Protein: PACN1
Protein kinase C and casein kinase substrate in neurons protein 1 (Syndapin-1)

Gene: PACN1, PACSIN1
Organism: Homo sapiens
Interactions: 82
UniProt ID: Q9BY11

Gene Ontology (top 5):
GO:0005543 - phospholipid binding
GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1417662

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

11

15

Small-scale

0.981

High

1417659

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

9

16

Small-scale

0.974

High

1417658

RAI14
Ankycorbin

3

11

High-throughput

0.855

High

1417650

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

3

16

Small-scale

0.834

High

1353478

ANR24
Ankyrin repeat domain-containing protein 24

2

12

High-throughput

0.785

High

271174

COBL
Protein cordon-bleu

5

6

High-throughput

0.717

High

258394

GAS7
Growth arrest-specific protein 7

1

18

High-throughput

0.698

High

1250770

MPRIP
Myosin phosphatase Rho-interacting protein

3

12

High-throughput

0.662

High

1417651

TARA
TRIO and F-actin-binding protein

3

9

High-throughput

0.662

High

1229256

RHG17
Rho GTPase-activating protein 17

3

19

Small-scale

0.658

High

1200466

COBL1
Cordon-bleu protein-like 1

5

13

High-throughput

0.655

High

843945

HD
Huntingtin

3

5

Small-scale

0.654

High

133687

WASL
Actin nucleation-promoting factor WASL

3

20

Small-scale

0.641

High

1394602

ITCH
E3 ubiquitin-protein ligase Itchy homolog

2

5

Small-scale

0.639

High

1417660

ASAP1
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1

1

10

Small-scale

0.618

High

869519

TNFL6
Tumor necrosis factor ligand superfamily member 6

2

9

Small-scale

0.612

High

1050712

DYN1
Dynamin-1

2

20

Small-scale

0.611

High

1336683

EHBP1
EH domain-binding protein 1

2

6

High-throughput

0.608

High

362366

ABL1
Tyrosine-protein kinase ABL1

1

13

High-throughput

0.590

High

842664

WASP
Actin nucleation-promoting factor WAS

2

20

Small-scale

0.584

High

840982

ABL2
Tyrosine-protein kinase ABL2

1

13

High-throughput

0.575

High

530330

TAU
Microtubule-associated protein tau

1

9

Small-scale

0.573

High

1325133

MILK1
MICAL-like protein 1

2

5

Small-scale

0.571

High

1059949

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

2

8

Small-scale

0.563

High

1417655

PICK1
PRKCA-binding protein

1

3

Small-scale

0.561

High

1417654

JADE2
E3 ubiquitin-protein ligase Jade-2

2

1

High-throughput

0.555

High

1417652

PKHF2
Pleckstrin homology domain-containing family F member 2

2

2

High-throughput

0.553

High

332039

KAT7
Histone acetyltransferase KAT7

1

2

High-throughput

0.541

High

1028863

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

4

High-throughput

0.541

High

1316145

RTKN2
Rhotekin-2

1

4

High-throughput

0.541

High

1417656

POTE1
Protection of telomeres protein 1

1

2

High-throughput

0.523

High

391658

FRIH
Ferritin heavy chain

1

0

High-throughput

0.518

High

995469

TPM4
Tropomyosin alpha-4 chain

1

0

High-throughput

0.518

High

1417661

SNX12
Sorting nexin-12

1

3

High-throughput

0.515

High

370231

CYTN
Cystatin-SN

1

0

High-throughput

0.513

High

215948

SYNJ1
Synaptojanin-1

1

9

Small-scale

0.501

High

1315287

SLN12
Ribonuclease SLFN12

1

0

High-throughput

0.493

High

791686

SYUA
Alpha-synuclein

1

1

High-throughput

0.481

High

161079

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

19

Small-scale

0.479

High

219560

WIPF1
WAS/WASL-interacting protein family member 1

1

20

Small-scale

0.479

High

373060

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.479

High

409064

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

1

High-throughput

0.479

High

417726

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.479

High

537841

HSP7C
Heat shock cognate 71 kDa protein

1

3

Small-scale

0.479

High

620565

NUCL
Nucleolin

1

1

High-throughput

0.479

High

838506

GRIA2
Glutamate receptor 2

1

5

Small-scale

0.479

High

838532

GRIA3
Glutamate receptor 3

1

5

Small-scale

0.479

High

884605

SYCC
Cysteine--tRNA ligase, cytoplasmic

1

4

Small-scale

0.479

High

896877

DYN2
Dynamin-2

1

20

Small-scale

0.479

High

1008450

ADA17
Disintegrin and metalloproteinase domain-containing protein 17

1

19

Small-scale

0.479

High

1279425

AB1IP
Amyloid beta A4 precursor protein-binding family B member 1-interacting protein

1

13

Small-scale

0.479

High

1390209

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

5

Small-scale

0.479

High

1414772

TRAF4
TNF receptor-associated factor 4

1

1

Small-scale

0.479

High

1417664

TRAF6
TNF receptor-associated factor 6

1

3

Small-scale

0.479

High

143908

NDKM
Nucleoside diphosphate kinase, mitochondrial

1

1

High-throughput

0.470

High

717977

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

0

High-throughput

0.458

High

1360066

NELFB
Negative elongation factor B

1

0

High-throughput

0.458

High

930044

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

1

High-throughput

0.457

High

965861

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

2

High-throughput

0.457

High

978700

RL23A
Large ribosomal subunit protein uL23

1

2

High-throughput

0.457

High

990687

1433Z
14-3-3 protein zeta/delta

1

9

High-throughput

0.457

High

1017399

ALEX
Protein ALEX

1

5

High-throughput

0.457

High

1040367

DYST
Dystonin

1

6

High-throughput

0.457

High

1060694

SOS1
Son of sevenless homolog 1

1

12

High-throughput

0.457

High

1070513

FCHO2
F-BAR domain only protein 2

1

18

High-throughput

0.457

High

1417657

EHD3
EH domain-containing protein 3

1

20

High-throughput

0.457

High

1241113

C2D1A
Coiled-coil and C2 domain-containing protein 1A

1

6

High-throughput

0.445

High

1353771

WIPF2
WAS/WASL-interacting protein family member 2

1

7

High-throughput

0.445

High

1417653

TRPV4
Transient receptor potential cation channel subfamily V member 4

1

1

High-throughput

0.445

High

1417663

3BP1
SH3 domain-binding protein 1

1

19

High-throughput

0.445

High

1130717

DIP2A
Disco-interacting protein 2 homolog A

1

0

High-throughput

0.438

High

1324560

S66A2
Solute carrier family 66 member 2

1

0

High-throughput

0.438

High

1390462

PHIPL
Phytanoyl-CoA hydroxylase-interacting protein-like

1

0

High-throughput

0.438

High

106594

APRIO
Alternative prion protein

1

5

High-throughput

0.437

High

176367

SYNEM
Synemin

1

6

Small-scale

0.437

High

321936

FRYL
Protein furry homolog-like

1

1

High-throughput

0.417

High

473046

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

3

High-throughput

0.417

High

794610

RBMX
RNA-binding motif protein, X chromosome

1

1

High-throughput

0.417

High

397810

ATP8
ATP synthase F(0) complex subunit 8

1

0

High-throughput

0.282

High

1239115

RWDD4
RWD domain-containing protein 4

1

0

High-throughput

0.279

Low

1410206

CMS1
Protein CMSS1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025