Protein: CARB
Carbamoyl phosphate synthase arginine-specific large chain (CPS) (CPSase) (CPSase-arg) (EC 6.3.4.16) (EC 6.3.5.5) (Ammonium-dependent carbamoyl phosphate synthetase) (Arginine-specific carbamoyl phosphate synthetase, ammonia chain) (Carbamoyl phosphate synthase A) (CPS-A) (Glutamine-dependent carbamoyl phosphate synthetase)

Gene: CARB, CPA2
Organism: Saccharomyces cerevisiae S288C
Interactions: 69
UniProt ID: P03965

Gene Ontology (top 5):
GO:0004070 - aspartate carbamoyltransferase activity
GO:0004087 - carbamoyl-phosphate synthase (ammonia) activity
GO:0004088 - carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GO:0004151 - dihydroorotase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

372784

CARA
Carbamoyl phosphate synthase arginine-specific small chain

4

9

Small-scale

0.892

High

372785

PYR1
Multifunctional protein URA2

2

18

High-throughput

0.759

High

372806

URA7
CTP synthase 1

2

1

High-throughput

0.759

High

372804

RAD51
DNA repair protein RAD51

2

4

High-throughput

0.621

High

372794

HSC82
ATP-dependent molecular chaperone HSC82

2

6

High-throughput

0.584

High

372829

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

3

High-throughput

0.584

High

372790

SSB1
Ribosome-associated molecular chaperone SSB1

2

14

High-throughput

0.552

High

372783

FAS1
Fatty acid synthase subunit beta

1

3

High-throughput

0.536

High

372793

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

2

High-throughput

0.536

High

372812

EI2BB
Translation initiation factor eIF2B subunit beta

1

3

High-throughput

0.536

High

372816

PRS6B
26S proteasome regulatory subunit 6B homolog

1

1

High-throughput

0.536

High

372820

ATG12
Ubiquitin-like protein ATG12

1

1

High-throughput

0.536

High

372821

DBP8
ATP-dependent RNA helicase DBP8

1

1

High-throughput

0.536

High

372826

RFC2
Replication factor C subunit 2

1

2

High-throughput

0.536

High

372828

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.536

High

372833

KU80
ATP-dependent DNA helicase II subunit 2

1

1

High-throughput

0.536

High

372839

RUVB2
RuvB-like protein 2

1

3

High-throughput

0.536

High

372808

HRR25
Casein kinase I homolog HRR25

1

7

High-throughput

0.501

High

372838

YGK3
Glycogen synthase kinase-3 homolog YGK3

1

7

High-throughput

0.501

High

372797

PHO85
Cyclin-dependent protein kinase PHO85

1

8

High-throughput

0.500

High

372801

PP11
Serine/threonine-protein phosphatase PP1-1

1

3

High-throughput

0.500

High

372802

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

1

High-throughput

0.500

High

372810

ARP2
Actin-related protein 2

1

1

High-throughput

0.500

High

343058

THDH
Threonine dehydratase, mitochondrial

1

3

High-throughput

0.489

High

356140

H4
Histone H4

1

5

High-throughput

0.489

High

372840

CMR1
DNA damage-binding protein CMR1

1

13

High-throughput

0.481

High

372811

CDC3
Cell division control protein 3

1

0

High-throughput

0.479

High

343164

TRP
Tryptophan synthase

1

1

High-throughput

0.479

High

365507

HSP82
ATP-dependent molecular chaperone HSP82

1

6

High-throughput

0.479

High

372780

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

372782

SNF1
Carbon catabolite-derepressing protein kinase

1

5

Small-scale

0.479

High

372791

CAF20
Cap-associated protein CAF20

1

2

High-throughput

0.479

High

372798

MDHM
Malate dehydrogenase, mitochondrial

1

4

Small-scale

0.479

High

372803

SIS1
Protein SIS1

1

4

High-throughput

0.479

High

372807

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

372813

ZUO1
Zuotin

1

3

Small-scale

0.479

High

372815

PRS6A
26S proteasome regulatory subunit 6A

1

1

High-throughput

0.479

High

372822

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.479

High

372823

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.479

High

372831

SAP4
SIT4-associating protein SAP4

1

3

High-throughput

0.479

High

372834

SYRC
Arginine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.479

High

372837

VAM6
Vacuolar morphogenesis protein 6

1

3

High-throughput

0.479

High

341742

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.458

High

372789

AK
Aspartokinase

1

0

High-throughput

0.458

High

372795

SYFB
Phenylalanine--tRNA ligase beta subunit

1

0

High-throughput

0.458

High

372800

IF2A
Eukaryotic translation initiation factor 2 subunit alpha

1

0

High-throughput

0.458

High

372809

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

372830

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

0

High-throughput

0.458

High

372832

BUD32
EKC/KEOPS complex subunit BUD32

1

0

High-throughput

0.458

High

372786

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

3

High-throughput

0.457

High

360677

TBB
Tubulin beta chain

1

2

High-throughput

0.445

High

367577

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

372781

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.445

High

372787

TBA1
Tubulin alpha-1 chain

1

5

High-throughput

0.445

High

372788

HSP72
Heat shock protein SSA2

1

13

High-throughput

0.445

High

372792

DHAS
Aspartate-semialdehyde dehydrogenase

1

1

High-throughput

0.445

High

372817

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

1

High-throughput

0.445

High

372825

SSB2
Ribosome-associated molecular chaperone SSB2

1

14

High-throughput

0.445

High

372824

GGC1
Mitochondrial GTP/GDP carrier protein 1

1

3

High-throughput

0.437

High

334568

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

High-throughput

0.426

High

372796

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

372805

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

4

High-throughput

0.407

High

372814

SUI1
Eukaryotic translation initiation factor eIF-1

1

0

High-throughput

0.261

Low

372799

TEC1
Ty transcription activator TEC1

1

0

High-throughput

0.249

Low

372818

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

372819

POP7
Ribonucleases P/MRP protein subunit POP7

1

0

High-throughput

0.249

Low

372827

FIS1
Mitochondrial fission 1 protein

1

0

Small-scale

0.249

Low

372835

NKP2
Inner kinetochore subunit NKP2

1

0

High-throughput

0.249

Low

372836

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024