Protein: EFTU1
Elongation factor Tu 1 (EF-Tu 1) (Bacteriophage Q beta RNA-directed RNA polymerase subunit III) (P-43)

Gene: EFTU1, tufA
Organism: Escherichia coli K-12
Interactions: 173
UniProt ID: P0CE47

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003746 - translation elongation factor activity
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

458600

EFTS
Elongation factor Ts

4

8

Small-scale

0.901

High

415814

ERA
GTPase Era

2

7

High-throughput

0.789

High

474140

EFTU2
Elongation factor Tu 2

2

7

High-throughput

0.767

High

464953

LON
Lon protease

2

2

High-throughput

0.759

High

458560

EFG
Elongation factor G

1

10

High-throughput

0.625

High

340922

DPO1
DNA polymerase I

2

2

High-throughput

0.611

High

343740

SYI
Isoleucine--tRNA ligase

2

11

High-throughput

0.611

High

368578

DNAA
Chromosomal replication initiator protein DnaA

2

1

High-throughput

0.611

High

368613

DPO3E
DNA polymerase III subunit epsilon

2

2

High-throughput

0.611

High

409412

TSAD
tRNA N6-adenosine threonylcarbamoyltransferase

2

1

High-throughput

0.611

High

458395

HSLU
ATP-dependent protease ATPase subunit HslU

2

5

High-throughput

0.611

High

463519

YBED
UPF0250 protein YbeD

2

1

High-throughput

0.611

High

466997

DNAB
Replicative DNA helicase

2

3

High-throughput

0.611

High

469170

RHO
Transcription termination factor Rho

2

4

High-throughput

0.611

High

474144

LPXB
Lipid-A-disaccharide synthase

2

1

High-throughput

0.611

High

474145

DPO3A
DNA polymerase III subunit alpha

2

1

High-throughput

0.611

High

474149

HELD
DNA helicase IV

2

5

High-throughput

0.611

High

474154

SRMB
ATP-dependent RNA helicase SrmB

2

6

High-throughput

0.611

High

474155

RNE
Ribonuclease E

2

1

High-throughput

0.611

High

474157

MUKB
Chromosome partition protein MukB

2

3

High-throughput

0.611

High

474163

MUTS
DNA mismatch repair protein MutS

2

4

High-throughput

0.611

High

474178

RLMN
Dual-specificity RNA methyltransferase RlmN

2

2

High-throughput

0.611

High

474184

HRPA
ATP-dependent RNA helicase HrpA

2

1

High-throughput

0.611

High

474188

CAN
Carbonic anhydrase 2

2

1

High-throughput

0.611

High

474205

DXS
1-deoxy-D-xylulose-5-phosphate synthase

2

3

High-throughput

0.611

High

459686

KPRS
Ribose-phosphate pyrophosphokinase

2

3

High-throughput

0.594

High

458530

HSCB
Co-chaperone protein HscB

2

1

High-throughput

0.588

High

458938

HFQ
RNA-binding protein Hfq

2

1

High-throughput

0.588

High

463171

UBIE
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE

2

3

High-throughput

0.588

High

463960

RPOB
DNA-directed RNA polymerase subunit beta

2

5

High-throughput

0.588

High

465322

ULAR
HTH-type transcriptional regulator UlaR

2

1

High-throughput

0.588

High

466389

FTSA
Cell division protein FtsA

2

8

High-throughput

0.588

High

468182

UVRY
Response regulator UvrY

2

3

High-throughput

0.588

High

468472

GYRA
DNA gyrase subunit A

2

1

High-throughput

0.588

High

469560

SRP54
Signal recognition particle protein

2

2

High-throughput

0.588

High

469916

RLME
Ribosomal RNA large subunit methyltransferase E

2

1

High-throughput

0.588

High

473818

GATY
D-tagatose-1,6-bisphosphate aldolase subunit GatY

2

1

High-throughput

0.588

High

474190

CLPB
Chaperone protein ClpB

2

7

High-throughput

0.588

High

474147

TDCD
Propionate kinase

2

0

High-throughput

0.585

High

343444

XYLA
Xylose isomerase

2

1

High-throughput

0.571

High

421429

SYV
Valine--tRNA ligase

2

11

High-throughput

0.571

High

442705

DNAJ
Chaperone protein DnaJ

2

7

High-throughput

0.571

High

463473

YAAA
DNA-binding and peroxide stress resistance protein YaaA

2

1

High-throughput

0.571

High

464060

YIDA
Sugar phosphatase YidA

2

1

High-throughput

0.571

High

466432

CLPA
ATP-dependent Clp protease ATP-binding subunit ClpA

2

9

High-throughput

0.571

High

474164

ACRF
Multidrug export protein AcrF

2

1

High-throughput

0.571

High

474179

FBPC
Fe(3+) ions import ATP-binding protein FbpC

2

8

High-throughput

0.571

High

474194

CUTA
Divalent-cation tolerance protein CutA

2

1

High-throughput

0.571

High

474209

YAJL
Protein/nucleic acid deglycase 3

2

2

Small-scale

0.571

High

474143

SECA
Protein translocase subunit SecA

1

1

High-throughput

0.561

High

474148

RPOS
RNA polymerase sigma factor RpoS

1

1

High-throughput

0.561

High

474152

MURC
UDP-N-acetylmuramate--L-alanine ligase

1

1

High-throughput

0.561

High

421104

MALT
HTH-type transcriptional regulator MalT

2

1

High-throughput

0.558

High

474165

FDNG
Formate dehydrogenase, nitrate-inducible, major subunit

2

3

High-throughput

0.558

High

474166

HYPD
Hydrogenase maturation factor HypD

2

1

High-throughput

0.558

High

474185

UBIU
Ubiquinone biosynthesis protein UbiU

2

2

High-throughput

0.558

High

474197

YBJX
Uncharacterized protein YbjX

2

1

High-throughput

0.558

High

474208

UACR
Putative uric acid sigma-54-dependent transcriptional regulator UacR

2

1

High-throughput

0.558

High

336825

RIR1
Ribonucleoside-diphosphate reductase 1 subunit alpha

1

2

High-throughput

0.536

High

340877

RPOD
RNA polymerase sigma factor RpoD

1

1

High-throughput

0.536

High

343758

SYA
Alanine--tRNA ligase

1

3

High-throughput

0.536

High

392825

KDSB
3-deoxy-manno-octulosonate cytidylyltransferase

1

1

High-throughput

0.536

High

439433

USG
USG-1 protein

1

1

High-throughput

0.536

High

449045

GRPE
Protein GrpE

1

2

High-throughput

0.536

High

459031

HSLO
33 kDa chaperonin

1

1

High-throughput

0.536

High

460183

HSLV
ATP-dependent protease subunit HslV

1

1

High-throughput

0.536

High

462342

RS5
Small ribosomal subunit protein uS5

1

3

High-throughput

0.536

High

474141

RNPH
Truncated inactive ribonuclease PH

1

8

High-throughput

0.536

High

474162

YICC
Endoribonuclease YicC

1

1

High-throughput

0.536

High

474168

PEPT
Peptidase T

1

1

High-throughput

0.536

High

474169

MOAA
GTP 3',8-cyclase

1

1

High-throughput

0.536

High

474171

GLMM
Phosphoglucosamine mutase

1

1

High-throughput

0.536

High

474174

NIKD
Nickel import ATP-binding protein NikD

1

14

High-throughput

0.536

High

474177

CBPA
Curved DNA-binding protein

1

4

High-throughput

0.536

High

474183

YJJV
Uncharacterized metal-dependent hydrolase YjjV

1

2

High-throughput

0.536

High

474189

RISB
6,7-dimethyl-8-ribityllumazine synthase

1

1

High-throughput

0.536

High

474200

DMLA
D-malate dehydrogenase [decarboxylating]

1

4

High-throughput

0.536

High

474203

DGCM
Diguanylate cyclase DgcM

1

2

High-throughput

0.536

High

474206

YDHQ
Protein YdhQ

2

1

High-throughput

0.521

High

474153

PNCB
Nicotinate phosphoribosyltransferase

1

0

High-throughput

0.513

High

474180

PTKB
PTS system galactitol-specific EIIB component

1

0

High-throughput

0.513

High

474182

RSGA
Small ribosomal subunit biogenesis GTPase RsgA

1

0

High-throughput

0.513

High

448067

NARG
Respiratory nitrate reductase 1 alpha chain

1

3

High-throughput

0.489

High

474146

NARH
Respiratory nitrate reductase 1 beta chain

1

2

High-throughput

0.489

High

474156

RECJ
Single-stranded-DNA-specific exonuclease RecJ

1

1

High-throughput

0.489

High

474158

MURI
Glutamate racemase

1

1

High-throughput

0.489

High

474192

YHES
Probable ATP-binding protein YheS

1

6

High-throughput

0.489

High

474199

RLHA
23S rRNA 5-hydroxycytidine C2501 synthase

1

2

High-throughput

0.489

High

474201

YOAA
Probable ATP-dependent DNA helicase YoaA

1

1

High-throughput

0.489

High

458310

CLPP
ATP-dependent Clp protease proteolytic subunit

1

2

High-throughput

0.484

High

458696

FABA
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase

1

1

High-throughput

0.484

High

458724

FABZ
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ

1

1

High-throughput

0.484

High

459161

DNAK
Chaperone protein DnaK

1

7

High-throughput

0.484

High

459598

KDSA
2-dehydro-3-deoxyphosphooctonate aldolase

1

1

High-throughput

0.484

High

459768

KTHY
Thymidylate kinase

1

2

High-throughput

0.484

High

459861

MURA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase

1

2

High-throughput

0.484

High

460087

PLSB
Glycerol-3-phosphate acyltransferase

1

1

High-throughput

0.484

High

460121

IPYR
Inorganic pyrophosphatase

1

4

High-throughput

0.484

High

460217

PTH
Peptidyl-tRNA hydrolase

1

1

High-throughput

0.484

High

462771

RUVB
Holliday junction branch migration complex subunit RuvB

1

6

High-throughput

0.484

High

462788

METK
S-adenosylmethionine synthase

1

1

High-throughput

0.484

High

463242

PSRP
Phosphoenolpyruvate synthase regulatory protein

1

1

High-throughput

0.484

High

463708

SYK2
Lysine--tRNA ligase, heat inducible

1

9

High-throughput

0.484

High

464480

FTSZ
Cell division protein FtsZ

1

4

High-throughput

0.484

High

465002

PTA
Phosphate acetyltransferase

1

1

High-throughput

0.484

High

465252

FTSE
Cell division ATP-binding protein FtsE

1

8

High-throughput

0.484

High

465388

MREB
Cell shape-determining protein MreB

1

12

High-throughput

0.484

High

465838

PSTB
Phosphate import ATP-binding protein PstB

1

7

High-throughput

0.484

High

467073

MBHM
Hydrogenase-2 large chain

1

2

High-throughput

0.484

High

467086

HINT
Purine nucleoside phosphoramidase

1

2

High-throughput

0.484

High

468302

MIAB
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase

1

1

High-throughput

0.484

High

468496

GYRB
DNA gyrase subunit B

1

1

High-throughput

0.484

High

468753

NUSA
Transcription termination/antitermination protein NusA

1

1

High-throughput

0.484

High

469751

IBPA
Small heat shock protein IbpA

1

2

High-throughput

0.484

High

469777

IBPB
Small heat shock protein IbpB

1

2

High-throughput

0.484

High

474191

MLAF
Intermembrane phospholipid transport system ATP-binding protein MlaF

1

12

High-throughput

0.484

High

474196

RIR2
Ribonucleoside-diphosphate reductase 1 subunit beta

1

1

High-throughput

0.484

High

421151

POXB
Pyruvate dehydrogenase [ubiquinone]

1

2

High-throughput

0.479

High

452038

PUTA
Bifunctional protein PutA [Includes: Proline dehydrogenase

1

5

High-throughput

0.479

High

454983

GLTD
Glutamate synthase [NADPH] small chain

1

1

High-throughput

0.479

High

457687

CH60
Chaperonin GroEL

1

1

Small-scale

0.479

High

459913

NAGB
Glucosamine-6-phosphate deaminase

1

2

High-throughput

0.479

High

464262

ALAA
Glutamate-pyruvate aminotransferase AlaA

1

1

High-throughput

0.479

High

465907

FDNH
Formate dehydrogenase, nitrate-inducible, iron-sulfur subunit

1

2

High-throughput

0.479

High

468993

YCFH
Uncharacterized metal-dependent hydrolase YcfH

1

2

High-throughput

0.479

High

474151

PRIA
Primosomal protein N'

1

4

High-throughput

0.479

High

474159

ISPA
Farnesyl diphosphate synthase

1

1

High-throughput

0.479

High

474198

LOLD
Lipoprotein-releasing system ATP-binding protein LolD

1

8

High-throughput

0.479

High

460295

PYRH
Uridylate kinase

1

0

High-throughput

0.464

High

463190

RAPZ
RNase adapter protein RapZ

1

0

High-throughput

0.464

High

464677

LDCI
Inducible lysine decarboxylase

1

0

High-throughput

0.464

High

466605

HOLE
DNA polymerase III subunit theta

1

0

High-throughput

0.464

High

467804

VIAA
Protein ViaA

1

0

High-throughput

0.464

High

469083

SSPB
Stringent starvation protein B

1

0

High-throughput

0.464

High

469147

SPOT
Bifunctional

1

0

High-throughput

0.464

High

367396

PBPA
Penicillin-binding protein 1A

1

0

High-throughput

0.458

High

459458

HYPA
Hydrogenase maturation factor HypA

1

0

High-throughput

0.458

High

464216

RIMI
[Ribosomal protein bS18]-alanine N-acetyltransferase

1

0

High-throughput

0.458

High

467505

LAPA
Lipopolysaccharide assembly protein A

1

0

High-throughput

0.458

High

469039

RMF
Ribosome modulation factor

1

0

High-throughput

0.458

High

469688

YHBY
RNA-binding protein YhbY

1

0

High-throughput

0.458

High

474150

MURG
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

1

0

High-throughput

0.458

High

474161

PHOP
Transcriptional regulatory protein PhoP

1

0

High-throughput

0.458

High

343889

SYGA
Glycine--tRNA ligase alpha subunit

1

1

High-throughput

0.445

High

439452

RECB
RecBCD enzyme subunit RecB

1

3

High-throughput

0.445

High

458357

CLPX
ATP-dependent Clp protease ATP-binding subunit ClpX

1

7

High-throughput

0.445

High

458868

GREA
Transcription elongation factor GreA

1

1

High-throughput

0.445

High

461807

RS2
Small ribosomal subunit protein uS2

1

5

High-throughput

0.445

High

463533

RHLB
ATP-dependent RNA helicase RhlB

1

5

High-throughput

0.445

High

469568

SSB
Single-stranded DNA-binding protein

1

2

High-throughput

0.445

High

474142

RCSB
Transcriptional regulatory protein RcsB

1

3

High-throughput

0.445

High

474172

RAVA
ATPase RavA

1

9

High-throughput

0.445

High

474176

YEJF
Uncharacterized ABC transporter ATP-binding protein YejF

1

14

High-throughput

0.445

High

474181

USPG
Universal stress protein UP12

1

1

High-throughput

0.445

High

474187

RL4
Large ribosomal subunit protein uL4

1

3

High-throughput

0.445

High

467411

CRA
Catabolite repressor/activator

1

2

High-throughput

0.442

High

474160

MUTL
DNA mismatch repair protein MutL

1

2

High-throughput

0.437

High

474170

METN
Methionine import ATP-binding protein MetN

1

10

High-throughput

0.437

High

420996

CCA
Multifunctional CCA protein [Includes: CCA-adding enzyme

1

1

High-throughput

0.407

High

474175

NIKE
Nickel import ATP-binding protein NikE

1

12

High-throughput

0.407

High

467902

RSMD
Ribosomal RNA small subunit methyltransferase D

2

0

High-throughput

0.318

High

474207

QUEC
7-cyano-7-deazaguanine synthase

2

0

High-throughput

0.318

High

459441

NIKR
Nickel-responsive regulator

1

0

High-throughput

0.279

Low

474173

NIKA
Nickel-binding periplasmic protein

1

0

High-throughput

0.279

Low

474186

ABPB
Anti-bacteriophage protein B

1

0

High-throughput

0.279

Low

474202

LYSAC
Peptidyl-lysine N-acetyltransferase PatZ

1

0

High-throughput

0.279

Low

474204

YQAB
Fructose-1-phosphate phosphatase YqaB

1

0

High-throughput

0.279

Low

474167

METQ
D-methionine-binding lipoprotein MetQ

1

0

High-throughput

0.261

Low

463819

ARGP
HTH-type transcriptional regulator ArgP

1

0

High-throughput

0.253

Low

466215

END3
Endonuclease III

1

0

High-throughput

0.253

Low

468105

CEDA
Cell division activator CedA

1

0

High-throughput

0.253

Low

474193

YDIH
Uncharacterized protein YdiH

1

0

High-throughput

0.253

Low

474195

MBHS
Hydrogenase-1 small chain

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024