Protein: VPS21
Vacuolar protein sorting-associated protein 21 (GTP-binding protein YPT51) (Vacuolar protein-targeting protein 12)

Gene: VPS21
Organism: Saccharomyces cerevisiae S288C
Interactions: 87
UniProt ID: P36017

Gene Ontology (top 5):
GO:0000011 - vacuole inheritance
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

699419

RAEP
Rab proteins geranylgeranyltransferase component A

4

20

High-throughput

0.904

High

696766

PEP7
Vacuolar segregation protein PEP7

4

18

Small-scale

0.889

High

731194

VPS9
Vacuolar protein sorting-associated protein 9

3

20

Small-scale

0.870

High

731176

GDI1
Rab GDP-dissociation inhibitor

8

20

Small-scale

0.867

High

731185

GYP3
GTPase-activating protein GYP3

3

20

Small-scale

0.863

High

731167

YPT53
GTP-binding protein YPT53

2

18

Small-scale

0.808

High

731166

YPT52
GTP-binding protein YPT52

2

18

Small-scale

0.793

High

731165

VPS21
Vacuolar protein sorting-associated protein 21

2

16

Small-scale

0.776

High

731174

VPS8
Vacuolar protein sorting-associated protein 8

7

6

Small-scale

0.741

High

731198

MUK1
Protein MUK1

2

0

Small-scale

0.737

High

619690

VPS3
Vacuolar protein sorting-associated protein 3

5

1

Small-scale

0.710

High

419746

RHO2
GTP-binding protein RHO2

1

20

High-throughput

0.691

High

614604

KC11
Casein kinase I homolog 1

1

11

High-throughput

0.691

High

731169

YPT10
GTP-binding protein YPT10

1

20

Small-scale

0.680

High

731207

GYP1
GTPase-activating protein GYP1

1

20

Small-scale

0.647

High

474336

U5072
UPF0507 protein YML002W

1

1

Small-scale

0.621

High

701759

YPT7
Ypt/Rab-type GTPase YPT7

1

20

Small-scale

0.621

High

731211

YPT6
GTP-binding protein YPT6

1

19

Small-scale

0.621

High

618323

STE11
Serine/threonine-protein kinase STE11

1

4

High-throughput

0.618

High

510880

SSB1
Ribosome-associated molecular chaperone SSB1

2

14

High-throughput

0.618

High

606255

VPS15
Serine/threonine-protein kinase VPS15

1

12

High-throughput

0.618

High

608943

VPS34
Phosphatidylinositol 3-kinase VPS34

1

20

High-throughput

0.618

High

696492

TOR2
Serine/threonine-protein kinase TOR2

1

11

Small-scale

0.618

High

543535

HSC82
ATP-dependent molecular chaperone HSC82

2

12

High-throughput

0.594

High

648141

KCC1
Calcium/calmodulin-dependent protein kinase I

1

2

High-throughput

0.579

High

731172

RCK1
Serine/threonine-protein kinase RCK1

1

5

High-throughput

0.579

High

731200

TDA1
Serine/threonine-protein kinase TDA1

1

7

High-throughput

0.579

High

731191

YIF1
Protein transport protein YIF1

2

7

Small-scale

0.543

High

701251

VAM7
Vacuolar morphogenesis protein 7

1

6

Small-scale

0.541

High

731168

UGA2
Succinate-semialdehyde dehydrogenase [NADP(+)]

1

5

High-throughput

0.541

High

731186

HSV2
SVP1-like protein 2

1

6

High-throughput

0.541

High

731187

YIP1
Protein transport protein YIP1

2

11

Small-scale

0.533

High

731183

JJJ2
J protein JJJ2

1

5

High-throughput

0.514

High

731196

TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

1

0

High-throughput

0.513

High

731190

PRA1
Prenylated Rab acceptor 1

1

20

Small-scale

0.508

High

589533

PGTB2
Geranylgeranyl transferase type-2 subunit beta

1

8

Small-scale

0.501

High

731195

PGTA
Geranylgeranyl transferase type-2 subunit alpha

1

8

Small-scale

0.501

High

334467

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

1

High-throughput

0.500

High

334916

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

1

High-throughput

0.500

High

425012

DHE4
NADP-specific glutamate dehydrogenase 1

1

2

High-throughput

0.500

High

430765

SYV
Valine--tRNA ligase, mitochondrial

1

1

High-throughput

0.500

High

505157

PYC1
Pyruvate carboxylase 1

1

3

High-throughput

0.500

High

664764

BMH1
Protein BMH1

1

3

High-throughput

0.500

High

712898

BMH2
Protein BMH2

1

3

High-throughput

0.500

High

713210

TSA1
Peroxiredoxin TSA1

1

3

High-throughput

0.500

High

731193

IDHH
Isocitrate dehydrogenase [NADP]

1

0

High-throughput

0.493

High

522448

PEP5
E3 ubiquitin-protein ligase PEP5

1

3

Small-scale

0.481

High

342700

ENO1
Enolase 1

1

0

High-throughput

0.479

High

404328

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

0

High-throughput

0.479

High

410973

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.479

High

584150

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.479

High

731175

SAHH
Adenosylhomocysteinase

1

0

High-throughput

0.479

High

546715

SEC23
Protein transport protein SEC23

1

7

High-throughput

0.479

High

680612

HS104
Heat shock protein 104

1

5

High-throughput

0.479

High

705031

HSP78
Heat shock protein 78, mitochondrial

1

5

High-throughput

0.479

High

731170

ATG8
Autophagy-related protein 8

1

7

High-throughput

0.479

High

731182

ATG27
Autophagy-related protein 27

1

2

High-throughput

0.479

High

731192

ATG2
Autophagy-related protein 2

1

4

High-throughput

0.479

High

731199

BECN1
Vacuolar protein sorting-associated protein 30

1

2

High-throughput

0.479

High

731208

ATG9
Autophagy-related protein 9

1

3

High-throughput

0.479

High

731209

ATG11
Autophagy-related protein 11

1

1

High-throughput

0.479

High

731188

YIP5
Protein YIP5

1

3

Small-scale

0.457

High

703781

PRS6B
26S proteasome regulatory subunit 6B homolog

1

1

High-throughput

0.457

High

490862

HSP71
Heat shock protein SSA1

1

11

High-throughput

0.445

High

493660

HSP72
Heat shock protein SSA2

1

11

High-throughput

0.445

High

731178

SSB2
Ribosome-associated molecular chaperone SSB2

1

14

High-throughput

0.445

High

731201

GRH1
GRASP65 homolog protein 1

1

6

High-throughput

0.445

High

731197

ULP1
Ubiquitin-like-specific protease 1

1

1

High-throughput

0.439

High

731206

VAM6
Vacuolar morphogenesis protein 6

1

18

Small-scale

0.439

High

697685

TFB1
General transcription and DNA repair factor IIH subunit TFB1

1

0

High-throughput

0.438

High

660313

PEX3
Peroxisomal biogenesis factor 3

1

1

High-throughput

0.437

High

661891

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

731171

ATG14
Autophagy-related protein 14

1

1

High-throughput

0.437

High

731179

SEC24
Protein transport protein SEC24

1

7

High-throughput

0.437

High

731203

SEC13
Protein transport protein SEC13

1

8

High-throughput

0.437

High

731205

ATG23
Autophagy-related protein 23

1

2

High-throughput

0.437

High

731181

PFD1
Prefoldin subunit 1

1

1

High-throughput

0.407

High

731173

ARO9
Aromatic amino acid aminotransferase 2

1

0

High-throughput

0.261

Low

731180

GPP1
Glycerol-1-phosphate phosphohydrolase 1

1

0

High-throughput

0.261

Low

728105

BLI1
Biogenesis of lysosome-related organelles complex 1 subunit BLI1

1

0

Small-scale

0.251

Low

731177

VAB2
Biogenesis of lysosome-related organelles complex 1 subunit VAB2

1

0

Small-scale

0.251

Low

731184

SNAPN
Biogenesis of lysosome-related organelles complex 1 subunit SNN1

1

0

Small-scale

0.251

Low

731189

KXD1
Biogenesis of lysosome-related organelles complex 1 subunit KXD1

1

0

Small-scale

0.251

Low

731204

BL1S4
Biogenesis of lysosome-related organelles complex 1 subunit CNL1

1

0

Small-scale

0.251

Low

731210

HUG1
MEC1-mediated checkpoint protein HUG1

1

0

High-throughput

0.238

Low

731202

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024