Protein: PBS2
MAP kinase kinase PBS2 (EC 2.7.12.2) (Polymyxin B resistance protein 2) (Suppressor of fluoride sensitivity 4)

Gene: PBS2
Organism: Saccharomyces cerevisiae S288C
Interactions: 82
UniProt ID: P08018

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0004596 - peptide alpha-N-acetyltransferase activity
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004708 - MAP kinase kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

434744

HOG1
Mitogen-activated protein kinase HOG1

9

20

Small-scale

0.972

High

434770

SSK2
MAP kinase kinase kinase SSK2

7

20

Small-scale

0.971

High

434735

STE11
Serine/threonine-protein kinase STE11

5

17

Small-scale

0.925

High

434749

PP2C1
Protein phosphatase 2C homolog 1

4

12

Small-scale

0.894

High

434738

SSK22
Serine/threonine-protein kinase SSK22

2

20

Small-scale

0.831

High

434772

ACT
Actin

2

7

High-throughput

0.754

High

434786

NBP2
NAP1-binding protein 2

6

1

Small-scale

0.738

High

434760

SHO1
High osmolarity signaling protein SHO1

10

0

Small-scale

0.725

High

434753

MSG5
Tyrosine-protein phosphatase MSG5

1

10

High-throughput

0.691

High

434771

NOP15
Ribosome biogenesis protein 15

1

12

High-throughput

0.691

High

434775

CDC14
Tyrosine-protein phosphatase CDC14

1

9

High-throughput

0.691

High

425567

KAPR
cAMP-dependent protein kinase regulatory subunit

1

15

High-throughput

0.647

High

434732

RAD53
Serine/threonine-protein kinase RAD53

1

19

High-throughput

0.647

High

434733

KCC2
Calcium/calmodulin-dependent protein kinase II

1

17

High-throughput

0.647

High

434767

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

19

High-throughput

0.647

High

434774

RHO4
GTP-binding protein RHO4

1

20

High-throughput

0.647

High

434725

SSB1
Ribosome-associated molecular chaperone SSB1

3

20

High-throughput

0.633

High

410050

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

2

High-throughput

0.618

High

434719

PBS2
MAP kinase kinase PBS2

1

20

Small-scale

0.618

High

434743

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

18

High-throughput

0.618

High

434745

MKK1
MAP kinase kinase MKK1/SSP32

1

19

Small-scale

0.618

High

434776

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

20

Small-scale

0.618

High

434777

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

12

High-throughput

0.618

High

434785

YRA1
RNA annealing protein YRA1

1

5

High-throughput

0.595

High

434742

XPO1
Exportin-1

1

14

High-throughput

0.536

High

434781

SSK1
Osmolarity two-component system protein SSK1

1

0

High-throughput

0.530

High

334407

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

7

High-throughput

0.515

High

434734

IF5A1
Eukaryotic translation initiation factor 5A-1

1

1

High-throughput

0.515

High

434737

NAP1
Nucleosome assembly protein

1

4

High-throughput

0.515

High

434750

GLYC
Serine hydroxymethyltransferase, cytosolic

1

3

High-throughput

0.515

High

434768

BIOA
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

1

0

High-throughput

0.513

High

389668

CDC25
Cell division control protein 25

1

4

High-throughput

0.501

High

434780

CYK2
Cytokinesis protein 2

1

6

High-throughput

0.501

High

341885

ATPB
ATP synthase subunit beta, mitochondrial

1

12

High-throughput

0.500

High

342619

ENO1
Enolase 1

1

5

High-throughput

0.500

High

389196

HXKA
Hexokinase-1

1

3

High-throughput

0.500

High

410860

PDC1
Pyruvate decarboxylase isozyme 1

1

2

High-throughput

0.500

High

424969

DHE4
NADP-specific glutamate dehydrogenase 1

1

1

High-throughput

0.500

High

434720

HSP73
Heat shock protein SSA3

1

20

High-throughput

0.500

High

434730

BIP
Endoplasmic reticulum chaperone BiP

1

20

High-throughput

0.500

High

434731

HSP60
Heat shock protein 60, mitochondrial

1

18

High-throughput

0.500

High

434747

HSP79
Heat shock protein homolog SSE2

1

20

High-throughput

0.500

High

434754

ARO9
Aromatic amino acid aminotransferase 2

1

2

High-throughput

0.500

High

434756

SAHH
Adenosylhomocysteinase

1

5

High-throughput

0.500

High

434729

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

2

High-throughput

0.489

High

434763

MAM33
Mitochondrial acidic protein MAM33

1

2

High-throughput

0.489

High

434748

RGT1
Glucose transport transcription regulator RGT1

1

0

Small-scale

0.480

High

434751

OLA1
Obg-like ATPase 1

1

1

High-throughput

0.479

High

434752

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

20

High-throughput

0.479

High

434755

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.479

High

434759

ARB1
ABC transporter ATP-binding protein ARB1

1

2

High-throughput

0.479

High

434787

RIO1
Serine/threonine-protein kinase RIO1

1

2

High-throughput

0.479

High

434758

SNU13
13 kDa ribonucleoprotein-associated protein

1

3

High-throughput

0.470

High

434769

ZPR1
Zinc finger chaperone ZPR1

1

0

High-throughput

0.458

High

434782

YD073
UPF0592 protein YDL073W

1

0

Small-scale

0.458

High

434783

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

434766

BBC1
Myosin tail region-interacting protein MTI1

1

6

High-throughput

0.457

High

434788

SMT3
Ubiquitin-like protein SMT3

1

3

High-throughput

0.457

High

434778

MYO5
Myosin-5

1

20

High-throughput

0.457

High

378259

LEU3
3-isopropylmalate dehydrogenase

1

5

High-throughput

0.457

High

397565

OTC
Ornithine carbamoyltransferase

1

9

High-throughput

0.457

High

434721

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

2

High-throughput

0.457

High

434726

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.457

High

434722

HSP77
Import motor subunit, mitochondrial

1

20

High-throughput

0.445

High

434723

HSP71
Heat shock protein SSA1

1

20

High-throughput

0.445

High

434724

HSP72
Heat shock protein SSA2

1

20

High-throughput

0.445

High

434727

VATB
V-type proton ATPase subunit B

1

13

High-throughput

0.445

High

434746

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

434757

HSP7E
Heat shock protein SSC3, mitochondrial

1

20

High-throughput

0.445

High

434761

SSB2
Ribosome-associated molecular chaperone SSB2

1

20

High-throughput

0.445

High

434762

6P21
6-phosphofructo-2-kinase 1

1

4

High-throughput

0.445

High

434728

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.437

High

434740

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.437

High

434784

AP3D
AP-3 complex subunit delta

1

4

High-throughput

0.437

High

434741

BEM1
Bud emergence protein 1

1

20

Small-scale

0.408

High

434736

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.279

Low

434764

FET4
Low-affinity Fe(2+) transport protein

1

0

High-throughput

0.279

Low

434765

NET1
Nucleolar protein NET1

1

0

High-throughput

0.279

Low

434739

YCQ6
Uncharacterized protein YCR016W

1

0

High-throughput

0.261

Low

434773

PEX13
Peroxisomal membrane protein PEX13

1

0

High-throughput

0.261

Low

434779

SOV1
Protein SOV1, mitochondrial

1

0

High-throughput

0.261

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024