

High

902724

RL9
Large ribosomal subunit protein uL6

1

0

High-throughput

0.458

High

945989

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

0

High-throughput

0.458

High

948493

ARPC4
Actin-related protein 2/3 complex subunit 4

1

0

High-throughput

0.458

High

973013

RS18
Small ribosomal subunit protein uS13

1

0

High-throughput

0.458

High

973646

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.458

High

976066

KCAB2
Voltage-gated potassium channel subunit beta-2

1

0

High-throughput

0.458

High

977649

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.458

High

979391

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.458

High

983241

RS26
Small ribosomal subunit protein eS26

1

0

High-throughput

0.458

High

983368

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.458

High

985403

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

989421

DNJA1
DnaJ homolog subfamily A member 1

1

0

High-throughput

0.458

High

993064

IPKA
cAMP-dependent protein kinase inhibitor alpha

1

0

High-throughput

0.458

High

993090

ACTG
Actin, cytoplasmic 2

1

0

High-throughput

0.458

High

993965

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.458

High

995513

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.458

High

1021204

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.458

High

1021558

LIMC1
LIM and calponin homology domains-containing protein 1

1

0

High-throughput

0.458

High

1021578

Q6PCS8
Zinc finger and BTB domain containing 40

1

0

High-throughput

0.458

High

1021584

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

0

High-throughput

0.458

High

1021592

LRRC7
Leucine-rich repeat-containing protein 7

1

0

High-throughput

0.458

High

1021600

TB10B
TBC1 domain family member 10B

1

0

High-throughput

0.458

High

1021616

IP3KA
Inositol-trisphosphate 3-kinase A

1

0

High-throughput

0.458

High

1021621

Q8R5L1
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1021624

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

0

High-throughput

0.458

High

1021625

MLC1
Membrane protein MLC1

1

0

High-throughput

0.458

High

1021626

ACO11
Acyl-coenzyme A thioesterase 11

1

0

High-throughput

0.458

High

1021634

MYO5A
Unconventional myosin-Va

1

0

High-throughput

0.458

High

1021640

ARPC2
Actin-related protein 2/3 complex subunit 2

1

0

High-throughput

0.458

High

1021642

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1021645

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.458

High

1021652

ARP5L
Actin-related protein 2/3 complex subunit 5-like protein

1

0

High-throughput

0.458

High

1021655

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.458

High

1021662

KCJ10
ATP-sensitive inward rectifier potassium channel 10

1

0

High-throughput

0.458

High

1021663

BORG4
Cdc42 effector protein 4

1

0

High-throughput

0.458

High

1021674

LY6H
Lymphocyte antigen 6H

1

0

High-throughput

0.458

High

1021677

HOME1
Homer protein homolog 1

1

0

High-throughput

0.458

High

450390

CSF1
Macrophage colony-stimulating factor 1

1

1

Small-scale

0.445

High

86343

B9EKJ1
Spectrin alpha chain, non-erythrocytic 1

1

5

High-throughput

0.437

High

94720

E0CYM1
Filamin A interacting protein 1-like

1

6

High-throughput

0.437

High

97916

E9Q3M9
Capping protein inhibiting regulator of actin like

1

3

High-throughput

0.437

High

98321

E9QKZ2
Importin 9

1

2

High-throughput

0.437

High

98394

E9QPD7
Pyruvate carboxylase

1

1

High-throughput

0.437

High

98403

E9QPE7
Myosin-11

1

2

High-throughput

0.437

High

866571

CAZA1
F-actin-capping protein subunit alpha-1

1

1

High-throughput

0.437

High

866591

CAZA2
F-actin-capping protein subunit alpha-2

1

1

High-throughput

0.437

High

890790

TMOD1
Tropomodulin-1

1

1

High-throughput

0.437

High

946703

TPM2
Tropomyosin beta chain

1

2

High-throughput

0.437

High

997585

TBB4B
Tubulin beta-4B chain

1

4

High-throughput

0.437

High

1021555

ML12B
Myosin regulatory light chain 12B

1

2

High-throughput

0.437

High

1021556

HDHD2
Haloacid dehalogenase-like hydrolase domain-containing protein 2

1

2

High-throughput

0.437

High

1021560

Q3UPB2
Cytospin-B

1

3

High-throughput

0.437

High

1021567

MYL6
Myosin light polypeptide 6

1

2

High-throughput

0.437

High

1021570

MYL10
Myosin regulatory light chain 10

1

2

High-throughput

0.437

High

1021605

ABLM2
Actin-binding LIM protein 2

1

3

High-throughput

0.437

High

1021611

MYL6B
Myosin light chain 6B

1

2

High-throughput

0.437

High

1021613

LIN7A
Protein lin-7 homolog A

1

5

High-throughput

0.437

High

1021627

LRRF2
Leucine-rich repeat flightless-interacting protein 2

1

1

High-throughput

0.437

High

1021631

ASB9
Ankyrin repeat and SOCS box protein 9

1

5

High-throughput

0.437

High

1021633

ATD3A
ATPase family AAA domain-containing protein 3A

1

1

High-throughput

0.437

High

1021635

Q99JL6
Ribosomal protein

1

1

High-throughput

0.437

High

1021637

DHRS4
Dehydrogenase/reductase SDR family member 4

1

1

High-throughput

0.437

High

1021638

MYL9
Myosin regulatory light polypeptide 9

1

2

High-throughput

0.437

High

1021644

Q9CZ19
Myosin, light polypeptide 4

1

2

High-throughput

0.437

High

1021660

FLII
Protein flightless-1 homolog

1

2

High-throughput

0.437

High

1021664

MY18A
Unconventional myosin-XVIIIa

1

4

High-throughput

0.437

High

1021678

V9GX76
Unconventional myosin-VI

1

3

High-throughput

0.437

High

74090

PTPRB
Receptor-type tyrosine-protein phosphatase beta

1

0

High-throughput

0.249

Low

74684

B2RXT3
2-oxoglutarate dehydrogenase-like, mitochondrial

1

0

High-throughput

0.249

Low

94728

E0CYV0
Protein-L-isoaspartate O-methyltransferase

1

0

High-throughput

0.249

Low

97993

APOB
Apolipoprotein B-100

1

0

High-throughput

0.249

Low

104775

F7BGR7
RNA-binding protein 14

1

0

High-throughput

0.249

Low

109197

G5E846
Peripherin

1

0

High-throughput

0.249

Low

148113

THYG
Thyroglobulin

1

0

High-throughput

0.249

Low

236708

AKAP2
PALM2-AKAP2 fusion protein

1

0

High-throughput

0.249

Low

237229

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

0

High-throughput

0.249

Low

397826

ATP8
ATP synthase F(0) complex subunit 8

1

0

High-throughput

0.249

Low

852473

COF2
Cofilin-2

1

0

High-throughput

0.249

Low

866555

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

0

High-throughput

0.249

Low

912403

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

1

0

High-throughput

0.249

Low

968847

PRS4
26S proteasome regulatory subunit 4

1

0

High-throughput

0.249

Low

999759

IMB1
Importin subunit beta-1

1

0

High-throughput

0.249

Low

1000372

IDHG1
Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial

1

0

High-throughput

0.249

Low

1021269

G3BP2
Ras GTPase-activating protein-binding protein 2

1

0

High-throughput

0.249

Low

1021553

CALB2
Calretinin

1

0

High-throughput

0.249

Low

1021573

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.249

Low

1021576

SV2C
Synaptic vesicle glycoprotein 2C

1

0

High-throughput

0.249

Low

1021593

RN214
RING finger protein 214

1

0

High-throughput

0.249

Low

1021594

SH3L2
SH3 domain-binding glutamic acid-rich-like protein 2

1

0

High-throughput

0.249

Low

1021597

HPCL4
Hippocalcin-like protein 4

1

0

High-throughput

0.249

Low

1021598

Q8BH40
Syntaxin-7

1

0

High-throughput

0.249

Low

1021601

ELMO2
Engulfment and cell motility protein 2

1

0

High-throughput

0.249

Low

1021603

ZC21A
Zinc finger C2HC domain-containing protein 1A

1

0

High-throughput

0.249

Low

1021606

AOFB
Amine oxidase [flavin-containing] B

1

0

High-throughput

0.249

Low

1021608

Q8C1W8
NAD(P) transhydrogenase, mitochondrial

1

0

High-throughput

0.249

Low

1021609

CA198
Uncharacterized protein C1orf198 homolog

1

0

High-throughput

0.249

Low

1021612

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

0

High-throughput

0.249

Low

1021615

HIBCH
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial

1

0

High-throughput

0.249

Low

1021618

QCR9
Cytochrome b-c1 complex subunit 9

1

0

High-throughput

0.249

Low

1021619

CADM4
Cell adhesion molecule 4

1

0

High-throughput

0.249

Low

1021628

Q91XH6
Vesicle transport through interaction with t-SNAREs homolog 1B

1

0

High-throughput

0.249

Low

1021639

NDUA6
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6

1

0

High-throughput

0.249

Low

1021643

GAPR1
Golgi-associated plant pathogenesis-related protein 1

1

0

High-throughput

0.249

Low

1021650

GHC1
Mitochondrial glutamate carrier 1

1

0

High-throughput

0.249

Low

1021651

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

0

High-throughput

0.249

Low

1021656

ETHE1
Persulfide dioxygenase ETHE1, mitochondrial

1

0

High-throughput

0.249

Low

1021658

MMSA
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial

1

0

High-throughput

0.249

Low

1021673

PYGM
Glycogen phosphorylase, muscle form

1

0

High-throughput

0.249

Low

1021676

SUCA
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025