Protein: NTRK2
BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)

Gene: NTRK2
Organism: Homo sapiens
Interactions: 135
UniProt ID: Q16620

Gene Ontology (top 5):
GO:0001570 - vasculogenesis
GO:0001764 - neuron migration
GO:0001934 - positive regulation of protein phosphorylation
GO:0002020 - protease binding
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

581014

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

4

20

Small-scale

0.891

High

618271

BDNF
Brain-derived neurotrophic factor

3

9

Small-scale

0.858

High

338486

EGFR
Epidermal growth factor receptor

3

20

High-throughput

0.843

High

710107

NTF4
Neurotrophin-4

3

9

Small-scale

0.834

High

666119

SHC1
SHC-transforming protein 1

3

20

Small-scale

0.834

High

1083874

SHC3
SHC-transforming protein 3

3

20

Small-scale

0.829

High

573718

PTN1
Tyrosine-protein phosphatase non-receptor type 1

2

20

Small-scale

0.792

High

655389

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

2

20

Small-scale

0.757

High

412212

FYN
Tyrosine-protein kinase Fyn

1

20

Small-scale

0.724

High

1070970

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

Small-scale

0.724

High

1081496

NTRK3
NT-3 growth factor receptor

1

18

High-throughput

0.715

High

209065

NCK2
Cytoplasmic protein NCK2

1

20

Small-scale

0.680

High

595719

NTF3
Neurotrophin-3

1

9

Small-scale

0.647

High

1083850

NTRK2
BDNF/NT-3 growth factors receptor

1

18

Small-scale

0.637

High

383833

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

Small-scale

0.621

High

1083902

SH2B1
SH2B adapter protein 1

1

20

Small-scale

0.621

High

1083873

FRS2
Fibroblast growth factor receptor substrate 2

2

20

Small-scale

0.619

High

64712

RHG32
Rho GTPase-activating protein 32

1

20

High-throughput

0.618

High

118739

AIP
AH receptor-interacting protein

1

18

High-throughput

0.618

High

129300

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

20

High-throughput

0.618

High

146632

SOCS2
Suppressor of cytokine signaling 2

1

20

Small-scale

0.618

High

277074

STAM2
Signal transducing adapter molecule 2

1

20

High-throughput

0.618

High

557707

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.618

High

647902

MARK3
MAP/microtubule affinity-regulating kinase 3

1

10

High-throughput

0.618

High

665254

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.618

High

784019

KPCI
Protein kinase C iota type

1

19

High-throughput

0.618

High

924603

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.618

High

942352

DLG4
Disks large homolog 4

1

20

Small-scale

0.618

High

974084

DYST
Dystonin

1

20

High-throughput

0.618

High

980386

NOTC2
Neurogenic locus notch homolog protein 2

1

20

High-throughput

0.618

High

985963

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

20

High-throughput

0.618

High

992580

ACK1
Activated CDC42 kinase 1

1

20

Small-scale

0.618

High

1020168

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

20

High-throughput

0.618

High

1025293

LIPA1
Liprin-alpha-1

1

14

High-throughput

0.618

High

1031671

GRB10
Growth factor receptor-bound protein 10

1

20

Small-scale

0.618

High

1035376

GAB1
GRB2-associated-binding protein 1

1

20

High-throughput

0.618

High

1083860

SHC4
SHC-transforming protein 4

1

20

Small-scale

0.618

High

1083861

MPRIP
Myosin phosphatase Rho-interacting protein

1

20

High-throughput

0.618

High

1083863

LIPB1
Liprin-beta-1

1

19

High-throughput

0.618

High

1083868

MINK1
Misshapen-like kinase 1

1

20

High-throughput

0.618

High

1083875

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

1

20

High-throughput

0.618

High

1083879

ERBIN
Erbin

1

20

High-throughput

0.618

High

1083894

PEAK1
Inactive tyrosine-protein kinase PEAK1

1

19

High-throughput

0.618

High

1083898

E41L5
Band 4.1-like protein 5

1

20

High-throughput

0.618

High

1083906

DP13A
DCC-interacting protein 13-alpha

1

14

High-throughput

0.618

High

1083907

KDIS
Kinase D-interacting substrate of 220 kDa

1

16

High-throughput

0.618

High

1083909

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

1

18

High-throughput

0.618

High

1083882

SORT
Sortilin

1

7

Small-scale

0.589

High

1036611

SQSTM
Sequestosome-1

2

11

Small-scale

0.584

High

777045

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

11

Small-scale

0.578

High

150581

ABLM1
Actin-binding LIM protein 1

1

10

High-throughput

0.553

High

315834

AGRL2
Adhesion G protein-coupled receptor L2

1

3

High-throughput

0.553

High

1083857

PHLB3
Pleckstrin homology-like domain family B member 3

1

14

High-throughput

0.553

High

1083890

TARA
TRIO and F-actin-binding protein

1

19

High-throughput

0.553

High

1083910

ANR26
Ankyrin repeat domain-containing protein 26

1

16

High-throughput

0.553

High

1083885

NFIP1
NEDD4 family-interacting protein 1

1

2

Small-scale

0.552

High

1014018

AP1B1
AP-1 complex subunit beta-1

1

14

High-throughput

0.541

High

1082785

CDC37
Hsp90 co-chaperone Cdc37

1

20

High-throughput

0.536

High

1083897

NMNA1
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

1

0

High-throughput

0.518

High

444736

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

7

High-throughput

0.500

High

158191

GIPC1
PDZ domain-containing protein GIPC1

1

4

Small-scale

0.479

High

160015

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

20

High-throughput

0.479

High

164126

ARHGA
Rho guanine nucleotide exchange factor 10

1

20

High-throughput

0.479

High

227584

PRKN
E3 ubiquitin-protein ligase parkin

1

10

High-throughput

0.479

High

253565

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

1

20

High-throughput

0.479

High

310655

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

20

High-throughput

0.479

High

313542

ZFYV9
Zinc finger FYVE domain-containing protein 9

1

20

High-throughput

0.479

High

315708

SC24B
Protein transport protein Sec24B

1

20

High-throughput

0.479

High

377358

GCR
Glucocorticoid receptor

1

8

Small-scale

0.479

High

431901

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.479

High

436626

TNR16
Tumor necrosis factor receptor superfamily member 16

1

15

Small-scale

0.479

High

438213

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.479

High

588608

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

10

High-throughput

0.479

High

602908

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

3

Small-scale

0.479

High

742323

SYUA
Alpha-synuclein

1

1

Small-scale

0.479

High

787377

PK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

1

20

High-throughput

0.479

High

841980

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

1

18

High-throughput

0.479

High

920979

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

12

High-throughput

0.479

High

971016

DSC2
Desmocollin-2

1

20

High-throughput

0.479

High

984267

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

2

Small-scale

0.479

High

1052408

FLOT2
Flotillin-2

1

15

High-throughput

0.479

High

1071535

L2GL1
Lethal(2) giant larvae protein homolog 1

1

4

High-throughput

0.479

High

1074039

SC23B
Protein transport protein Sec23B

1

20

High-throughput

0.479

High

1083851

OCLN
Occludin

1

5

High-throughput

0.479

High

1083852

GRDN
Girdin

1

19

High-throughput

0.479

High

1083853

PLCH1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1

1

20

High-throughput

0.479

High

1083854

DCAF6
DDB1- and CUL4-associated factor 6

1

20

High-throughput

0.479

High

1083855

F1711
Protein FAM171A1

1

20

High-throughput

0.479

High

1083856

STEA3
Metalloreductase STEAP3

1

3

High-throughput

0.479

High

1083862

GRIN3
G protein-regulated inducer of neurite outgrowth 3

1

12

High-throughput

0.479

High

1083864

LSR
Lipolysis-stimulated lipoprotein receptor

1

6

High-throughput

0.479

High

1083867

CBARP
Voltage-dependent calcium channel beta subunit-associated regulatory protein

1

1

High-throughput

0.479

High

1083869

CNNM3
Metal transporter CNNM3

1

3

High-throughput

0.479

High

1083870

VANG1
Vang-like protein 1

1

12

High-throughput

0.479

High

1083871

DLG5
Disks large homolog 5

1

18

High-throughput

0.479

High

1083872

PARD3
Partitioning defective 3 homolog

1

20

High-throughput

0.479

High

1083876

US6NL
USP6 N-terminal-like protein

1

18

High-throughput

0.479

High

1083880

RANB9
Ran-binding protein 9

1

11

Small-scale

0.479

High

1083883

CDCA3
Cell division cycle-associated protein 3

1

13

High-throughput

0.479

High

1083884

PKP2
Plakophilin-2

1

20

High-throughput

0.479

High

1083886

RFIP5
Rab11 family-interacting protein 5

1

12

High-throughput

0.479

High

1083887

SPY4
Protein sprouty homolog 4

1

3

High-throughput

0.479

High

1083888

ZDHC5
Palmitoyltransferase ZDHHC5

1

3

High-throughput

0.479

High

1083891

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

7

High-throughput

0.479

High

1083893

CENPH
Centromere protein H

1

2

High-throughput

0.479

High

1083896

PPIP2
Proline-serine-threonine phosphatase-interacting protein 2

1

19

High-throughput

0.479

High

1083899

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

20

High-throughput

0.479

High

1083900

JPH1
Junctophilin-1

1

8

High-throughput

0.479

High

1083901

WDR6
tRNA

1

20

High-throughput

0.479

High

1083904

S53A1
Solute carrier family 53 member 1

1

2

High-throughput

0.479

High

1083905

TRM7
tRNA

1

7

High-throughput

0.479

High

1083908

MYO6
Unconventional myosin-VI

1

12

High-throughput

0.479

High

1083911

NISCH
Nischarin

1

20

High-throughput

0.479

High

1083912

DTNA
Dystrobrevin alpha

1

8

High-throughput

0.479

High

1083913

TRAF6
TNF receptor-associated factor 6

1

12

Small-scale

0.479

High

1083914

UBIA1
UbiA prenyltransferase domain-containing protein 1

1

1

High-throughput

0.479

High

1083915

S4A7
Sodium bicarbonate cotransporter 3

1

4

High-throughput

0.479

High

994703

S20A2
Sodium-dependent phosphate transporter 2

1

0

High-throughput

0.458

High

1083889

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

240017

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

7

High-throughput

0.445

High

1047105

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

8

High-throughput

0.445

High

1083877

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

18

High-throughput

0.445

High

1083878

VPS35
Vacuolar protein sorting-associated protein 35

1

2

Small-scale

0.445

High

1083881

SCN2A
Sodium channel protein type 2 subunit alpha

1

8

High-throughput

0.445

High

68174

F1712
Protein FAM171A2

1

20

High-throughput

0.437

High

1075830

TRIPB
Thyroid receptor-interacting protein 11

1

20

High-throughput

0.437

High

1083858

F171B
Protein FAM171B

1

20

High-throughput

0.437

High

1083859

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

9

High-throughput

0.437

High

1083865

DZIP1
Cilium assembly protein DZIP1

1

14

High-throughput

0.437

High

1083866

M21D2
Nucleotidyltransferase MB21D2

1

7

High-throughput

0.437

High

1083892

GCP60
Golgi resident protein GCP60

1

15

High-throughput

0.437

High

1083895

GORS2
Golgi reassembly-stacking protein 2

1

12

High-throughput

0.437

High

1083903

F135A
Protein FAM135A

1

4

High-throughput

0.437

High

913900

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

0

High-throughput

0.282

High


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Last updated: 15 Jul 2024