HitPredict - High confidence protein-protein interactions

Protein: LYCHS
Lysosomal cholesterol signaling protein (LYCHOS) (G-protein coupled receptor PGR22)

Gene: LYCHS, GPR155
Organism: Homo sapiens
Interactions: 6
UniProt ID: Q7Z3F1

Gene Ontology (top 5):
GO:0005765 - lysosomal membrane
GO:0015485 - cholesterol binding
GO:0030514 - negative regulation of BMP signaling pathway
GO:0034198 - cellular response to amino acid starvation
GO:0035556 - intracellular signal transduction

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
562170	LAMP2 Lysosome-associated membrane glycoprotein 2	1	3	High-throughput	0.479	High
1277086	LAMP3 Lysosome-associated membrane glycoprotein 3	1	3	High-throughput	0.479	High
669019	FPR2 N-formyl peptide receptor 2	2	0	High-throughput	0.328	High
351231	MOT3 Monocarboxylate transporter 3	1	0	High-throughput	0.232	Low
1242149	NPAL3 NIPA-like protein 3	1	0	High-throughput	0.232	Low
1277085	S35C2 Solute carrier family 35 member C2	1	0	High-throughput	0.232	Low

Service provided by Combinatics, Japan

Last updated: 11Aug2025