Protein: SPC24
Kinetochore protein SPC24

Gene: SPC24
Organism: Saccharomyces cerevisiae S288C
Interactions: 160
UniProt ID: Q04477

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0007059 - chromosome segregation
GO:0008017 - microtubule binding
GO:0031134 - sister chromatid biorientation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

774076

NDC80
Kinetochore protein NDC80

27

0

Small-scale

0.941

High

708056

NUF2
Kinetochore protein NUF2

13

0

Small-scale

0.931

High

766823

SPC25
Kinetochore protein SPC25

27

0

Small-scale

0.737

High

798063

CENPT
Inner kinetochore subunit CNN1

8

0

Small-scale

0.723

High

775853

DSN1
Kinetochore-associated protein DSN1

10

0

Small-scale

0.721

High

867918

MPS1
Serine/threonine-protein kinase MPS1

4

1

Small-scale

0.689

High

763955

MTW1
Kinetochore-associated protein MTW1

5

0

Small-scale

0.686

High

979630

SPC24
Kinetochore protein SPC24

5

0

Small-scale

0.679

High

859672

SP105
Spindle pole body component SPC105

5

0

Small-scale

0.676

High

979634

MMR1
Mitochondrial MYO2 receptor-related protein 1

3

0

High-throughput

0.617

High

979636

HDA2
HDA1 complex subunit 2

3

0

High-throughput

0.617

High

979645

SMC5
Structural maintenance of chromosomes protein 5

2

1

High-throughput

0.595

High

865536

CNM67
Chaotic nuclear migration protein 67

2

1

High-throughput

0.576

High

979640

PRP11
Pre-mRNA-splicing factor PRP11

2

0

High-throughput

0.570

High

805168

STU2
Protein STU2

2

0

Small-scale

0.569

High

381484

GAL1
Galactokinase

2

0

Small-scale

0.569

High

748303

CENPU
Inner kinetochore subunit AME1

2

0

Small-scale

0.559

High

979649

NSL1
Kinetochore-associated protein NSL1

2

0

High-throughput

0.547

High

689293

SP110
Spindle pole body component 110

2

0

Small-scale

0.528

High

774243

MET18
DNA repair/transcription protein MET18/MMS19

1

0

High-throughput

0.513

High

334534

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

1

High-throughput

0.500

High

411087

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.500

High

688933

SMY1
Kinesin-related protein SMY1

1

0

High-throughput

0.493

High

703735

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.493

High

521156

RAD50
DNA repair protein RAD50

1

0

High-throughput

0.486

High

700800

SMC1
Structural maintenance of chromosomes protein 1

1

0

High-throughput

0.486

High

979637

CENPO
Inner kinetochore subunit MCM21

1

0

Small-scale

0.486

High

798291

CHA4
Activatory protein CHA4

1

1

High-throughput

0.481

High

815478

TEA1
TY1 enhancer activator

1

1

High-throughput

0.481

High

979641

ADY3
Accumulates dyads protein 3

1

1

High-throughput

0.481

High

512652

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.479

High

554737

HSP26
Heat shock protein 26

1

0

High-throughput

0.479

High

560792

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.479

High

636739

CDC48
Cell division control protein 48

1

0

High-throughput

0.479

High

452127

SWI1
SWI/SNF chromatin-remodeling complex subunit SWI1

1

0

High-throughput

0.460

High

586332

MED15
Mediator of RNA polymerase II transcription subunit 15

1

0

High-throughput

0.460

High

604613

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

Small-scale

0.460

High

635922

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

0

High-throughput

0.460

High

639242

MSH1
DNA mismatch repair protein MSH1, mitochondrial

1

0

High-throughput

0.460

High

698604

MRE11
Double-strand break repair protein MRE11

1

0

Small-scale

0.460

High

728755

BDF1
Bromodomain-containing factor 1

1

0

High-throughput

0.460

High

764238

NOC2
Nucleolar complex protein 2

1

0

Small-scale

0.460

High

772516

MED3
Mediator of RNA polymerase II transcription subunit 3

1

0

High-throughput

0.460

High

775942

MET28
Transcriptional activator of sulfur metabolism MET28

1

0

High-throughput

0.460

High

797256

GNA1
Glucosamine 6-phosphate N-acetyltransferase

1

0

High-throughput

0.460

High

841431

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.460

High

860217

POP6
Ribonucleases P/MRP protein subunit POP6

1

0

High-throughput

0.460

High

971104

HAP5
Transcriptional activator HAP5

1

0

High-throughput

0.460

High

979631

RSE1
Pre-mRNA-splicing factor RSE1

1

0

Small-scale

0.460

High

979635

RRP15
Ribosomal RNA-processing protein 15

1

0

High-throughput

0.460

High

979638

YL419
Putative ATP-dependent RNA helicase YLR419W

1

0

Small-scale

0.460

High

979644

YAP7
AP-1-like transcription factor YAP7

1

0

High-throughput

0.460

High

979646

MPC54
Meiotic plaque component protein 54

1

0

Small-scale

0.460

High

979647

YP216
Putative ISWI chromatin-remodeling complex subunit YPL216W

1

0

High-throughput

0.460

High

979648

SAS10
Something about silencing protein 10

1

0

High-throughput

0.460

High

979650

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.460

High

663256

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

812433

NNF1
Kinetochore-associated protein NNF1

1

0

High-throughput

0.458

High

860961

DAM1
DASH complex subunit DAM1

1

0

Small-scale

0.458

High

979149

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

334984

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

1

High-throughput

0.457

High

427296

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

1

High-throughput

0.457

High

540159

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

1

High-throughput

0.457

High

695481

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.445

High

756433

SPC97
Spindle pole body component SPC97

1

1

High-throughput

0.445

High

862652

SPC98
Spindle pole body component SPC98

1

1

High-throughput

0.445

High

765592

SAP1
Protein SAP1

1

1

High-throughput

0.439

High

823664

ASNS1
Asparagine synthetase [glutamine-hydrolyzing] 1

1

1

Small-scale

0.439

High

356006

H2B2
Histone H2B.2

1

0

High-throughput

0.426

High

356707

H4
Histone H4

1

0

High-throughput

0.426

High

416809

CDC31
Cell division control protein 31

1

0

High-throughput

0.426

High

492369

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

516234

KAR1
Cell division control protein KAR1

1

0

High-throughput

0.426

High

643030

BUB2
Mitotic check point protein BUB2

1

0

High-throughput

0.426

High

687892

NUD1
Protein NUD1

1

0

High-throughput

0.426

High

693156

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

0

High-throughput

0.426

High

705956

SPC29
Spindle pole component 29

1

0

High-throughput

0.426

High

728379

ASK1
DASH complex subunit ASK1

1

0

High-throughput

0.426

High

732517

SPC42
Spindle pole body component SPC42

1

0

High-throughput

0.426

High

734044

NU133
Nucleoporin NUP133

1

0

High-throughput

0.426

High

745874

NU170
Nucleoporin NUP170

1

0

High-throughput

0.426

High

747657

HSL7
Protein arginine N-methyltransferase HSL7

1

0

High-throughput

0.426

High

763719

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.426

High

767731

IMB4
Importin subunit beta-4

1

0

High-throughput

0.426

High

772788

NUP82
Nucleoporin NUP82

1

0

High-throughput

0.426

High

811049

NU192
Nucleoporin NUP192

1

0

High-throughput

0.426

High

811858

BFA1
Mitotic check point protein BFA1

1

0

High-throughput

0.426

High

862279

TBG
Tubulin gamma chain

1

0

High-throughput

0.426

High

887672

ACT
Actin

1

0

High-throughput

0.426

High

961485

CDC14
Tyrosine-protein phosphatase CDC14

1

0

High-throughput

0.426

High

977641

NUP53
Nucleoporin NUP53

1

0

High-throughput

0.426

High

977817

FIN1
Filament protein FIN1

1

0

High-throughput

0.426

High

979652

SFI1
Protein SFI1

1

0

High-throughput

0.426

High

979655

CENPI
Inner kinetochore subunit CTF3

1

0

High-throughput

0.426

High

541923

NSP1
Nucleoporin NSP1

1

1

High-throughput

0.407

High

823001

NUP57
Nucleoporin NUP57

1

2

High-throughput

0.407

High

830679

NU145
Nucleoporin NUP145

1

3

High-throughput

0.407

High

969360

NUP49
Nucleoporin NUP49/NSP49

1

2

High-throughput

0.407

High

859734

MPS2
Monopolar spindle protein 2

7

0

Small-scale

0.391

High

731355

DYHC
Dynein heavy chain, cytoplasmic

2

0

High-throughput

0.319

High

629773

STE50
Protein STE50

2

0

Small-scale

0.310

High

690559

CDC12
Cell division control protein 12

2

0

High-throughput

0.310

High

861110

YG3A
Uncharacterized protein YGR130C

2

0

High-throughput

0.310

High

678190

ZIP1
Synaptonemal complex protein ZIP1

2

0

High-throughput

0.304

High

767017

FIR1
Factor interacting with REF2

2

0

Small-scale

0.304

High

811222

MPS3
Spindle pole body assembly component MPS3

2

0

High-throughput

0.300

High

690975

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

0

High-throughput

0.279

Low

979654

GLT1
Glutamate synthase [NADH]

1

0

High-throughput

0.279

Low

976149

VPS60
Vacuolar protein-sorting-associated protein 60

1

0

High-throughput

0.269

Low

732862

DID4
DOA4-independent degradation protein 4

1

0

High-throughput

0.265

Low

342775

ENO1
Enolase 1

1

0

High-throughput

0.261

Low

378398

LEU3
3-isopropylmalate dehydrogenase

1

0

High-throughput

0.261

Low

381720

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

0

High-throughput

0.261

Low

440918

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

0

High-throughput

0.261

Low

556289

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.261

Low

604471

CLH
Clathrin heavy chain

1

0

High-throughput

0.261

Low

657276

URA7
CTP synthase 1

1

0

High-throughput

0.261

Low

763443

MET10
Sulfite reductase [NADPH] flavoprotein component

1

0

High-throughput

0.261

Low

345269

STF1
F(1)-ATPase inhibitor STF1, mitochondrial

1

0

High-throughput

0.251

Low

534526

HAP4
Transcriptional activator HAP4

1

0

High-throughput

0.251

Low

631048

SSK22
Serine/threonine-protein kinase SSK22

1

0

Small-scale

0.251

Low

690267

CDC3
Cell division control protein 3

1

0

High-throughput

0.251

Low

746125

ECM13
Protein ECM13

1

0

High-throughput

0.251

Low

750725

GRPE
GrpE protein homolog, mitochondrial

1

0

High-throughput

0.251

Low

752815

SYSM
Serine--tRNA ligase, mitochondrial

1

0

High-throughput

0.251

Low

764739

VPS52
Vacuolar protein sorting-associated protein 52

1

0

High-throughput

0.251

Low

766547

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.251

Low

767545

TSC11
Target of rapamycin complex 2 subunit TSC11

1

0

High-throughput

0.251

Low

768108

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

0

High-throughput

0.251

Low

768377

YE16
Uncharacterized protein YER186C

1

0

High-throughput

0.251

Low

773873

BNR1
BNI1-related protein 1

1

0

High-throughput

0.251

Low

783890

BUD6
Bud site selection protein 6

1

0

Small-scale

0.251

Low

784555

MID1
Stretch-activated cation channel MID1

1

0

Small-scale

0.251

Low

797088

FMP32
Protein FMP32, mitochondrial

1

0

High-throughput

0.251

Low

797230

BUD27
Bud site selection protein 27

1

0

High-throughput

0.251

Low

810981

YJE9
Uncharacterized protein YJL049W

1

0

High-throughput

0.251

Low

816870

SNAPN
Biogenesis of lysosome-related organelles complex 1 subunit SNN1

1

0

High-throughput

0.251

Low

859050

MDS3
Negative regulator of sporulation MDS3

1

0

Small-scale

0.251

Low

859719

KXD1
Biogenesis of lysosome-related organelles complex 1 subunit KXD1

1

0

High-throughput

0.251

Low

860684

NNF2
Protein NNF2

1

0

High-throughput

0.251

Low

959867

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.251

Low

977470

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

High-throughput

0.251

Low

977794

SPO71
Prospore membrane adapter protein SPO71

1

0

Small-scale

0.251

Low

979632

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.251

Low

979633

HOB2
Protein YPR117W

1

0

High-throughput

0.251

Low

979639

MDM36
Mitochondrial distribution and morphology protein 36

1

0

High-throughput

0.251

Low

979643

YL031
Putative uncharacterized protein YLR031W

1

0

High-throughput

0.251

Low

979653

NCA2
Nuclear control of ATPase protein 2

1

0

High-throughput

0.251

Low

979656

VPS5
Vacuolar protein sorting-associated protein 5

1

0

High-throughput

0.251

Low

979657

HPH1
Protein HPH1

1

0

High-throughput

0.251

Low

979642

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

Small-scale

0.249

Low

691714

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.232

Low

709350

NIC96
Nucleoporin NIC96

1

0

High-throughput

0.232

Low

728211

NU120
Nucleoporin NUP120

1

0

High-throughput

0.232

Low

757341

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.232

Low

784287

VATH
V-type proton ATPase subunit H

1

0

High-throughput

0.232

Low

854938

NU188
Nucleoporin NUP188

1

0

High-throughput

0.232

Low

857438

NBP1
NAP1-binding protein

1

0

High-throughput

0.232

Low

979651

BBP1
Spindle pole component BBP1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024