Protein: PKH2
Serine/threonine-protein kinase PKH2 (EC 2.7.11.1) (PKB-activating kinase homolog 2)

Gene: PKH2
Organism: Saccharomyces cerevisiae S288C
Interactions: 76
UniProt ID: Q12236

Gene Ontology (top 5):
GO:0000196 - cell wall integrity MAPK cascade
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

976286

PKH1
Serine/threonine-protein kinase PKH1

2

18

High-throughput

0.743

High

1015361

PKH2
Serine/threonine-protein kinase PKH2

2

19

High-throughput

0.743

High

339908

CDK1
Cyclin-dependent kinase 1

1

9

High-throughput

0.724

High

860644

PIL1
Sphingolipid long chain base-responsive protein PIL1

4

4

Small-scale

0.690

High

1015351

LSP1
Sphingolipid long chain base-responsive protein LSP1

3

4

Small-scale

0.664

High

515211

SCH9
Serine/threonine-protein kinase SCH9

1

19

High-throughput

0.647

High

608821

KCC2
Calcium/calmodulin-dependent protein kinase II

1

20

High-throughput

0.647

High

623515

KPC1
Protein kinase C-like 1

1

18

Small-scale

0.647

High

701821

YPT7
Ypt/Rab-type GTPase YPT7

1

6

High-throughput

0.647

High

811995

DOHH
Deoxyhypusine hydroxylase

1

1

High-throughput

0.647

High

812343

DPH4
Diphthamide biosynthesis protein 4

1

17

High-throughput

0.647

High

866771

CRZ1
Transcriptional regulator CRZ1

1

5

High-throughput

0.647

High

994066

NOP12
Nucleolar protein 12

1

15

High-throughput

0.618

High

753481

RIM4
Meiotic activator RIM4

1

14

High-throughput

0.579

High

605183

XRN1
5'-3' exoribonuclease 1

2

0

High-throughput

0.569

High

812304

BUD4
Bud site selection protein 4

1

0

High-throughput

0.541

High

743738

HMT1
Protein arginine N-methyltransferase 1

1

3

Small-scale

0.541

High

991707

FMP45
SUR7 family protein FMP45

1

0

High-throughput

0.518

High

715252

TOR1
Serine/threonine-protein kinase TOR1

1

17

High-throughput

0.515

High

485863

IF4A
ATP-dependent RNA helicase eIF4A

1

15

High-throughput

0.501

High

549282

SYFB
Phenylalanine--tRNA ligase beta subunit

1

1

High-throughput

0.501

High

572069

CLC1
Clathrin light chain

1

1

High-throughput

0.501

High

585879

RDS2
Regulator of drug sensitivity 2

1

1

High-throughput

0.501

High

635541

RSC6
Chromatin structure-remodeling complex protein RSC6

1

1

High-throughput

0.501

High

648341

GYS2
Glycogen [starch] synthase isoform 2

1

2

High-throughput

0.501

High

699751

DRS1
ATP-dependent RNA helicase DRS1

1

18

High-throughput

0.501

High

699818

KPR1
Ribose-phosphate pyrophosphokinase 1

1

9

High-throughput

0.501

High

703760

PRS6A
26S proteasome regulatory subunit 6A

1

10

High-throughput

0.501

High

710587

UBX1
UBX domain-containing protein 1

1

5

High-throughput

0.501

High

761109

TCPZ
T-complex protein 1 subunit zeta

1

20

High-throughput

0.501

High

768167

RTR1
RNA polymerase II subunit B1 CTD phosphatase RTR1

1

2

High-throughput

0.501

High

774548

SHQ1
Protein SHQ1

1

1

High-throughput

0.501

High

980146

CSM3
Chromosome segregation in meiosis protein 3

1

1

High-throughput

0.501

High

342141

ATPB
ATP synthase subunit beta, mitochondrial

1

7

High-throughput

0.500

High

634209

SRO9
RNA-binding protein SRO9

1

5

High-throughput

0.500

High

759019

HXT6
High-affinity hexose transporter HXT6

1

3

High-throughput

0.489

High

759044

HXT7
High-affinity hexose transporter HXT7

1

3

High-throughput

0.489

High

629677

RV161
Reduced viability upon starvation protein 161

1

2

High-throughput

0.481

High

979578

MYO5
Myosin-5

1

18

Small-scale

0.481

High

753604

YAP3
AP-1-like transcription factor YAP3

1

0

High-throughput

0.480

High

809692

DPOD2
DNA polymerase delta small subunit

1

0

High-throughput

0.480

High

812450

NNF1
Kinetochore-associated protein NNF1

1

0

High-throughput

0.480

High

1015362

NKP1
Inner kinetochore subunit NKP1

1

0

High-throughput

0.480

High

381502

GAL1
Galactokinase

1

0

High-throughput

0.479

High

994437

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

0

High-throughput

0.479

High

549637

KCY
Uridylate kinase

1

3

High-throughput

0.479

High

663662

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

858509

SAP4
SIT4-associating protein SAP4

1

3

High-throughput

0.479

High

959900

NUM1
Nuclear migration protein NUM1

1

20

High-throughput

0.479

High

978376

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

755760

ORC6
Origin recognition complex subunit 6

1

0

High-throughput

0.460

High

775900

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

812663

BCA2
Branched-chain-amino-acid aminotransferase, cytosolic

1

0

High-throughput

0.458

High

357580

RLA4
Large ribosomal subunit protein P2B

1

2

High-throughput

0.457

High

447009

EI2BG
Translation initiation factor eIF2B subunit gamma

1

2

High-throughput

0.457

High

715909

ATG19
Autophagy-related protein 19

1

1

High-throughput

0.457

High

772394

VPS27
Vacuolar protein sorting-associated protein 27

1

7

Small-scale

0.457

High

797242

BUD27
Bud site selection protein 27

1

2

High-throughput

0.457

High

817424

PFD3
Prefoldin subunit 3

1

1

High-throughput

0.457

High

860183

YG1D
Probable transcriptional regulatory protein HAH1

1

1

High-throughput

0.457

High

972964

YP077
Uncharacterized protein YPL077C

1

2

High-throughput

0.457

High

978999

ARA2
D-arabinose 1-dehydrogenase

1

2

High-throughput

0.457

High

994473

BRX1
Ribosome biogenesis protein BRX1

1

3

High-throughput

0.457

High

1015271

BUG1
Binder of USO1 and GRH1 protein 1

1

1

High-throughput

0.457

High

521079

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.457

High

478612

HSP77
Import motor subunit, mitochondrial

1

20

High-throughput

0.445

High

773792

6P21
6-phosphofructo-2-kinase 1

1

11

High-throughput

0.445

High

336273

CCPR
Cytochrome c peroxidase, mitochondrial

1

1

High-throughput

0.437

High

692970

SPT16
FACT complex subunit SPT16

1

4

Small-scale

0.437

High

744347

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

1

High-throughput

0.437

High

860231

TIM21
Mitochondrial import inner membrane translocase subunit TIM21

1

0

High-throughput

0.279

Low

732868

DID4
DOA4-independent degradation protein 4

1

0

High-throughput

0.261

Low

977357

SRC1
Inner nuclear membrane protein SRC1

1

0

High-throughput

0.261

Low

989238

MDM36
Mitochondrial distribution and morphology protein 36

1

0

High-throughput

0.261

Low

991354

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024