Protein: TTC1
Tetratricopeptide repeat protein 1 (TPR repeat protein 1)

Gene: TTC1
Organism: Homo sapiens
Interactions: 116
UniProt ID: Q99614

Gene Ontology (top 5):
GO:0005778 - peroxisomal membrane
GO:0005829 - cytosol
GO:0006457 - protein folding
GO:0051082 - unfolded protein binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1305049

RNF41
E3 ubiquitin-protein ligase NRDP1

9

9

Small-scale

0.756

High

1305057

VAPA
Vesicle-associated membrane protein-associated protein A

6

2

High-throughput

0.738

High

432194

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.691

High

1305045

SPSB2
SPRY domain-containing SOCS box protein 2

3

14

High-throughput

0.667

High

349589

RASH
GTPase HRas

1

3

Small-scale

0.665

High

310772

VAPB
Vesicle-associated membrane protein-associated protein B/C

5

2

High-throughput

0.659

High

504630

HSP7C
Heat shock cognate 71 kDa protein

3

20

Small-scale

0.656

High

323986

BAG2
BAG family molecular chaperone regulator 2

2

3

High-throughput

0.628

High

398294

PCCA
Propionyl-CoA carboxylase alpha chain, mitochondrial

2

6

High-throughput

0.628

High

1200607

NAA40
N-alpha-acetyltransferase 40

1

3

High-throughput

0.618

High

1305044

DNJC7
DnaJ homolog subfamily C member 7

1

20

High-throughput

0.618

High

863844

LIMK2
LIM domain kinase 2

3

7

High-throughput

0.609

High

1065700

SETB1
Histone-lysine N-methyltransferase SETDB1

3

3

High-throughput

0.609

High

1305047

SYT11
Synaptotagmin-11

3

4

High-throughput

0.609

High

1305068

SRPRB
Signal recognition particle receptor subunit beta

3

4

High-throughput

0.609

High

975199

ACY1
Aminoacylase-1

2

1

High-throughput

0.608

High

1305061

NB5R1
NADH-cytochrome b5 reductase 1

2

3

High-throughput

0.606

High

483661

ST1A4
Sulfotransferase 1A4

2

1

High-throughput

0.584

High

1254236

BICD2
Protein bicaudal D homolog 2

2

4

High-throughput

0.584

High

1268885

AKAP1
A-kinase anchor protein 1, mitochondrial

2

5

High-throughput

0.584

High

262082

PEX14
Peroxisomal membrane protein PEX14

2

0

Small-scale

0.563

High

714374

HSP74
Heat shock 70 kDa protein 4

1

20

Small-scale

0.561

High

1056282

I5P1
Inositol polyphosphate-5-phosphatase A

2

2

High-throughput

0.558

High

1016098

SRBP2
Sterol regulatory element-binding protein 2

1

4

High-throughput

0.541

High

258159

DNJB6
DnaJ homolog subfamily B member 6

1

19

High-throughput

0.536

High

320901

HS74L
Heat shock 70 kDa protein 4L

1

20

High-throughput

0.536

High

324571

BAG3
BAG family molecular chaperone regulator 3

1

2

High-throughput

0.536

High

1085653

HIF1A
Hypoxia-inducible factor 1-alpha

1

10

High-throughput

0.536

High

1170019

QSOX2
Sulfhydryl oxidase 2

1

3

High-throughput

0.536

High

1175127

TBA1A
Tubulin alpha-1A chain

1

13

High-throughput

0.536

High

1283449

SPSB4
SPRY domain-containing SOCS box protein 4

1

14

High-throughput

0.536

High

1285413

SPSB1
SPRY domain-containing SOCS box protein 1

1

14

High-throughput

0.536

High

1305055

SPHK1
Sphingosine kinase 1

1

1

High-throughput

0.536

High

1305056

HPBP1
Hsp70-binding protein 1

1

3

High-throughput

0.536

High

1305060

KLH14
Kelch-like protein 14

1

2

High-throughput

0.536

High

675593

GNA15
Guanine nucleotide-binding protein subunit alpha-15

1

8

Small-scale

0.535

High

391451

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

7

Small-scale

0.515

High

926625

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

6

Small-scale

0.515

High

388681

HSPB1
Heat shock protein beta-1

1

6

High-throughput

0.515

High

791902

HD
Huntingtin

1

2

High-throughput

0.515

High

1034192

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.513

High

1299533

SORC2
VPS10 domain-containing receptor SorCS2 [Cleaved into: SorCS2 122 kDa chain; SorCS2 104 kDa chain; SorCS2 18 kDa chain]

1

0

High-throughput

0.513

High

1305046

SIKE1
Suppressor of IKBKE 1

1

0

High-throughput

0.513

High

727790

SOX5
Transcription factor SOX-5

1

4

High-throughput

0.494

High

49077

PLS5
Phospholipid scramblase family member 5

1

1

High-throughput

0.489

High

277271

TUSC2
Tumor suppressor candidate 2

1

1

High-throughput

0.489

High

1305066

NTNG1
Netrin-G1

1

5

High-throughput

0.489

High

207828

PPIP1
Proline-serine-threonine phosphatase-interacting protein 1

1

2

High-throughput

0.481

High

1115747

CRY2
Cryptochrome-2

1

7

Small-scale

0.481

High

1305053

NDE1
Nuclear distribution protein nudE homolog 1

1

5

High-throughput

0.481

High

127042

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

2

High-throughput

0.479

High

148099

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

16

High-throughput

0.479

High

163182

XPO1
Exportin-1

1

5

High-throughput

0.479

High

257216

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

1

4

High-throughput

0.479

High

304871

MFN2
Mitofusin-2

1

2

High-throughput

0.479

High

339280

MOS
Proto-oncogene serine/threonine-protein kinase mos

1

4

High-throughput

0.479

High

411830

LCK
Tyrosine-protein kinase Lck

1

9

High-throughput

0.479

High

729344

VGFR3
Vascular endothelial growth factor receptor 3

1

7

High-throughput

0.479

High

779973

CCNF
Cyclin-F

1

4

High-throughput

0.479

High

825519

LMAN1
Protein ERGIC-53

1

4

High-throughput

0.479

High

871750

HSP72
Heat shock-related 70 kDa protein 2

1

20

High-throughput

0.479

High

886420

NAL12
NACHT, LRR and PYD domains-containing protein 12

1

7

High-throughput

0.479

High

897113

ACTZ
Alpha-centractin

1

11

High-throughput

0.479

High

1072809

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

2

High-throughput

0.479

High

1121101

GLE1
mRNA export factor GLE1

1

4

High-throughput

0.479

High

1135124

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

1

High-throughput

0.479

High

1204320

DYR2
Dihydrofolate reductase 2, mitochondrial

1

2

High-throughput

0.479

High

1239723

NHLC2
NHL repeat-containing protein 2

1

1

High-throughput

0.479

High

1267113

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

6

High-throughput

0.479

High

1305062

ANC2
Anaphase-promoting complex subunit 2

1

6

High-throughput

0.479

High

1305063

FZR1
Fizzy-related protein homolog

1

14

High-throughput

0.479

High

1305064

UBP18
Ubl carboxyl-terminal hydrolase 18

1

7

High-throughput

0.479

High

1305067

FIS1
Mitochondrial fission 1 protein

1

1

High-throughput

0.479

High

837646

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

8

Small-scale

0.470

High

660680

GRN
Progranulin

1

1

High-throughput

0.470

High

1305058

SH3B4
SH3 domain-binding protein 4

1

1

High-throughput

0.464

High

378141

PRIO
Major prion protein

1

3

High-throughput

0.445

High

483649

ST1A3
Sulfotransferase 1A3

1

1

High-throughput

0.445

High

529618

CFTR
Cystic fibrosis transmembrane conductance regulator

1

8

High-throughput

0.445

High

489615

OSTP
Osteopontin

1

2

Small-scale

0.439

High

72503

B4DE84
cDNA FLJ55955, highly similar to HECT domain and RCC1-like domain-containing protein 2

1

5

High-throughput

0.437

High

101107

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

159395

PLD2
Phospholipase D2

1

7

High-throughput

0.437

High

232460

KDM1A
Lysine-specific histone demethylase 1A

1

3

High-throughput

0.437

High

553523

RFA2
Replication protein A 32 kDa subunit

1

10

High-throughput

0.437

High

569997

CEBPB
CCAAT/enhancer-binding protein beta

1

8

High-throughput

0.437

High

652055

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

12

High-throughput

0.437

High

721250

RFA3
Replication protein A 14 kDa subunit

1

8

High-throughput

0.437

High

1026521

RFA4
Replication protein A 30 kDa subunit

1

10

High-throughput

0.437

High

1050582

SIM2
Single-minded homolog 2

1

10

High-throughput

0.437

High

1152058

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.437

High

1171389

TRI67
Tripartite motif-containing protein 67

1

18

High-throughput

0.437

High

1188771

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

5

High-throughput

0.437

High

1197679

NEK8
Serine/threonine-protein kinase Nek8

1

17

High-throughput

0.437

High

1199605

LBN
Limbin

1

2

High-throughput

0.437

High

1237191

PLD5
Inactive phospholipase D5

1

2

High-throughput

0.437

High

1252943

DJB14
DnaJ homolog subfamily B member 14

1

20

High-throughput

0.437

High

1285444

Q96BE0
Heat shock cognate 71 kDa protein

1

20

High-throughput

0.437

High

1286528

ENTR1
Endosome-associated-trafficking regulator 1

1

1

High-throughput

0.437

High

1305050

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

1

High-throughput

0.437

High

1305051

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

7

High-throughput

0.437

High

1305052

OCAD1
OCIA domain-containing protein 1

1

1

High-throughput

0.437

High

1305054

DJB12
DnaJ homolog subfamily B member 12

1

20

High-throughput

0.437

High

1305059

SEP10
Septin-10

1

2

High-throughput

0.437

High

1305065

DYN3
Dynamin-3

1

3

High-throughput

0.437

High

1305069

MTCH2
Mitochondrial carrier homolog 2

1

15

High-throughput

0.437

High

3299

A0A0S2Z528
Proline-serine-threonine phosphatase interacting protein 1 isoform 3

1

1

High-throughput

0.417

High

111092

I3L3G9
NudE neurodevelopment protein 1

1

4

High-throughput

0.417

High

78242

B5MC51
Protein phosphatase 1 regulatory subunit 14

1

10

High-throughput

0.407

High

123310

CBX4
E3 SUMO-protein ligase CBX4

1

0

High-throughput

0.279

Low

991947

SCN1B
Sodium channel subunit beta-1

1

0

High-throughput

0.279

Low

1305048

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

0

High-throughput

0.279

Low

1305070

RM42
Large ribosomal subunit protein mL42

1

0

High-throughput

0.279

Low

1256787

GANC
Neutral alpha-glucosidase C

1

0

High-throughput

0.269

Low

281846

WFS1
Wolframin

1

0

High-throughput

0.268

Low

944154

KCJ10
ATP-sensitive inward rectifier potassium channel 10

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024