Protein: LHX6
LIM/homeobox protein Lhx6 (LIM homeobox protein 6) (LIM/homeobox protein Lhx6.1)

Gene: LHX6
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q9UPM6

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1199149

LDB1
LIM domain-binding protein 1

7

20

High-throughput

0.971

High

1357653

SATB2
DNA-binding protein SATB2

3

7

High-throughput

0.861

High

1163324

FIGLA
Factor in the germline alpha

2

12

High-throughput

0.783

High

946674

SSBP2
Single-stranded DNA-binding protein 2

4

20

High-throughput

0.699

High

1314660

SSBP4
Single-stranded DNA-binding protein 4

4

20

High-throughput

0.699

High

1314911

SSBP3
Single-stranded DNA-binding protein 3

4

20

High-throughput

0.699

High

238123

LMX1B
LIM homeobox transcription factor 1-beta

1

19

High-throughput

0.691

High

782400

KDM5C
Lysine-specific demethylase 5C

3

7

High-throughput

0.667

High

1102968

QRIC1
Transcriptional regulator QRICH1

3

16

High-throughput

0.667

High

1135504

RN187
E3 ubiquitin-protein ligase RNF187

3

4

High-throughput

0.667

High

1199550

TLK2
Serine/threonine-protein kinase tousled-like 2

3

3

High-throughput

0.667

High

1218111

ARI3B
AT-rich interactive domain-containing protein 3B

3

20

High-throughput

0.667

High

1253721

ZN507
Zinc finger protein 507

3

8

High-throughput

0.667

High

1310393

NUD22
Uridine diphosphate glucose pyrophosphatase NUDT22

3

1

High-throughput

0.667

High

1357654

CARD8
Caspase recruitment domain-containing protein 8

3

1

High-throughput

0.667

High

1125908

BCORL
BCL-6 corepressor-like protein 1

1

8

High-throughput

0.618

High

1148497

LHX8
LIM/homeobox protein Lhx8

1

19

High-throughput

0.618

High

1296441

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

14

High-throughput

0.618

High

1357652

TRI33
E3 ubiquitin-protein ligase TRIM33

2

12

High-throughput

0.611

High

1357656

SALL2
Sal-like protein 2

2

3

High-throughput

0.611

High

1357657

WIPI4
WD repeat domain phosphoinositide-interacting protein 4

3

2

High-throughput

0.609

High

735118

ZNF76
Zinc finger protein 76

2

7

High-throughput

0.606

High

855996

ZN138
Zinc finger protein 138

2

3

High-throughput

0.606

High

884267

KLF3
Krueppel-like factor 3

2

13

High-throughput

0.606

High

968517

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

2

13

High-throughput

0.606

High

1085291

NRF1
Nuclear respiratory factor 1

2

3

High-throughput

0.606

High

1306638

CPNE1
Copine-1

2

1

High-throughput

0.606

High

966669

OTUD4
OTU domain-containing protein 4

2

0

High-throughput

0.585

High

1046812

TF2H2
General transcription factor IIH subunit 2

2

0

High-throughput

0.585

High

388802

HSPB1
Heat shock protein beta-1

1

3

High-throughput

0.515

High

742611

SYUA
Alpha-synuclein

1

2

High-throughput

0.515

High

792097

HD
Huntingtin

1

3

High-throughput

0.515

High

868371

ATX3
Ataxin-3

1

1

High-throughput

0.515

High

868805

ATX1
Ataxin-1

1

6

High-throughput

0.515

High

1357655

RNF11
RING finger protein 11

1

3

High-throughput

0.515

High

946331

BASP1
Brain acid soluble protein 1

1

2

High-throughput

0.500

High

167175

ZN536
Zinc finger protein 536

1

5

High-throughput

0.479

High

473577

ATX1L
Ataxin-1-like

1

6

High-throughput

0.479

High

550446

ZEP1
Zinc finger protein 40

1

17

High-throughput

0.479

High

741104

ZEB1
Zinc finger E-box-binding homeobox 1

1

7

High-throughput

0.479

High

867667

BLM
RecQ-like DNA helicase BLM

1

3

High-throughput

0.479

High

980912

TLE3
Transducin-like enhancer protein 3

1

10

High-throughput

0.479

High

1147495

ARID2
AT-rich interactive domain-containing protein 2

1

20

High-throughput

0.479

High

1173278

PAXI1
PAX-interacting protein 1

1

12

High-throughput

0.479

High

1199217

PB1
Protein polybromo-1

1

15

High-throughput

0.479

High

1200133

BCL9L
B-cell CLL/lymphoma 9-like protein

1

20

High-throughput

0.479

High

1218470

WDFY1
WD repeat and FYVE domain-containing protein 1

1

3

High-throughput

0.479

High

1245609

KDM2B
Lysine-specific demethylase 2B

1

5

High-throughput

0.479

High

1259980

PHF10
PHD finger protein 10

1

20

High-throughput

0.479

High

1268311

ZN516
Zinc finger protein 516

1

6

High-throughput

0.479

High

1286166

ZBTB9
Zinc finger and BTB domain-containing protein 9

1

6

High-throughput

0.479

High

1301002

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1342840

BRD7
Bromodomain-containing protein 7

1

7

High-throughput

0.479

High

1357658

ZSC21
Zinc finger and SCAN domain-containing protein 21

1

7

High-throughput

0.479

High

47326

A0A6Q8PF08
Peripheral myelin protein 22

1

1

High-throughput

0.470

High

281950

WFS1
Wolframin

1

1

High-throughput

0.470

High

660759

GRN
Progranulin

1

1

High-throughput

0.470

High

1301301

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

833372

TMEDA
Transmembrane emp24 domain-containing protein 10

1

4

High-throughput

0.457

High

1313976

TMED9
Transmembrane emp24 domain-containing protein 9

1

3

High-throughput

0.457

High

131751

BCL9
B-cell CLL/lymphoma 9 protein

1

20

High-throughput

0.437

High

1286037

ATG2B
Autophagy-related protein 2 homolog B

3

0

High-throughput

0.347

High

1205649

F90A1
Protein FAM90A1

2

0

High-throughput

0.316

High

156686

PAHX
Phytanoyl-CoA dioxygenase, peroxisomal

1

0

High-throughput

0.268

Low

344595

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.268

Low

995468

LG3BP
Galectin-3-binding protein

1

0

High-throughput

0.261

Low

398421

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024